Excited to have been able to collaborate with @labfriedman.bsky.social on this exciting new study that uncovers a new layer of regulation for BNIP3 and NIX!

Jonathan Friedman@labfriedman.bsky.social · last mo.

New preprint from our lab! We uncover how a subset of mitophagy proteins BNIP3 and NIX are repressed and protected from turnover, we think so that they can perform a surveillance role to detect mitochondrial dysfunction under basal conditions. t.co/4XKkd4LsFi

New preprint from our lab! We uncover how a subset of mitophagy proteins BNIP3 and NIX are repressed and protected from turnover, we think so that they can perform a surveillance role to detect mitochondrial dysfunction under basal conditions. t.co/4XKkd4LsFi

Check out our highlight of the most recent example of subcellular mitochondrial specialization in @currentbiology.bsky.social. Be sure to also check out the beautiful work from David Sherwood's lab www.cell.com/current-biol...

Mitochondrial biology: Specialized powerhouses pack a punch

A new study reveals that a specialized population of mitochondria in the Caenorhabditis elegans uterine anchor cell is remodeled and enriched in machinery needed for optimal local energy production to...

cell.com

A reminder to join us at 12pm ET today!

Jonathan Friedman@labfriedman.bsky.social · 4mo ago

I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join for talks from @zakbaker.bsky.social (from @pagliarini-lab.bsky.social) and Sara Wong (from Adam Hughes' lab) on the intersection of mitochondria and lipid metabolism! Register here: www.asbmb.org/meetings-eve...

I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join for talks from @zakbaker.bsky.social (from @pagliarini-lab.bsky.social) and Sara Wong (from Adam Hughes' lab) on the intersection of mitochondria and lipid metabolism! Register here: www.asbmb.org/meetings-eve...

Lipid Research Division Seminar Series

April 9, 2026 | 12 p.m. Eastern

asbmb.org

Excited to share that we are hiring a research assistant for my lab at UTSW in Dallas (www.nils-burger-lab.com). Please share with your mentees. utsw.taleo.net/careersectio... We are also looking for motivated, curious, and enthusiastic postdoctoral fellows!

Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!

Does anyone have a favorite mNeonGreen antibody that works well for western and IPs?

Finally, we find that presequence strength influences yeast metabolism in a model of COX4 deletion. When fused to a leaderless COX4, only presequences that promote “strong” import behavior restore respiratory growth to wild-type levels. 8/n

Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵 www.biorxiv.org/content/10.1...

Mitochondrial presequences harbor variable strengths to maintain organellar function

Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...

biorxiv.org

Niemi lab and @washubbsb.bsky.social graduate student Youmian Yan gave a fantastic presentation on her work at the @asbmb.bsky.social meeting in Chicago! #ProudPI (photo credit to @kerikozul.bsky.social)

This is a very sad day. Shock, despair, disappointment, disbelief... These only scratch the surface in describing this decision and how I feel. I began my career in Parkinson's research in Richard's lab. What happens now to all the trainees still there?

WIRED@wired.com · last yr.

NEW: The doctor behind breakthrough Parkinson’s research was among the scientists purged from the National Institutes of Health, the US’s leading medical research agency. www.wired.com/story/doctor...

Come to St. Louis this summer for the United Mitochondrial Disease Foundation MitoMed 2025 Conference! We have a fantastic line up with lots of opportunities for short talks. We're also running a Masterclass for Early Career Investigators. More info here: www.umdfconference.org

Reminder to join us tomorrow at 12pm ET!

Jonathan Friedman@labfriedman.bsky.social · last yr.

Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series. We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab. Register here! www.asbmb.org/meetings-eve...

Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series. We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab. Register here! www.asbmb.org/meetings-eve...

Lipid Research Division Seminar Series

March 26, 2025 | 12 p.m. Eastern

asbmb.org

Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now @currentbiology.bsky.social! Led by fantastic @madeleinempavey.bsky.social! www.cell.com/current-biol...

Compositionally unique mitochondria in filopodia support cellular migration

Marlar-Pavey et al. determine that a subpopulation of compositionally unique mitochondria, METEORs, dynamically localize to filopodia. Loss of mitochondrial targeting to filopodia correlates with a re...

cell.com

An excellent opportunity!

Jeremy Baskin@jeremybaskin.bsky.social · last yr.

Some good news: applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology at Cornell should apply by Apr 14. Please repost! wicmb.cornell.edu/emerging-sch...

It’s so nice to be able to celebrate something this week. Newest work from the group! How are nuclear contents delivered to the cytosolic autophagy machinery while maintaining nuclear integrity? Nuclear envelope gymnastics! Cool role for Dnm1/Drp1. www.nature.com/articles/s41...

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope - Nature Cell Biology

Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for d...

nature.com

In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:

A big congrats to Alia on a successful thesis defense! @themitotracker.bsky.social gave an excellent talk and did the lab proud! 🥳🎉🍾

New: @themitotracker.bsky.social et al. from @labfriedman.bsky.social identify a mitochondrial inner membrane protein that marks and facilitates a subset of sites of mitochondrial fission in human cells. rupress.org/jcb/article/...

Looking for some holiday reading material? Our latest paper identifying a new player in mitochondrial fission is now out @jcellbiol.bsky.social! A wonderful early present to see this now online! rupress.org/jcb/article/...

I’m ultra excited about our preprints on mitochondrial pearling. In two concurrent collaborative studies with @wallaceucsf.bsky.social, we investigated its consequences on mtDNA nucleoids (led by @jclandoni.bsky.social) & its biophysical causes (led by @gavsturm.bsky.social). Funders HFSP, ERC, SNSF

Our executive editor with Alia Edington @themitotracker.bsky.social from @labfriedman.bsky.social, winner of the 2024 Alan Hall Travel Award! 👉 Be sure to catch Alia's talk today at #CellBio2024! Read about his year's winners: https://buff.ly/4gtpqRk

Excited to announce that I was awarded the Alan Hall Travel Award from @jcellbiol.bsky.social to attend #CellBio2024 this weekend! If you're attending this year, please join me at my poster or my talk (details below) to learn about my story on novel mediators of mitochondrial dynamics!

Journal of Cell Biology@jcb.org · 2y ago

🎉 Congratulations to Alia Edington @themitotracker.bsky.social the winner of 2024 Alan Hall Travel Award! Alia is a graduating PhD student from @labfriedman.bsky.social. 👉 Be sure to catch Alia's talk during #CellBio2024! Read about his year's winners: https://buff.ly/4ffCQz8

Congrats Alia! 🎉🎉 Well deserved!

Journal of Cell Biology@jcb.org · 2y ago

🎉 Congratulations to Alia Edington @themitotracker.bsky.social the winner of 2024 Alan Hall Travel Award! Alia is a graduating PhD student from @labfriedman.bsky.social. 👉 Be sure to catch Alia's talk during #CellBio2024! Read about his year's winners: https://buff.ly/4ffCQz8

So proud of Alia Edington @themitotracker.bsky.social for winning the JCB Alan Hall Travel award to attend ASCB! Thank you @jcellbiol.bsky.social for recognizing the hard work of our trainees! Be sure to check out Alia's talk 5pm Mon. in the organelle subgroup or at poster B143 Sun. 11:15!

Tim@timisstuck.bsky.social · 2y ago

A huge congratulations to the winner of JCB's Alan Hall award, Alia Edington from the Friedman lab at UTSW And to the winner of our Norton B Gilula award, Justin Krish Williams from the Schekman lab at UC Berkeley! rupress.org/jcb/pages/al...

As you're planning out your ASCB schedule be sure to attend the organelle-focused special interest group hosted by @nieminm.bsky.social and myself Mon. 12/16 at 5pm Come hear a fantastic lineup of speakers including @walterwchen.bsky.social @themitotracker.bsky.social @lianjiejerrywei.bsky.social

Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!

Ewa Bomba-Warczak@ebomba.bsky.social · 2y ago

MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!