Two more interesting science talks approaching in a few days (November 3rd), via the @genomeiinetwork.bsky.social. Join us clicking here! 👇 uzh.zoom.us/j/6598481621...
Sarah Lambert's Lab
@lambertsarahlab.bsky.social
Our team investigates the mechanisms ensuring genome maintenance in response to DNA insults and DNA replication failures.
Our Dept. of Genetics and Developmental Biology at the Institut Curie in the heart of Paris is hiring a new junior PI. It has a nice start up package and excellent I. Curie facilities. Please spread the word: Deadline Dec. 18th! jpi-recruitment-curie-umr3215-u934.curie.fr
Call for applications - Junior Group Leader (M/F)
jpi-recruitment-curie-umr3215-u934.curie.fr
Interested in #CellCycle regulation and #DevelopmentalBiology? Sign up for the EMBO Workshop "Cycling towards fate: Cell cycle control in development" in Amsterdam, NL, 7–10 June 2027. Deadline: 1 February 2027 https://meetings.embo.org/event/27-cell-cycle-control #EMBOcellCycle #EMBOevents 🧪
Cycling towards fate: cell-cycle control in development
The tight control of cell division is fundamental to multicellular development, ensuring the formation of tissues and organs with the correct size, shape and function. This EMBO Workshop brings toget…
meetings.embo.org
🏅 Congratulations to Fadma Lakhal, PhD student at Institut Curie, recipient of the 2026 L’Oréal-UNESCO For Women in Science France Award for her research on Rad51, a key protein in DNA repair. 🔎 Read more : institut-curie.org/news/fadma-l...
Can RNA itself drive toxicity in Huntington’s disease? Join the Kaiser lab (Bijvoet Centre, Utrecht University) to tackle this question using cutting-edge single-molecule biophysics, optical tweezers & fluorescence microscopy. www.uu.nl/en/organisat...
PhD Position on Biophysical Origins of RNA Toxicity in Huntington’s Disease
Exciting Opportunity for a PhD Researcher: Join our team to investigate molecular mechanisms in Huntington’s Disease!
uu.nl
📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr
Are you interested in learning how genomes of weird fungi and protists evolve and are you looking for an exciting PhD opportunity? Jolien van Hooff and I are looking for an enthusiasic PhD candidate at Wageningen University: www.wur.nl/en/vacancy/p... #TEworldwide #Fungi #Protists #Genome
PhD position in genome evolution and architecture in unicellular eukaryotes
Are you fascinated by how eukaryotic genomes evolve? Do you want to look beyond model organisms and point mutations to uncover the complexity of genome evolution?
wur.nl
Last chance to register for the EMBO Workshop on Evolution and Diversity of the DNA Damage Response! Due to technical issues with the website over the past few days, we have extended the deadline to Friday, 9 October. meetings.embo.org/event/27-dna...
Evolution and diversity of the DNA damage response
To cope with the threat of genome instability, cells have evolved an intricate network of mechanisms ranging from cell cycle checkpoints to specialized DNA repair pathways known as the DNA damage res…
meetings.embo.org
Today, the #NobelPrize in Physiology or Medicine was announced. Interested in how the #research developed? 🧪 In 2017, @emboreports.org @embopress.org interviewed Karl Deisseroth, one of the Nobel Prize winners, about his work on #optogenetics and more: link.springer.com/article/10.1...
Great science talks are coming up again, via the @genomeiinetwork.bsky.social, in two days from now (Tue Oct 6th). Don't miss them! 👇
Huge congrats to @susankilgas.bsky.social on receiving a 2026 King Trust Postdoctoral Fellowship! 🎉 We are so happy to see your hard work recognized and excited for the research this fellowship will support over the next two years! Congratulations to all of this year’s fellows! lnkd.in/p/eCbW9_gm
#biomedicalresearch #researchfunding #healthresearch #kingtrust #scientificresearch | Health Resources in Action (HRiA)
Scientific breakthroughs begin with investments in promising researchers. Congratulations to the 2026 cohort of King Trust Postdoctoral Fellowship Program Awardees, who will receive two years of fund...
lnkd.in
Our next seminar is on Tuesday, October 6 from 5-6PM (Rome), 11-12AM (NYC). We are excited to host two fantastic speakers Jo Morris and @garinis.bsky.social, who will share their latest research with us. Don't miss it! Zoom link: uzh.zoom.us/j/6598481621...
Just published: PUM3 is an essential suppressor of replication stress in homologous recombination deficient breast cancer; large collaborative effort lead by Breast Cancer Now (Pettit, Lord and Tutt) inc. supporting data from the GDSC (Pearl, Oliver). doi.org/10.1038/s414...
PUM3 is an essential suppressor of replication stress in homologous recombination deficient breast cancer - Nature Communications
How tumour cells survive defective homologous recombination (HR) DNA repair has not been fully understood. Here the authors find that PUM3 prevents transcription replication conflicts and…
doi.org
Registration deadline extended to 5 October for the EMBO Workshop "#Evolution and diversity of the DNA damage response" in Bengaluru, India, 23–27 February 2027. https://meetings.embo.org/event/27-dna-damage-response #EMBOdnadamage #LifeSciences #EMBOevents 🧪
Evolution and diversity of the DNA damage response
To cope with the threat of genome instability, cells have evolved an intricate network of mechanisms ranging from cell cycle checkpoints to specialized DNA repair pathways known as the DNA damage res…
meetings.embo.org
Working with a great team to organize @keystoneSymposia.bsky.social DNA Replication: Pathway Crosstalk Shaping Physiology and Disease, this April! Join us to explore emerging research in London! keysym.us/KSDNA27 #KSDNA27
DNA Replication: Pathway Crosstalk Shaping Physiology and Disease | Keystone Symposia
Join us at the Keystone Symposia on DNA Replication: Pathway Crosstalk Shaping Physiology and Disease, April 2027, in London, with field leaders!
keysym.us
Take a look at the EMBO Workshop on Evolution and Diversity of the DDR (Feb 23–27, 2027, India). There are plenty of speaking slots for trainees selected from submitted abstracts. Great opportunity to share your work and join the discussion! meetings.embo.org/event/27-dna...
Evolution and diversity of the DNA damage response
To cope with the threat of genome instability, cells have evolved an intricate network of mechanisms ranging from cell cycle checkpoints to specialized DNA repair pathways known as the DNA damage res…
meetings.embo.org
There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss
EMBO is #hiring a Programme Assistant for the EMBO Young Investigator Programme (absence cover) – Apply now! https://www.embo.org/vacancy/programme-assistant-embo-young-investigator-programme-absence-cover/ #JobOpening #JobSearch #CareerOpportunities 🧪
Thrilled to share a new important study from the lab, published today in @nature.com, showing how cohesin mediates efficient replication fork plasticity and stress response, using its loop extrusion activity to promote 3D contacts on replicating DNA: www.nature.com/articles/s41...
Cohesin reshapes replication fork contacts to aid fork slowing and reversal - Nature
Cohesin-mediated loop extrusion limits sister-fork coupling and tethers nearby replication forks under replication stress, promoting fork reversal and slowing fork progression to safeguard genome...
nature.com
We are recruiting a postdoctoral fellow to study DNA damage repair via the homologous recombination pathway using quantitative cell biology approaches. The position will be initially supported for two years by the MSU Research Foundation Postdoctoral Scholars program. Please share! 1/5
How are mitotic chromosomes built? Our Review @cp-trendsgenetics.bsky.social revisits the classical chromosome scaffold model and connects it to condensins, topoIIα, and physical forces. We propose interphase chromatin domains as “building blocks”🧩of chromosomes: authors.elsevier.com/a/1nmwrcQbJI...
📣 Looking forward to hearing all about topoisomerases and precision oncology from Prof. Yves Pommier from National Cancer Institute (NCI-NIH) tomorrow at 12pm at CBM @cbm-csic-uam.bsky.social, come join us!
Delve into different aspects of the #DNAdamageResponse at the EMBO Workshop "#Evolution and diversity of the DNA damage response" in Bengaluru, India, 23–27 February 2027. Deadline: 15 September 2026 https://meetings.embo.org/event/27-dna-damage-response #EMBOdnadamage #LifeSciences #EMBOevents 🧪
1/ out in @science.org! We found a new asymmetry in large-scale chromosome structure: sister chromatids are shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! A close collaboration w/ @gerlichlab.bsky.social , led by @flaviacorsi.bsky.social www.science.org/doi/10.1126/...
Let's begin the 2026 Fall Season of GIIN Seminars! 🍂 Join us live on Tuesday, September 1st at 5pm (Rome) / 11am (NYC) for an exciting webinar featuring @chiololab.bsky.social o and Jean-Yves Masson! Zoom link: uzh.zoom.us/j/6598481621...
Our latest work describing DDIAS as a new component of the TOPBP1-CIP2A pathway in mitosis and its requirement for brain development is now published. Fantastic collaboration with @fenaochs.bsky.social, @profstewartlab.bsky.social, Lars Allan Larsen, @tcr-miller.bsky.social, Zafar Iqbal & others
Cell - a Cell Press journal@cp-cell.bsky.social · 2mo agoNow online! DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development
Happy to share a brand new story from the group! Started in 2019, stopped for pandemic and revived in 2025. Kudos to all authors and especially to Benedetta and Floriana who is taking the challenge! Take-home message: even small deviations from the norm can make big changes in life... Stay tuned!
bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 2mo agoSubthreshold perturbation of DNA replication induces a secretory response and a bystander effect in naïve human fibroblasts https://www.biorxiv.org/content/10.64898/2026.08.20.745990v1
Treat biological databases as infrastructure, not projects www.nature.com/articles/d41... We're quietly defunding the infrastructure modern biology runs on. PomBase, FlyBase, HGNC. have faced, or facing, existential funding crises since 2024. Curation expertise, once lost, is difficult to rebuild.
Treat biological databases as infrastructure, not projects
Letter to the Editor
nature.com
I am happy to share our latest paper on human PIF1, a wonderful collaboration with Raphael Guerois, Ralf Seidel and Ulrich Rass and their teams. Human PIF1 is quite different from its yeast counterpart. Congratulations to Akshay Jayachandran, the first author. genesdev.cshlp.org/content/earl...
Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org