Eating the Dead: E-cadherin keeps epithelial cells together and equips them for devouring cellular debris 📷 Hanna-Maria Häkkinen, Marta Batet & @laurafbianchi.bsky.social et al @crg.eu in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026... with @rooph.bsky.social

Ever wondered how epithelial cells clear apoptotic cells while maintaining tissue cohesion?🍝🔗 Check our new paper in which we show that E-cadherin plays a dual role in regulating basal cortex dynamics upon phagocytosis while maintaining connected tissue organization www.nature.com/articles/s41...

De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance - Nature Communications

Epithelial cells remodel their shape during phagocytosis while preserving tissue cohesion. Here, authors show that the E-cadherin/catenin adhesion complex is repurposed at phagocytic contacts, where i...

nature.com

How does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work! www.nature.com/articles/s41... www.nature.com/articles/s41...

Target cell cortical tension regulates macrophage trogocytosis - Nature Cell Biology

Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...

nature.com

I'm extremely happy to say that a new preprint from Ruprecht lab is out! Check it to to know more about a novel role for the E-cadherin/catenin complex in controlling epithelial phagocytosis 🍽🐟🔬

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 11mo ago

De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance https://www.biorxiv.org/content/10.64898/2025.12.08.692667v1

Features new works from Stankunas Lab @uoregon.bsky.social, Ruprecht Lab @crg.eu & @campaslab.bsky.social (albeit mammals this time 😉)

FocalPlane @focalplane.bsky.social · 11mo ago

ICYMI, our #preprint list is now up on FocalPlane, highlighting the latest research using #microscopy to answer questions in #biology. As always, send us any recommendations for preprints that we've missed: focalplane.biologists.com/2025/12/12/m...

De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance https://www.biorxiv.org/content/10.64898/2025.12.08.692667v1

How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by @pauguillamat.bsky.social‬ www.biorxiv.org/content/10.1...

Thrilled to share that our "Poster at a Glance" on #Phagocytosis is out! Thank you @jcellsci.bsky.social @biologists.bsky.social for the invitation ! Prepared with @manondepierre.bsky.social @chiarapompili.bsky.social from @institutcochin.bsky.social journals.biologists.com/jcs/article/...

Phagocytosis at a glance

Summary: Phagocytosis involves receptor-driven actin and membrane remodelling to engulf microbes and debris. The phagosome then matures for degradation, supporting both nutrition and immune responses.

journals.biologists.com

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story: www.cell.com/cell-host-mi...

I knew there would be an effect! This has been one of the questions that I had for the longest time. Changing the mechanics of the substrate affects phagocytosis. Very interesting paper! www.cell.com/iscience/ful...

A crosstalk between adhesion and phagocytosis integrates macrophage functions into their microenvironment

Cell biology; Organizational aspects of cell biology; Specialized functions of cells; Functional aspects of cell biology

cell.com