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Lisa Beutler

@lbeutler.bsky.social

Doctor. Scientist. Dog mom.

195 Posts1852 Follower321 Folgt
Lisa Beutler@lbeutler.bsky.social · 2w ago

This is awesome. I did my MD/PhD at UW and can say that Dr. King is an inspiration and a force of nature. She was not a direct scientific mentor, but I can honestly say I continued doggedly on my career path in part because of her belief in me. If someone posts a link to the essay I’d be grateful.

Mark D. Garfinkel, Ph.D.@mdgarfinkel.bsky.social · 2w ago

Ali Velshi @velshi.com just gave a terrific video essay on the power of long-term curiosity-driven biomedical research — the kind of work DOGE & Trump & Vought are killing — using the career of Mary-Claire King as his example. Excellent commentary on @msnownews.bsky.social Eleventh Hour.

James Fallows@jfallows.bsky.social · 2w ago

Unlike my landsman @brianbeutler.bsky.social, I am old enough to be on Medicare. It works *so* much better than private insurance. So much less hassle for the patient. So much less overhead paid to insurance cos. So much more straightforward, like VA. Medicare For All (who want it) as the goal.

Brian Beutler@brianbeutler.bsky.social · 2w ago

I'm chiefly interested in defeating Republicans and holding criminals accountable. But if Democrats wanted to know how I'd go about waging factional war, I'd tell them their best bet would be to give the left a W on health care and open up Medicare to everybody. www.offmessage.net/p/medicare-f...

Timothy Snyder@timothysnyder.bsky.social · 2mo ago

In countries that have successfully reversed democratic backsliding in recent years—from Poland in 2023 to Hungary in 2026—opposition movements made prosecuting those who have broken laws a central campaign issue.

NPR@npr.org · 3mo ago

Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear. n.pr/4dwU7Fi

Researchers say the Trump administration is finding new ways to punish science

Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.

n.pr

Cell Reports@cp-cellreports.bsky.social · 4mo ago

GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits

GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits

Province et al. show that parabrachial CGRP neurons mediate aversion due to interleukin-1β (IL-1β) administration. Glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism blocks aversion and CGRP activation caused by IL-1β while potentiating its anorectic effect. Dorsal vagal complex GIPR mediates anorexia due to GIPR agonism but may be dispensable for anti-aversion.

dlvr.it

Daniel Drucker@danieljdrucker.bsky.social · 5mo ago

Localization of the inflammation associated anti-aversive actions of GIPR agonism via sites distinct from those that suppress appetite in the DVC www.cell.com/cell-reports...

GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits

Province et al. show that parabrachial CGRP neurons mediate aversion due to interleukin-1β (IL-1β) administration. Glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism blocks aversion ...

cell.com

Jeremy Berg@jeremymberg.bsky.social · 5mo ago

There are many problems with this statement from Director Bhattacharya. (1) As @michaeldgreen.phd notes, applicants have no option to requests multi-year funding. An applicant may request a front-loaded budget with more funding in early years with justification (may or may not be approved). 1/6

Michael D. Green, PhD@michaeldgreen.phd · 5mo ago

Bhattacharya on multi-year funding: “Sometimes for early-career scientists what you need is a front-loaded grant because they’re building their lab and so they can’t wait until year two or three to get the money, so it’s scientifically justified,” When you apply you don’t get to request MYF…

Joshua Weitz@joshuasweitz.bsky.social · 5mo ago

The data also reinforce a message that should be clear: American leadership in science and medical research requires far more than getting across the line on top-line budget negotiations and will require continued vigilance to track how HHS treats applications and existing awards.

Lisa Beutler@lbeutler.bsky.social · 5mo ago

New work from the lab on how sickness reduces appetite. Turns out, it’s complicated :) We focused on a single inflammatory cytokine, IL-1b, and even that reduces appetite via multiple mechanism. Thanks to Nik Hayes for leading and sticking with this project and to everyone else who contributed!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 5mo ago

IL-1β engages distinct peripheral sensory circuits to suppress feeding across time https://www.biorxiv.org/content/10.64898/2026.02.23.707454v1

Jeremy Berg@jeremymberg.bsky.social · 6mo ago

To summarize: Most important Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified. He was part of an organized team working on this problem. He got lots of help. 11/14

ProPublica@propublica.org · 7mo ago

Few patients appeal a health insurance denial, but a little-known process that requires insurers and plans to seek an independent opinion can force insurers to pay for what can be lifesaving treatment. Here’s what experts say you need to know.

This Little-Known Appeal Could Force Your Insurer to Pay for Lifesaving Care. Here’s How to File It.

When a health insurer refuses to pay for your treatment, you may have the right to have the denial reviewed — and potentially overturned — by an independent provider. Here are six steps experts sugges...

propublica.org

Chris Morran@themorrancave.bsky.social · 8mo ago

When Hannah’s pharmacy began filling her tacrolimus prescription with a generic version, the lung transplant patient didn't know something very important: Months earlier, an FDA-commissioned study concluded that this generic was not equivalent to the brand drug -- and that her life was at risk.

Fighting for Breath: The FDA’s Lax Generic Drug Rules Put Her Life at Risk

Lung transplant patient Hannah Goetz’s life depended on the generic version of the critical drug tacrolimus. It was supposed to be equivalent to the brand-name medication — but the FDA doesn’t always ...

propublica.org