New article! I had the pleasure of collaborating (also with @fcocubillosr.bsky.social, Claudio Martínez & @litinice.bsky.social) on this work, led by Dr Francisco Salinas, investigating the genomic structure of a horizontally acquired region (Region B) in #yeast. academic.oup.com/mbe/article/...

Genetic background shapes the transcriptional activity and phenotypic contribution of a horizontally acquired region in yeast

Abstract. Horizontal Gene Transfer (HGT) is the movement of genetic material across species. In Saccharomyces cerevisiae, a DNA segment known as Region B w

academic.oup.com

❗Latest review article out in the Yeast journal: Bingyin Peng, Masahiro Tominaga, Chengqiang Wang, Robert E. Speight and Jun Ishii discuss the latest advances in the usage of #transposons as tools for genome engineering in #yeasts and filamentous #fungi 🍄🍄🍄 👇 onlinelibrary.wiley.com/doi/10.1002/...

Transposons as Tools for Future Genome Engineering in Yeasts and Filamentous Fungi

Applications of transposon-based tools for genome engineering in fungi include transposon-mediated mutagenesis and targeted genomic integration.

onlinelibrary.wiley.com

❗New research article out in #Yeast: Tomoo Ogata, Katsuaki Kuroki and team study the mechanisms of mating-type-specific gene expression in miso and soy sauce Zygosaccharomyces species, with a special focus on the transcription factor Mata2 🍜 🍶 onlinelibrary.wiley.com/doi/10.1002/...

The new #Yeast issue of July 2026 (Volume 43, Number 4) is now out, with an editorial on the journal's history, two reviews on recent advances in optogenetics and synthetic biology, and two research articles about flocculation and new bioinformatic tools 🙂 onlinelibrary.wiley.com/doi/10.1002/...

Issue Information

No abstract is available for this article.

onlinelibrary.wiley.com

Ils « humanisent » la levure pour comprendre le cancer @litinice.bsky.social

New paper out: Alya Hussain, Kevin Fotso & @mcmurraylab.bsky.social describe #yeasts and other #fungi isolated from cacti or non-cactus plants, including the new species Coniochaeta udwismasis, and provide new hints at modes of #adaptation to the cactus 🌵🌵🌵 onlinelibrary.wiley.com/doi/10.1002/...

Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus

Yeasts and related fungi isolated from cacti or nearby non-cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host.

onlinelibrary.wiley.com

MichaelMcMurray lab@mcmurraylab.bsky.social · last mo.

Our new paper was, by definition, an adventure: stepping outside of our comfort zone, embracing the unknown, and engaging in activities where the outcome is uncertain. Includes discovery of a new species and working with a Native American tribe to name it… 🧵👇 onlinelibrary.wiley.com/doi/10.1002/...

Our new paper was, by definition, an adventure: stepping outside of our comfort zone, embracing the unknown, and engaging in activities where the outcome is uncertain. Includes discovery of a new species and working with a Native American tribe to name it… 🧵👇 onlinelibrary.wiley.com/doi/10.1002/...

Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus

Yeasts and related fungi isolated from cacti or nearby non-cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host.

onlinelibrary.wiley.com

In this #Yeast research article, Kanokarn Kocharin, Niran Roongsawang and team report the enhanced production of #recombinant thermophilic xylanase X11P in Ogataea polymorpha via in-silico signal peptide discovery and fed-batch #fermentation onlinelibrary.wiley.com/doi/10.1002/...

Enhanced Production of Recombinant Thermophilic Xylanase X11P in Ogataea polymorpha via In‐Silico Signal Peptide Discovery and Fed‐Batch Fermentation

Genome-wide signal peptide screening identified a novel Ogataea polymorpha α-mating factor-like peptide (FUN_005010) that markedly improved recombinant thermophilic xylanase X11P secretion. Combined ....

onlinelibrary.wiley.com

New article out for the series #technoYeast: Maria Abraham, Christine Iosue & Dennis D. Wykoff developed new molecular tools for genetic manipulation in the Nakaseomyces clade, that can be used for the #evolutionary comparison of signal transduction #pathways onlinelibrary.wiley.com/doi/10.1002/...

Genetic Tools in the Nakaseomyces clade for Evolutionary Comparisons of Signal Transduction Pathways

The genus Nakaseomyces provides four species that are closely related but have different characteristics. For example, N. glabratus (formerly known as Candida glabrata) is a common human pathogen, wh...

onlinelibrary.wiley.com

In this #Yeast research article, Koichi Tanabe, Atsuhiko Nakata, Mizuki Hosotani & Jun Shima investigate the role of organic acids in glucose repression by measuring GAR+ cells, which undergo a protein-based epigenetic change allowing them to survive longer. onlinelibrary.wiley.com/doi/10.1002/...

Sugar Metabolisms Altered By Undissociated Forms of Organic Acids Based on the Emergence of [GAR+] Cells in Saccharomyces cerevisiae

The glucose repression system is a mechanism for effective energy acquisition by glucose assimilation in microorganisms. In yeast, Saccharomyces cerevisiae, which is known as a prion-like protein [GA...

onlinelibrary.wiley.com

Interested in mitochondria? In this review article, Ferran Gómez-Armengol, Elena Hidalgo & Montserrat Vega discuss pros & cons of methods to study mitochondrial metabolism and homeostasis in fission yeast S. pombe, including in vivo and in vitro approaches. onlinelibrary.wiley.com/doi/10.1002/...

Methods to Study Mitochondrial Metabolism and Homeostasis in Fission Yeast

Click on the article title to read more.

onlinelibrary.wiley.com

Thank you for visiting @iamphioxus.bsky.social was great to see you again. I enjoyed both the science and the company and glad to see you are doing great. Come back soon 👋

Jia-Xing Yue (岳家兴)@iamphioxus.bsky.social · 2mo ago

Great to come back to Nice, an ever charming & cozy city that I’ve spent good five years of my life ! Had a lovely reunion with my postdoc advisor @litinice.bsky.social as well as both old & new friends at @ircan.bsky.social. Until next time, à bientôt ~

Not sure how to analyze your #rDNA data? Use rDNAmine, a new #bioinformatic toolkit for capturing and examining large repetitive arrays in Oxford Nanopore #sequencing data 🧬, by Agnieszka Czarnocka-Cieciura and Natalia Gumińska. Now published in #Yeast: 👇 onlinelibrary.wiley.com/doi/10.1002/...

rDNAmine: A New Tool for the Analysis of Long Repetitive Sequences

This work introduces a novel approach for analysing long repetitive genomic sequences, combining a method to isolate large DNA molecules from individual chromosomes. We also describe the bioinformati...

onlinelibrary.wiley.com

In this review, Audrey P. Gasch reflects on the history of the Environmental Stress Response (ESR) in #yeast, from its discovery 25 years ago to more recent insights into its purpose and regulation, focusing on remaining questions in #stress biology. onlinelibrary.wiley.com/doi/10.1002/...

Twenty‐Five Years of the Environmental Stress Response and the Enduring Power of Yeast in Stress Biology

All organisms must be able to sense and respond to adverse environments, especially those that threaten cellular integrity. The age of genomics clarified the breadth and specificity of cellular stres...

onlinelibrary.wiley.com

new lab preprint - Protein function prediction is a well established problem but proteins exist in different post-translationally modified forms. Here, @julianvangerwen.bsky.social built a ML model to predict the biological process regulated by individual phosphosites www.biorxiv.org/content/10.6...

It was a pleasure to share my research with the fission yeast community during the last #PombeTalks seminar and talk about our efforts to uncover the role of conserved unknown genes in S. #pombe and a new #mitochondrial gene that we discovered A big thank you to the organisers and the audience ☺️

In this editorial that marks #Yeast 's 40th anniversary, our former editor Stephen Oliver walks us through the journal's history, from its very first steps to the change of the editorial board in more recent years, and wishes the best for Yeast's future 🙂 onlinelibrary.wiley.com/doi/10.1002/...

Yeast at Forty

Click on the article title to read more.

onlinelibrary.wiley.com

In this review marking our 40th birthday, Edward Archer, Roy Walker, Paige Erpf, Ian Paulsen & Isak Pretorius reflect on the great power of #yeast #genetics, outlining key advances emerging from the Sc2.0 project and the future potential of #synthetic yeasts onlinelibrary.wiley.com/doi/10.1002/...

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome-scale engineering represents one of the most influential trajectories in euka....

onlinelibrary.wiley.com

Interested in #flocculation? In this #Yeast article, Devanshu Mehta, Mary Serviss, Keith Schneider, Renee Goodrich & Andrew MacIntosh investigate S. pastorianus flocculation during #brewing #fermentation, finding an association with the level of cell mannose onlinelibrary.wiley.com/doi/10.1002/...

The Role of Mannose in Saccharomyces pastorianus Flocculation During Industrial Brewing Fermentations

Yeast flocculation is a phenomenon in which yeast zymolectins bind to mannose on adjacent cells resulting in aggregation within fermentation media. Flocculation has been extensively studied and is of...

onlinelibrary.wiley.com

Another work on #optogenetics is out in #Yeast: in this review, Riya Joon, Rhythm Phutela & Prashant Khare discuss key advances in the field, with a focus on the EL222 system for protein production in P. pastoris and metabolic engineering in S. cerevisiae 💡💡💡 onlinelibrary.wiley.com/doi/10.1002/...

EL222‐Based Optogenetic Gene Regulation in Methylotrophic Yeasts: Mechanisms, Applications, and Future Directions

Methylotrophic yeasts such as Pichia pastoris are widely used for heterologous protein production because they contain strong and tightly regulated promoters. However, the use of methanol as an induc...

onlinelibrary.wiley.com

The new issue of #Yeast is out (Volume 43, Number 3, May 2026). Scroll down to read more about genome engineering in non-conventional yeasts, #lifespan extension, a new web platform to explore gene conservation and a new set of #optogenetic switches 😀 onlinelibrary.wiley.com/doi/10.1002/...

Issue Information

No abstract is available for this article.

onlinelibrary.wiley.com

Join us in wishing a massive happy 100th birthday to the man who has inspired millions of people around the world to care about nature and look after our planet - the incredible Sir David Attenborough! 🎉

In the latest #Yeast research article, Matías Guerrero, Francisco Salinas and team developed new optogenetic switches based on the BcWCL1 photoreceptor. These systems improve light-controlled gene expression in S. cerevisiae, and versions with C-terminal deletions are the most performant 💡💡💡

Eduardo I. Kessi-Pérez@eikp11.bsky.social · 3mo ago

New article today in @yeast-journal.bsky.social! I had the pleasure of collaborating in this work (also with Dr Claudio Martínez), led by Dr Francisco Salinas, in which a new set of #optogenetic #switches was developed in #yeast. onlinelibrary.wiley.com/doi/10.1002/...

The latest #Yeast research article features a tool developed by Guo-Song Jia, @lilindu.bsky.social & team: www.sogweb.org. Based on genome assemblies and annotations of Schizosaccharomyces species, users can explore gene alignments and phylogenetic trees. 👇 onlinelibrary.wiley.com/doi/10.1002/...

Schizosaccharomyces Orthogroup (SOG) Resource: A Web Platform for Exploring Gene Conservation in Fission Yeasts

The Schizosaccharomyces orthogroup (SOG) resource is a freely accessible web platform for fission yeast comparative genomics. It enables visualization of orthogroup alignments and phylogenetic trees,....

onlinelibrary.wiley.com

In the latest #Yeast research article, Yukinori Ozaki, Taku Ozaki and Qiu-Mei Zhang-Akiyama show that glucose restriction extends chronological #lifespan in budding yeast, while auxotrophic markers can induce abnormal cellular states under starvation. 👇 onlinelibrary.wiley.com/doi/10.1002/...

Glucose Restriction Extends Chronological Lifespan of Budding Yeast by Avoiding Commonly Used Auxotrophic Marker Nutrient Starvation

The survival period of yeast is determined by the type of nutrients they starved of. GR extends lifespan by avoiding auxotrophic starvation. Auxotrophic starvation causes degenerative cellular charac...

onlinelibrary.wiley.com

I am extremely happy to share that the final paper from my PhD in @litinice.bsky.social 's team at @ircan.bsky.social (Université Cote d'Azur, @cnrscotedazur.bsky.social) is now out in @natcomms.nature.com !!! 😁😁😁 👇 www.nature.com/articles/s41...

The new #Yeast issue of January-March 2026 (Volume 43, Number 1-2) is now out, with a review on the role of Rad9 in DNA repair, and three research articles spanning the isolation of yeast species from flowers and honeys, and the effects of furanic compounds. onlinelibrary.wiley.com/doi/10.1002/...

Issue Information

No abstract is available for this article.

onlinelibrary.wiley.com

In our recent study, we created over 1000 intraspecific yeast hybrids by crossing genetically diverse strains and tested how well they grow under harsh industrial conditions such as high ethanol, salt, and organic acids. enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

Influence of Ploidy and Genetic Background on Stress Tolerance of Intraspecific Yeast Hybrids

A large set of intraspecific yeast hybrids was constructed using two strategies that yielded series of hybrids with variable ploidy. Phenotyping of the hybrids was carried out in high-stress media to....

enviromicro-journals.onlinelibrary.wiley.com

In this #Yeast review article, Wendel Batista da Silveira & team give us an overview of the application of the CRISPR/Cas9 system in oleaginous yeasts. They discuss the main advances in the use of the tool, its technical limitations and future opportunities 🧬 onlinelibrary.wiley.com/doi/10.1002/...

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

Given the biotechnological potential of yeast-derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools su...

onlinelibrary.wiley.com

In this #Yeast research article, Laise Cedraz Pinto Matos, Amy Milburn and @yorkyeast.bsky.social investigated the physiological effects of #furanic compounds from the Maillard reaction in yeast & found that they have different uptake, efflux, and toxicity. onlinelibrary.wiley.com/doi/10.1002/...

Uptake Mechanisms and Physiological Effects of Furanic Compounds From the Maillard Reaction in Budding Yeast

Matos et al. use genetic approaches in Saccharomyces cerevisiae to show toxicity of different furanic compounds can be modulated via regulation of surface nutrient transporters. Distinct furanic comp....

onlinelibrary.wiley.com