Lee Zamparo
@lzamparo.bsky.social
Interested in ML, comp bio, immunology, and just about anything one hop away.
"Hydro corridors for kilometers in every direction" eh? I must have missed the hydro corridor running east west through the city so people can get to where they want to go. Also the corridor(s) running north south to where people work, study, shop. Do people genuinely believe this nonsense?
Matt Elliott@graphicmatt.com · yesterdayBradford also does the bike-lanes-belong-on-side-streets thing. Would be great if proponents of this kind of thinking could show us a map. Which streets? How do they lead to a cycling network that’s actually useful? Aren’t a lot of the places that cyclists want to get to on main streets?
I believe the removal promise, but not the "build something else" promise. Pass.
Matt Elliott@graphicmatt.com · yesterdayMayoral candidate Brad Bradford makes it official: he’d remove the Bloor West bike lanes if he wins in October.
Looks like a huge joint effort that will have a "rising tide" effect on so many research questions. Bravo to everyone involved!
Quaid Morris@quaidmorris.bsky.social · 5d agoExcited to share the results of the Codebook Project, an international effort to identify accurate DNA-binding motifs and genomic binding loci for >300 uncharacterized human transcription factors (TFs) www.nature.com/articles/s41...
Excited to share the results of the Codebook Project, an international effort to identify accurate DNA-binding motifs and genomic binding loci for >300 uncharacterized human transcription factors (TFs) www.nature.com/articles/s41...
An expanded codebook of human transcription factor DNA-binding specificity - Nature
Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative human transcription factors.
nature.com
Finally!
Toronto Cycling and Pedestrian Projects@cyclingpedestrian.cityof.toronto.ca · 6d agoThe West Toronto Railpath between Ernest Avenue and Bloor Street West has reopened following realignment to accommodate the Bloor GO/UP Station Improvements Project. Perth Avenue to Dundas Street West will close for construction in 2026. Learn more at toronto.ca/westrailpath.
Worm ppl have had this for years, and when I first found out about that it blew my mind. This is more astounding still
Jay Shendure@jshendure.bsky.social · 2w agoThrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote 1/n
Some initial thoughts, and a complicated mix of feelings. Wow. I mean, Erdos problems are cool (I genuinely mean that), I didn't know about the Jacobian conjecture before it got disproved. But this newest batch from OpenAI hits home in a way the previous announcements did not.
New preprint from Shendure Lab on Locus-Scale aka Long-@$$ MPRAs led by the amazing Abby McGee & @carinabiar.bsky.social Most MPRAs test ~300 bp fragments next to a promoter. But real enhancers are bigger, act combinatorially and from a distance. 1/n www.biorxiv.org/content/10.6...
great name, great topic for a workshop
ICBINB-BIO@icbinbbio.bsky.social · 3w ago🧬 We’re excited to announce the NeurIPS 2026 workshop, I Can’t Believe It’s Not Better: Failure Modes of AI in Biology (ICBINB-BIO), to be held in Sydney, Australia, on Dec. 11 or 12, 2026! 📣 We welcome full and tiny papers sharing challenges in developing AI models for biological tasks. (1/n)
Grateful to be working with Maria Brbić, Peter Koo @pkoo562.bsky.social, and Bianca Dumitrascu @bimidu.bsky.social on this exciting NeurIPS workshop, together with our incredible student organizers: Siba Smarak Panigrahi, Masayuki Nagai, Özgür Yılmaz Beker, and Soham Gadgil @sohamgadgil.bsky.social.
ICBINB-BIO@icbinbbio.bsky.social · 3w ago🧬 We’re excited to announce the NeurIPS 2026 workshop, I Can’t Believe It’s Not Better: Failure Modes of AI in Biology (ICBINB-BIO), to be held in Sydney, Australia, on Dec. 11 or 12, 2026! 📣 We welcome full and tiny papers sharing challenges in developing AI models for biological tasks. (1/n)
You ever think about how all this is happening after Orban lost in Hungary
Olga Nesterova@onestpress.onestnetwork.com · 3w agoI guess Russian transfers stopped?
This. This is the correct, science-backed, responsible framing. Wish more news outlets did it like the CBC.
'Just stop burning fossil fuels.' Scientists stress that our smoky skies only have one true fix | CBC News
Smoky skies in Toronto have led to new scrutiny of government efforts to fight fires and manage forests. But scientists say the realistic way to tackle the smoke is fighting climate change itself.
cbc.ca
1/ Trump signed 50% tariffs on Canada today under Section 338 of the Tariff Act of 1930. Worth walking through the legal mechanics, the USMCA leverage play behind it, and what it costs.
As a non-profit org, I'm sure this means huge investments incoming for grass roots football for the host nations especially, right? Right?
Nick Ames@nickames82.bsky.social · 4w agoExclusive – Fifa smash revenue projections with $15bn haul from World Cup, largely down to secondary ticket/hospitality markets: www.theguardian.com/football/202...
"Special circumstances" ? The legislature only sat for ~65 days this year (the least since reliable records are available). Peel isn't that far away. Just go home. Same ppl who tell you school boards are irresponsible, who suggest insane tunnels + convention centres nobody needs, a jet for DF.
Isaac Callan@isaaccallan.bsky.social · 4w agoNEW: Two cabinet ministers and a parliamentary assistant based in Peel Region billed $50,000 between them for hotel stays in Toronto under rules designed for "special circumstances." The premier's office says they'll pay some of it back. #OnPoli globalnews.ca/news/1196587...
We appreciate the love ❤️ But limited engagement and few followers on Bsky makes some (not us!) question whether it's worth it Be sure to follow (and share with your ML friends!) if you want to see more updates from ICML!
Marc Lanctot@sharky6000.bsky.social · last mo.Wow, awesome! Massive thank you to the comms & PR team @icmlconf.bsky.social 🤩 ✅️ Multiple update posts per day ✅️ Posts with photos!! 📷 ✅️ Great use of hash tags #icml2026 ✅️ Schedule and QR links at the local mall ✅️ Setting the gold standard for academic Bluesky 👍 🙏
I would have said "Comte Figure-de-Poubelle", and "Conte Figura-di-Bidone". I can post this because BlueSky is a pedant's dreamland
Josiah Mortimer@josiahmortimer.bsky.social · last mo.Rounding up some translations of Count Binface that have been appearing in foreign press 🇷🇴 Romanian: Contele Tomberonez 🇫🇷 French: Comte Tête-de-Poubelle (bin-head, more accurate than bin-face) 🇮🇹 Italian: Conte Faccia-da-Bidone 🇪🇸 Spanish: "un hombre con un cubo de basura en la cabeza" (!) Cont...
Just a reminder that there's only about a week left to leave comments on the OMB proposal that will cripple federally funded research. Here's my attempt to convince you that you should, along with info on how to do so effectively.
Ars Technica@arstechnica.com · last mo.
I will literally follow any and all ML PhD students on this website, where you at
All of these can be true at the same time: 1) The suspension reversal was corrupt 2) No FIFA rules were violated (Art 27) 3) Art 27 is ridiculous 4) This is not nearly FIFA's most corrupt action 5) FIFA's history of corruption doesn't justify this corruption 6) The red card by VAR was BS
4/ Remember that flu vaccine that RFK Jr.’s FDA said they wouldn’t review and then, after immense backlash, reviewed again? Well, we got exciting news: An FDA advisory panel voted 9-0 to back Moderna's mRNA flu vaccine, mFlusiva.
Dubious. Leao had himself an insane game, created a ton of danger, hit the crossbar with what would have been goal of the tournament, and he's trashed on this garbage board?
John Muller@johnspacemuller.com · last mo.Spot the problem
Succinct, elegant piece by @danyaalraza.com and Braden Manns on what "dual practice" is and does. Where's the federal Minister of Health? This is a clear violation of the Canada Health Act. Don't look away. #Never51st isn't only about fighting against Trump's chaos. It's about fighting *for* us.
The Breakdown AB@thebreakdownab.bsky.social · 2mo ago“parallel private-payment systems do not reduce public wait times. They increase them by diverting scarce resources away from public systems.” #abpoli #ableg #cdnpoli edmontonjournal.com/opinion/colu...
Age-standardized cancer death rates fell from over 150 per 100,000 Americans in 1990 to less than 100 as of 2022. A one-third drop in just over 10 years. ourworldindata.org/grapher/canc...
Chad Loder@chadloder.dev · 2mo ago"We declared a War On Cancer in the 1970s and we have not made significant progress on treating cancer despite ever-increasing funding. It's a welfare program for academic labs" Bro what the FUCK are you talking about. The survival statistics do not bear this out even at first glance
The Dufferin bus lanes are an unjustly delayed triumph. Sufferin no more!
holy sh*t, STAT is not messing around "STAT does not know who the patient is. But given the patient demographics and the unusual nature of the application, STAT asked the White House whether the patient was President Trump" www.statnews.com/2026/06/23/e...
Eli Lilly gave extraordinary obesity drug access to a 79-year-old patient. Who was it?
Exclusive: STAT has learned that Eli Lilly and the FDA allowed a 79-year-old to gain extraordinary access to an experimental obesity drug through the agency’s “compassionate use” program.
statnews.com
Why is it that some days, you have zero useful ideas, and other days you get multiple really solid research ideas? What the hell, brain, pace yourself.