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Maria Viola

@mariafviola.bsky.social

Wanderer and macrophage enthusiast, working in Bonn @masslab !

29 Posts1443 Follower1106 Folgt
Maria Viola@mariafviola.bsky.social · 9mo ago

Delighted to share this! We identify gut #macrophages as key players in preventing dissemination of intestinal microbes in liver cirrhosis. Best collab with my partner in crime @lenasmets.bsky.social, featuring some stunning live imaging with @colindascheele.bsky.social 👇 gut.bmj.com/content/earl...

Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis

Background Bacterial translocation in cirrhosis can trigger infection and hepatic decompensation, leading to systemic inflammation, organ failure and increased mortality. These infections often origin...

gut.bmj.com

Nina Cabezas-Wallscheid@ninacabezas.bsky.social · last yr.

🔥NEW paper from our lab! Ever wondered how the metabolite/lipid composition of human bone marrow HSCs changes during differentiation,aging,AML? Check our work www.nature.com/articles/s41... driven by the brilliant Marialena & Maricarmen with Jörg! @mpi-ie.bsky.social @ethz.ch @natcellbio.nature.com

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology

Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

nature.com

Maria Viola@mariafviola.bsky.social · last yr.

Please check out this awesome tldr of our new preprint on micro- and nanoplastics and their effect on #macrophages and #metabolism ! So excited to share this with the world, let us know what you think ! #microplastics #nanoplastics

Mass Lab@masslab.bsky.social · last yr.

1/ 🚨 New preprint alert! 🚨 Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...

Maria Viola@mariafviola.bsky.social · 2y ago

Not ✨macrophages✨ but a characterisation of a rather elusive cell type in the human colon : mast cells! Congrats @hindhussein.bsky.social , I've been looking forward to this !

Hind Hussein, PhD@hindhussein.bsky.social · 2y ago

Intro time! I'm Hind, a mucosal #immunologist working in KU Leuven on mast cells in health and in gut disease. Speaking of, I can finally show what I have been working on for the last 4 years, ie characterizing human mast cells in layers of the colon via scRNAseq www.biorxiv.org/content/10.1...

Toufic Mayassi@touficmayassi.bsky.social · 2y ago

1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇 www.nature.com/articles/s41...

Spatially restricted immune and microbiota-driven adaptation of the gut - Nature

Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...

nature.com

Maria Viola@mariafviola.bsky.social · 2y ago

As my blatant tour of self-promotion continues.. macrophages are so much more than just cells that eat things! Yet, even the eating can be very cool. Here, we showed that macrophages in gut shape the nervous system, and this makes 💩 happen correctly in adulthood: www.nature.com/articles/s41...

Dedicated macrophages organize and maintain the enteric nervous system - Nature

Resident macrophages of the muscularis externa refine the enteric nervous system (ENS) early in life by pruning synapses and phagocytosing enteric neurons, and later switch to a neuro-supportive funct...

nature.com