Marie Loescher

@marieloescher.bsky.social

PhD student in cognitive neuroscience at the LNC2, ENS, Paris Interested in brain-(rest of)body interactions and the biological basis of subjectivity

We are launching Interoception Circle! A new seminar series on embodiment, psychophysiology & body-brain coupling 1st online talk tomorrow: “What Role for Interoception in Perception? Evidence from Heartbeat-Evoked Potentials” (Marie Loescher) 3 June, 12pm CEST. All welcome! 🔗 ace2lab.com/2581-2/

Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr

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SOLIDARITÉ AVEC LE ROJAVA ‼️ La révolution du Rojava est attaquée depuis plus d'une semaine par les forces de HTS du pouvoir de Al-Charra en Syrie, soutenues militairement par la Turquie, et avec l'aval des USA et des pays de l'UE. Rassemblons-nous en soutien ! 🧵⬇️

solidarité avec le rojava

More on the link brain-heart axis and sensorimotor function, relevant for BCI research 🤖: Different bodily rhythms are coupled with cortical regions at rest. Here we show that motor imagery triggers a decoupling of cardiac dynamics with motor cortex functional connectivity 🧠🫀 doi.org/10.1101/2025...

Imagined movement increases the segregation of brain-heart networks

Understanding the mechanisms of motor imagery, the mental simulation of movement without execution, is key for the development of neurotechnologies. For instance, for detecting covert motor intent in ...

doi.org

So happy this paper is now out in @plosbiology.org! We investigated whether fluctuations in MEPs can be explained by phasic influences from internal bodily rhythms, and whether this might happen independently per organ system. #interoception #neuroskyence

PLOS Biology@plosbiology.org · 9mo ago

How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT

Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.

After initially being place on the reserve list, my Academy Research Fellowship has now received a positive result from the Research Council of Finland 🥳 Next year I will be starting my own team where we will work on identifying new interoception-based treatment targets for mental health disorders!