Our new story on how FGF23 regulates the genome and how both FGF23 and PTH control #vitaminD in kidney is finally up after years of work. Available on #researchsquare preprint server while under review: www.researchsquare.com/article/rs-1... @uwmadison.bsky.social @uwmadisonnutrisci.bsky.social
ETV1 Couples Reciprocal FGF23 and PTH Signaling to Renal CYP24A1 Regulation
Active vitamin D [1,25(OH)2D3; 1,25D] synthesis is finely balanced in kidney proximal tubules by the catabolic enzyme CYP24A1 and anabolic CYP27B1. Fibroblast growth factor 23 (FGF23) and 1,25D lower ...
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