your starter pack for Single Molecule Genomics! Why you should do it (or not) - How you should do it. Collective effort with @vram142.bsky.social @stirlingchurchman.bsky.social @naltemose.bsky.social A Stergachis M Stadler W Greenleaf @embl.org rdcu.be/PmzSEV529GRa

📢 We’re hiring a Cloud Platform Engineer to drive FMI’s transition to a modern hybrid cloud architecture. Help build the infrastructure supporting 20 research groups, advanced technology platforms and large-scale biomedical data analysis. Apply by August 31 at www.fmi.ch/education-ca...

📣 Call for Late-Breaking Poster Abstracts – EuroBioC2026 If you missed the earlier poster submission deadline, you can now submit your work as a late-breaking poster for EuroBioC2026. 📝 Submit by: Thursday, April 30, 2026 🔗Submit here: docs.google.com/forms/d/e/1F... #EuroBioC2026 #Bioconductor

We have an opening in our team! See the link below if you are interested:

FMI science@fmiscience.bsky.social · 8mo ago

💫 We're hiring! The Computational Biology Facility is looking for a Computational Proteomics Scientist to collaborate on cutting-edge proteomics projects, develop new analytical approaches, and publish impactful research. Apply by April 12 at: www.fmi.ch/education-ca...

🚀 EuroBioC2026 – Call for Abstracts is Now Open! We invite submissions for short talks, posters, and workshops for EuroBioC2026 by Jan 30, 2026. 👉 Submit here: openreview.net/group?id=bio... ⚠️ Note: Register on OpenReview at least two weeks before the abstract deadline to be able to submit.

🧬 EuroBioC2026 is coming to Turku, Finland, from June 3–5, 2026! Expect 3 exciting days with the Bioconductor community, showcasing the latest advances in Bioconductor software and emerging technologies shaping computational biology. 👉 More details soon at eurobioc2026.bioconductor.org

I think this is a beautiful example of evolution having come up with a simple and elegant solution to a complex gene regulation task!

Grosshans Lab@labgrosshans.bsky.social · last yr.

Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n

📣The Turco group is seeking a computational biologist to analyze large omics datasets. Work on cutting-edge 3D organoid models of the human placenta and be embedded in our Computational Biology Platform (part of @sib.swiss). Apply here: www.fmi.ch/education-ca...

🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

🙏 A big thank you to the Liberali Lab, FMI community & the FAIM imaging platform for testing and giving valuable feedback - keeping ez_zarr sharp, fast & useful! (3/3)

From spatial sequencing data to 5D images & high-throughput plate screens, ez_zarr helps you navigate images & labels quickly. If you work with NGFF OME standards, give it a try — and let us know what features you’d like to see next 💡(2/3) 📚 Docs: fmicompbio.github.io/ez_zarr/

We’re excited to share that ez_zarr now supports Zarr v3! 🚀 Huge thanks to @mbstadler.bsky.social & @csoneson.bsky.social who took on the challenge of creating this open-source tool for fast, programmatic access to OME-Zarr file sets + easy plotting 📊 📄 joss.theoj.org/papers/10.2110… (1/3)

ez-zarr: A Python package for easy access and visualisation of OME-Zarr filesets

Barbiero et al., (2025). ez-zarr: A Python package for easy access and visualisation of OME-Zarr filesets. Journal of Open Source Software, 10(109), 7882, https://doi.org/10.21105/joss.07882

joss.theoj.org

📝 New blog post: Bioconductor and ggplot2 4.0.0 - What’s Changing and How to Prepare A major ggplot2 update is coming and may impact Bioconductor packages. What’s changing, how to test, and where to get help 👉 blog.bioconductor.org/posts/2025-0... #Bioconductor #RStats

Bioconductor and ggplot2 4.0.0: What’s Changing and How to Prepare – Bioconductor community blog

Preparing for the upcoming update - key changes, potential breakages, and what developers and users can do

blog.bioconductor.org

🎓 Sharpen your RNA-seq skills at EuroBioC2025 Workshops! 📍 Barcelona | Bulk & Single-cell RNA-seq 📅 Sept 15–16 | Hands-on training 🎟️ Limited spots. Register now: eurobioc2025.bioconductor.org #Bioinformatics #EuroBioC2025

📣 EuroBioC2025 Registration is Open! 🎉 📍 Barcelona, 17–19 Sept 2025 Join us for keynotes, talks, workshops & more on open-source bioinformatics & Bioconductor. 🔗 eurobioc2025.bioconductor.org/pages/regist... #EuroBioC2025 #Bioinformatics

registration – EuroBioC2025

The budget EuroBioC2025 is conceived to break even after the conference. As a result, the organization of the EuroBioC2025 is unable to offer individual refunds.

eurobioc2025.bioconductor.org

If you look for an easy way to plot OME-zarr images in your scripts, I hope the ez-zarr python package will be useful:

Journal of Open Source Software@joss-openjournals.bsky.social · last yr.

Just published in JOSS: 'ez-zarr: A Python package for easy access and visualisation of OME-Zarr filesets' https://doi.org/10.21105/joss.07882

Eleven (!) quick tips for writing a Bioconductor package from @csoneson.bsky.social et al. from @fmiscience.bsky.social journals.plos.org/ploscompbiol...

Eleven quick tips for writing a Bioconductor package

journals.plos.org

Researchers led by @marcbuhler.bsky.social @merleskribbe.bsky.social @mbstadler.bsky.social @csoneson.bsky.social shed light on how transcription factors control genes in fission yeast—plus, they created FMI TFexplorer, a free tool for scientists! @pombase.bsky.social www.fmi.ch/news-events/...

Charting gene secrets: New insights into genetic switches

Gene regulation underpins nearly every biological process—from cell development to responses to environmental changes, and understanding it can provide insights into cancer and other diseases. Now, FM...

fmi.ch

www.sciencedirect.com/science/arti... I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬 Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌

A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin

Transcription factors (TFs) are key regulators of gene expression, yet many of their targets and modes of action remain unknown. In Schizosaccharomyce…

sciencedirect.com

Btw this is an actual movie, shot with a Canon DSLR in a photo studio incubator, of fluorescence-expressing plasmids competing and segregating inside cells

Michael Baym@baym.lol · 2y ago

Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!

📣 EuroBioC2025: Abstract Submissions Open! Join us in Barcelona, Spain 🇪🇸, Sep 17-19, 2025, for the European Bioconductor Conference! Submit your abstract for a short talk, workshop, or poster by Apr 24. ➡️ Submit https://buff.ly/3EN9w6P #EuroBioC2025 #Bioinformatics #RStats #DataScience

European Bioconductor Conference 2025

EuroBioC2025 is the European edition of the Bioconductor conference that will take place on September 17th to 19th, 2025, in Barcelona, Spain. EuroBioC2025 will bring together the Bioconductor…

buff.ly

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...

Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration

Tissue regeneration relies on the ability of cells to undergo de novo patterning. While tissue patterning has been viewed as the transition from initially identical un-patterned cells to an arrangemen...

biorxiv.org

Permanent position for a Linux Systems Engineer: Are you fond of scientific computing and/Linux/HPC and would enjoy working in a vibrant research environment? Have a look at our job opening: www.fmi.ch/education-ca...

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

Bioconductor 3.20 is released! 🎉🌟 Thanks to all developers and community members for contributing to the project! 🙌 👉 See the full release announcement: bioconductor.org/news/bioc_3_... #Bioconductor #DataScience #Bioinformatics #OpenSource