Megan Kirchgessner, PhD

@megkirch.bsky.social

🧠 scientist in NYC. NIDCD K99 fellow in Froemke lab @NYUmed. audition👂2P imaging 🔬and developmental systems neuro 👶. Prev: Simons Jr Fellow, UCSD NGP. Stories of WiN co-founder/director, marathon runner, foodie, IPA lover, and overly enthusiastic dog mom

It was such a joy to write about @binxuwang.bsky.social for @storiesofwin.bsky.social ! Really loved her story of her journey into neuroscience from physics, and looking forward to following her work as she entires an exciting new chapter of her career!!

Stories of WiN@storiesofwin.bsky.social · 4w ago

Our next profile is here! Dr. Binxu Wang (@binxuwang.bsky.social) studies how representations are generated in the brain and in AI models. Follow the link below to learn more! #StoriesOfWiN #WomenInNeuroscience www.storiesofwin.org/profiles/202...

We're excited to share our latest profile! Dr. Suzanne Haber studies the circuits underlying reward-based learning & decision making, and how those circuits can be therapeutically targeted to treat disease. Follow the link below to learn more! #WomenInNeuro www.storiesofwin.org/profiles/202...

Dr. Suzanne Haber — Stories of WiN

studies the circuits underlying reward-based learning and decision making, and how those circuits can be therapeutically targeted to treat disease

storiesofwin.org

I’ve had the pleasure of getting to know Carol over the last few years through the Simons SoF, so it was a particular joy to interview and write about her for Stories of WiN! I deeply admire her scientific contributions as well as her mentorship and leadership - we talked about all that and more!

Stories of WiN@storiesofwin.bsky.social · 3mo ago

Our latest profile is here! Dr. Carol Mason (@carolannmason.bsky.social) studies the development of connectivity between the eyes and the brain. Click the link below to listen and learn more! www.storiesofwin.org/profiles/202... #StoriesOfWiN #WomenInNeuroscience

Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!

Astrocytes connect specific brain regions through plastic networks - Nature

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

nature.com

Check out our new profile! Dr. Anila D'Mello (@aniladmello.bsky.social) studies language and cognition, and how the underlying brain circuits are altered in neurodevelopmental disorders. Follow the link below to learn more! #WomenInNeuroscience #StoriesOfWiN www.storiesofwin.org/profiles/202...

Dr. Anila D'Mello — Stories of WiN

studies language and cognition, and how the underlying brain circuits are altered in neurodevelopmental disorders

storiesofwin.org

📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!

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I had a great time talking to Meenakshi about my trajectory through neuroscience! Tune in for electric fish, imaging the hypothalamus, and trying to find a path in theory that stays relevant to the brain. Also, my early phd experiences of trying to do science when real life rears its head.

Stories of WiN@storiesofwin.bsky.social · 5mo ago

We apologize for the delay but our next profile is here! Dr. Ann Kennedy (@antihebbiann.bsky.social) combines theory & biological data to study how internal states shape social behavior by reconfiguring neural circuit dynamics. Follow the link to learn more! www.storiesofwin.org/profiles/202...

My travel to Cosyne was barred by the Trump admin, so I'm here on my personal dime. I care about the COSYNE community, I committed to co-chairing. And I always learn here. But the worst part about this travel ban is my lab colleagues— students and fellows—couldn't come. /1

Excited to be in Lisbon for my first #cosyne26 and to present TONIGHT on my work on developmental changes to spectral tuning and vocalization processing (and their interactions) in the postnatal auditory cortex! Poster 1-167, come to learn more or just to see me fight through the jet lag!

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Edvard I Moser@edvardmoser.bsky.social · 5mo ago

Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...

I’m so honoured to be featured in Stories of WIN this month - sharing my career journey and how storytelling changed everything for me! 🧪🎙️

Stories of WiN@storiesofwin.bsky.social · 5mo ago

Happy #WomensHistoryMonth! Thank you for helping us appreciate women in neuro & their stories! We believe in the power of storytelling, & our latest profile highlights Dr. Paula Croxson (@paulacroxson.bsky.social) who made science communication her career. Enjoy! www.storiesofwin.org/profiles/202...

Had a blast talking to @doctheagrif.bsky.social and writing her profile! We talked about her spark for neuroscience, her awesome research on sensory physiology and proprioception, her additional work as a prolific children’s book author, highs and lows of her journey, and more!

Stories of WiN@storiesofwin.bsky.social · 6mo ago

Our latest profile is here! Dr. Theanne Griffith (@doctheagrif.bsky.social) studies molecular, cellular, and circuit mechanisms for proprioception. Follow the link below to listen to our full interview! www.storiesofwin.org/profiles/202... #WomenInNeurosciene #StoriesOfWiN

Where does learning through imitation happen in the brain? In juvenile zebra finches, we pinpoint a synaptic locus of song learning in a cortico-basal ganglia circuit and leverage this localization to measure the timescale of consolidation and make birds learn faster! #neuroskyence (1/14)

A synaptic locus of song learning

Learning by imitation is the foundation for verbal and musical expression, but its underlying neural basis remains obscure. A juvenile male zebra finch imitates the multisyllabic song of an adult tutor in a process that depends on a song-specialized cortico-basal ganglia circuit, affording a powerful system to identify the synaptic substrates of imitative motor learning. Plasticity at a particular set of cortico-basal ganglia synapses is hypothesized to drive rapid learning-related changes in song before these changes are subsequently consolidated in downstream circuits. Nevertheless, this hypothesis is untested and the synaptic locus where learning initially occurs is unknown. By combining a computational framework to quantify song learning with synapse-specific optogenetic and chemogenetic manipulations within and directly downstream of the cortico-basal ganglia circuit, we identified the specific cortico-basal ganglia synapses that drive the acquisition and expression of rapid vocal changes during juvenile song learning and characterized the hours-long timescale over which these changes consolidate. Furthermore, transiently augmenting postsynaptic activity in the basal ganglia briefly accelerates learning rates and persistently alters song, demonstrating a direct link between basal ganglia activity and rapid learning. These results localize the specific cortico-basal ganglia synapses that enable a juvenile songbird to learn to sing and reveal the circuit logic and behavioral timescales of this imitative learning paradigm. ### Competing Interest Statement The authors have declared no competing interest. National Institutes of Health, K99 NS144525 (DCS), F32 MH132152 (DCS), F31 HD098772 (SB), R01 NS099288 (RM), RF1 NS118424 (RM and JP)

biorxiv.org

We're excited to share our next profile! Dr. Carla Shatz is a pioneering neuroscientist whose work reveals how early neural activity sculpts developing brain circuits & informs our understanding of neuroplasticity & neurodegenerative disease. Learn more below! www.storiesofwin.org/profiles/202...

Dr. Carla Shatz — Stories of WiN

studies how early neural activity sculpts developing brain circuits and informs our understanding of neuroplasticity and neurodegenerative disease.

storiesofwin.org

Well it’s been quite a year 🫠 but I’m happy and tremendously grateful to close it out on a personal science high-note - Ill be going to my first ever Cosyne, and I officially received the NOA for my K99/R00 from NIDCD 🙏 thank you Santa ie hardworking NIH staff for the best possible holiday gift 🥹

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