#פידמדע ישראלים מדענים ואקדמאיים בחו״ל, נקבע המועד לעשרות כנסים בארץ: 25-26 לאוקטובר. הרשמה תיפתח בימים הקרובים: www.mind-il.org
Orna Issler
@ornaissler.bsky.social
Neuroscientist, feminist, mom Assistant Professor NYU Grossman School of Medicine Non-coding RNAs, stress, depression, sex differences, chronic pain www.theisslerlab.org
🧠🧬 Our paper is now published in the Journal of Neurochemistry 🎉 dx.doi.org/10.1111/jnc.... During the review process, we received *exceptional guidance* from one of our reviewers, which led us to improve not only our paper, but the general Brain Data Alchemy analysis pipeline. Thank you! 🙏💛
The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta‐Analysis of Public Transcriptional Profiling Data From the Hippocampus and Cortex
Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We us....
dx.doi.org
🧠🧬 We still don’t know how antidepressants *actually* work. Why does depression respond to treatments as diverse as SSRIs, TCAs, electroconvulsive therapy, TMS, tianeptine, and ketamine? What do these treatments have in common? (hint: not serotonin) See our new preprint! doi.org/10.1101/2025...
🚨Applications are now open for our S.P.i.N.E.S. Postdoc Seminar Series 2026/2027! Deadline August 15th. Find all info and link to the application here: med.nyu.edu/departments-...
New paper out online today!! We identify two previously unrecognized transcripts at the BDNF locus, BDNF-DT and BDNF-AS-DT, that are developmentally regulated, coordinated with BDNF expression, and associated with schizophrenia risk. www.nature.com/articles/s41...
BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus - Molecular Psychiatry
Molecular Psychiatry - BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus
nature.com
The entire NSF budget is less than what we spent in the first week of the war with Iran. The NIH accounts for a fraction of 1 percent of all federal spending. www.nytimes.com/2026/06/20/o...
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
nytimes.com
A great stretch for the issler lab! ✅ First NIH funding ✅ First conference sharing our data ✅ First departmental seminar We are on a roll!
Who knew that three letters could make me so happy! N o A
As an anthropologist, I endorse this message!
I have a new essay up today on how the brain changes with second-time motherhood, featuring research by the @pregnancybrainlab.bsky.social
Happy to share our new review on Neural Mechanisms of Social Hierarchy across Species. We discussed different routes to achieve high social status across species, from fish to humans, and the neural circuits that support each of those strategies. www.nature.com/articles/s41...
Neural basis of social hierarchy across species
Nature Reviews Neuroscience - Structured social hierarchies, in which individuals differ in their access to resources and influence over other group members, are a characteristic of many social...
nature.com
Sounds super interesting - hope we'll see more of these (lncRNAs linked by human genetics + mouse KOs to key phenotypes)! www.nature.com/articles/s41...
An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism - Nature
PTCHD1-AS, which encodes a long non-coding RNA, is associated with the aetiology of autism spectrum disorder in humans through striatal molecular and circuit-level dysregulation.
nature.com
Hiring! Please share! Two postdoctoral researchers at EPFL, Lausanne, to join an SNSF-funded project on stress, motivation, immersive VR, physiology, multimodal sensing and translational biomarkers. Details & applications: www.fens.org/careers/job-... www.fens.org/careers/job-...
Postdoctoral Researcher in Multimodal Human Sensing and Advanced Behavioral Data Analysis - Federation of European Neuroscience Societies
fens.org
🧠🧪 join us here at the vibrant UC Irvine. Any career level. Great science, collaborative folks, and the weather is tolerable🤗. Please amplify @thebalelab.bsky.social @cate-cholamine.bsky.social @mayoonthebrain.bsky.social @karenswilcoxphd.bsky.social @acnporg.bsky.social @heydrdukes.bsky.social
2/6: In January 2025 we launched this new Institute (depressioninstitute.uci.edu), with the vision to transform our understanding of depression’s origins, treatment, and prevention, while enhancing societal-well being.
Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!
Astrocytes connect specific brain regions through plastic networks - Nature
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.
nature.com
What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan. www.nature.com/articles/s41...
The neural mechanisms supporting the rise and fall of maternal aggression - Nature
In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically amplified by oxytocin during lactation.
nature.com
Highly recommended!
We are recruiting! My lab at the University of Haifa is looking for new team members to join our research on the links between sensory perception (focus on #smell and human #olfaction) and human memory. Please help me spread the word #newPI #academia #neurostuff
We are recruiting! My lab at the University of Haifa is looking for new team members to join our research on the links between sensory perception (focus on #smell and human #olfaction) and human memory. Please help me spread the word #newPI #academia #neurostuff
Professors: come get trained by us in how to teach the Night Science Workshop on the creative scientific process to your students who are thirsty for this material! Our Train-the-Trainer 1day program in NYC April 24 is in partnership with the NY Academy of Sciences! night-science.org/train-the-tr...
Deadline extend till April 14th! Please RT!
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
A reminder! Do not miss out on this opportunity!
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...
Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...
nature.com
Rallies tomorrow around the country! @standupforscience.bsky.social Find one near you. www.standupforscience.net www.wesa.fm/health-scien...
Pittsburgh 'Stand Up for Science' rally to bring attention to impacts of immigration crackdowns
The National “Stand Up for Science” day of action returns to Pittsburgh tomorrow for the second year in a row to protest government actions and policies affecting scientific institutions, research and...
wesa.fm
"Cross-Organ Neuroimmunology of Behavior". Xuanming Guo and I discuss a new framework that reconceptualizes behavior as an emergent property of a distributed, brain-body neuroimmune network. lnkd.in/eihqZ_ay. @sinaiimmuno.bsky.social @sinaibrain.bsky.social
New postdoctoral opportunity @lieberinstitute.bsky.social working w/ @tsawada1.bsky.social and our Molecular Neurogenetics team using human induced pluripotent stem cells to investigate molecular, cellular and neuroendocrine mechanisms by which impaired placental function impacts brain development
I am so proud to share @forrestdrogers.bsky.social’s postdoctoral magnum opus, now out in @nature.com! Forrest discovered a novel role for Agouti in the MPOA of the hypothalamus to integrate socio-environmental information to flexibly tune paternal behavior www.nature.com/articles/s41... Thread! 👇🏻
Agouti integrates environmental cues to regulate paternal behaviour - Nature
Expression of agouti signalling protein in neurons in the medial preoptic area is increased by group housing and negatively associated with care, and overexpression of Agouti reduces care and enhances...
nature.com
Why are some males caring toward infants while others are neglectful or abusive? I'm so pleased to share work that my colleagues and I @princeton.edu have just published @nature.com (an explanatory thread to follow!) (1/8)
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
Very excited to get to share culmination of this large-scale project to understand spatial gene expression in schizophrenia. Really proud of the amazing team work here working out lots of roadblocks to deploy these spatial strategies and analysis methods at scale!
FIRST post here on Bluesky - we’re excited to share that our large spatial transcriptomics study of the human dlPFC in schizophrenia is now available on bioRxiv📄: www.biorxiv.org/content/10.6... (1/9)