We face great challenges, but our resolve is greater & vision clearer for the future of neuroscience. The @young-pi-neuro26.bsky.social network is stronger than ever. Thanks co-organizers, speakers @tjryan.bsky.social, @drosostalis.bsky.social, @anne-schreiter.bsky.social, & our core ➡️ participants!

Outstanding new study tracking the changes in Purkinje neuron dendritic architecture during primate evolution, documenting an increase in dendritic compartmentalization in the human lineage Study by @auroraferrell.bsky.social @neurosilas.bsky.social & colleagues 🧪🧠 #cerebellum

Cerebellar Purkinje cells change dendritic architecture during primate evolution

Vertebrate evolution has driven adaptive remodeling of brain regions impacted by changing sensorimotor demands. The cerebellum--a hindbrain area mediating associative learning and predictive coding--i...

biorxiv.org

Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...

📢📢 Job opening between the Bioinformatics Unit and my group (REPBIO) at @crg.eu Interested in contributing to our efforts to leverage long-read sequencing technologies for human genome research? Join us in Barcelona: recruitment.crg.eu/content/jobs... Please repost😊

Amazing comparative study from @djabaudon.bsky.social lab between mus musculus and Acomys (spiny mouse) brain development!

Sergi Roig Puiggros@sroig.bsky.social · 2mo ago

Thrilled to shared our new preprint with @djabaudon.bsky.social ! Led by Ilaria Morassut, we explored "the extent to which early brain maturation requires interactions with the outside world". This wouldn't have been possible without our incredible collaborators, specially the @lanevol.bsky.social 🧵

Loving this new preprint -- such a clever way to examine the question of the importance (or not!) of sensory experience in shaping cortical development. I wish we could have cited this in our discussion on altricial/precocial animals last year.

Sergi Roig Puiggros@sroig.bsky.social · 2mo ago

Thrilled to shared our new preprint with @djabaudon.bsky.social ! Led by Ilaria Morassut, we explored "the extent to which early brain maturation requires interactions with the outside world". This wouldn't have been possible without our incredible collaborators, specially the @lanevol.bsky.social 🧵

still fascinated by the barrel cortex

Sergi Roig Puiggros@sroig.bsky.social · 2mo ago

We demonstrate that the prenatal conservation of this programs, supports a prenatal establishment of functional circuits, which in turn are essential to execute sensorimotor behaviors linked to late-postnatal stages in mus.

Excellent new preprint by @sroig.bsky.social @djabaudon.bsky.social & collaborators on the prenatal assembly of functional cortical circuits. Great discussion of maturation www.biorxiv.org/content/10.6... 🧪🧠

Thrilled to shared our new preprint with @djabaudon.bsky.social ! Led by Ilaria Morassut, we explored "the extent to which early brain maturation requires interactions with the outside world". This wouldn't have been possible without our incredible collaborators, specially the @lanevol.bsky.social 🧵

🦈🧠2 JOB OFFERS in the brand-new Neuroshark group starting at the Institute of Neuroscience Paris-Saclay (NeuroPSI)? Lab manager: www.linkedin.com/posts/idoia-... Bioinformatician: www.linkedin.com/posts/idoia-... Curious about the lab but not your profile? Feel free to contact me

Lab manager job | Idoia Quintana Urzainqui

JOB OPPORTUNITY 🦈 🧠 🔬. We are looking for a Lab Manager to help establish a new group studying shark embryos to understand the origin of the vertebrate brain. Reach out if this motivates you. We’re ba...

linkedin.com

Registration is still open for the Young PI Neuroscience Symposium. Whether you're a young PI or a "seasoned" postdoc, you can never invest too much in building community; especially in, let’s say, turbulent times. If you have any questions, feel free to reach out.

Young PI Neuroscience Symposium'26@young-pi-neuro26.bsky.social · 5mo ago

We have got a great program. ⏰⏰Time to register to our @fens.org Satelite 👉 youngpisymposium2026.com

www.eurekalert.org/news-release...

Broad collaboration produces high-resolution atlas of developing human brain

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and the brain later in life, investigators at Johns Hopkins Medicine and collea...

eurekalert.org

Apply for a PhD position with us at @inmed.bsky.social and join @neuromarseille.bsky.social PhD program! Our proposed PhD project is about excitability change and #epilepsy in cortical malformations 🧠🔥🧪🎓 More details below 👇🏻 www.fens.org/careers/job-...

Relating to our recently published paper in @natneuro.nature.com! 🔥🚨 Find here a research briefing that we wrote w/ @djabaudon.bsky.social trying to reach a broader neuroscience audience! Enjoy the reading! www.nature.com/articles/s41...

Delighted to have contributed to this thorough and collaborative piece of work with amazing colleagues and friends! 🧠🚀

Sergi Roig Puiggros@sroig.bsky.social · 7mo ago

I'm very excited to finally see this one out in @natneuro.nature.com ! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n www.nature.com/articles/s41...

I'm very excited to finally see this one out in @natneuro.nature.com ! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n www.nature.com/articles/s41...

Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience

Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...

nature.com

Great @natneuro.nature.com study by @sroig.bsky.social @djabaudon.bsky.social @jbmanent.bsky.social & colleagues, showing “equivalent circuits can emerge in different spatial configurations, allowing diverse brain architectures to converge on similar functional outcomes” 🧪🧠🧬

Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience

Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...

nature.com

Very happy to have contributed to this wonderful/tentacular work alongside so many amazing colleagues and friends! It opens up new ways of understanding grey matter heterotopia associated with altered cortical function and #epilepsy in humans. 🧠🧪🔥 www.nature.com/articles/s41...

Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience

Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...

nature.com

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

Cell-extrinsic controls over neocortical neuron fate and diversity

Cell-extrinsic cues are key for neocortical cell identity and diversity.

science.org

Very happy to have contributed to this great story 🧠🚀. It focuses on environment-dependent neuronal identity acquisition in the cortex! Big congrats to Natalia Baumann, Ilaria Morassut and Sabine Fièvre for pushing this w/ @djabaudon.bsky.social. Congrats to all! www.science.org/doi/10.1126/...

Cell-extrinsic controls over neocortical neuron fate and diversity

Cell-extrinsic cues are key for neocortical cell identity and diversity.

science.org

Super lab looking for postdoc ... do not miss it! 👇🏼

Manuel Irimia@mirimiam.bsky.social · last yr.

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

How bats developed their wings? 🦇 Turns out they reutilize existing gene programs 🔧 Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs www.nature.com/articles/s41...

Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution

Single-cell comparison of developing bat and mouse limbs reveals conservation of cell populations and gene expression patterns, and suggests repurposing of genes involved in proximal limb development ...

nature.com

1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social @wellcometrust.bsky.social

A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons

Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α partners with ERRγ and Mef2c to ...

cell.com

Thrilled to co-chair Symposium S08: Developmental Origins of Astrocyte Diversity tomorrow at #GLIA2025! Join us for cutting-edge insights into how astrocytes are born , diversify, and shape brain function. Wed, July 9 | 🕙 10:00–12:00 With @loulierk.bsky.social , Maryam Faiz & @sloanlab.bsky.social

✨ Astrocyte diversity starts at the source! 🧬 We uncover how dual radial glia lineages generate distinct astrocyte subtypes in the neocortex — revealed by MERFISH, scRNA-seq & clonal tracing. 📍#GLIA2025 | Poster T10-010A 🧠 w/ @alanzhoujf.bsky.social in Marseille Come talk glia with us!

Now out in @natneuro.nature.com: Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice. Congrats to first authors @annrosebright.bsky.social, Yana Kotlyarenko, @flo-neuhaus.bsky.social, and thanks to all collaborators! www.nature.com/articles/s41... 1/n

Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience

Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...

nature.com

We're hiring! Our lab is looking for a postdoc to investigate the #evodevo of #cephalopod brains. Did you recently graduate, and do you want to join our EU #WEAVE project with the Simakov and @simon-sprecher.bsky.social labs? Find the application form👇Thanks for RT 🐙🦑 www.kuleuven.be/personeel/jo...

Postdoctoral researcher in evolutionary developmental neurobiology

Come join our EU cephalopod consortium to discover how octopuses and other coleoids developed their large nervous system. Postdoc position available in the Seuntjens Lab in Leuven, Belgium.

kuleuven.be

Very grateful to have been able to present our work at the @corticodevelopment.bsky.social meeting in Naxos! Thanks putting together such a great line of speakers in this amazing location! 🧠☀️🍕

Still openings, check it out!

Denis Jabaudon@djabaudon.bsky.social · 2y ago

🧠Job Opening!🧠 We are opening 2️⃣! positions – bioinformatics / molecular biology – in a project studying how temporal patterns set up connectivity in human brain tissue. @institutimagine.bsky.social. Full details below, contact me for details if interested. And please retweet (re-bluesky?)!

🎉 Excited to share that our paper on FCDII is out today! 🙌🏻 Huge thanks to @sbaulac.bsky.social and @sara baldassari for bringing me on board and introducing me to the complexity of somatic mutations. Hope our work helps advance understanding of the disease mechanisms.

Nature Neuroscience@natneuro.nature.com · last yr.

Single-cell genotyping and transcriptomic analysis reveals cell-type specific and non-autonomous effects of mTOR pathway mutations in mosaic focal cortical dysplasia type II (FCDII) 🧠🧪 www.nature.com/articles/s41...