mia
@miarosenfeld.bsky.social
machine learning drug discovery scientist @ iambic tx | neuralplexer developer computational biophysicist, glycoscientist, feminist, jewish, lover of sufjan stevens. she/they 🏳️🌈 ✡︎ 📍 sf/nyc
pls RT for reach! can’t wait to see y’all there 😁 @acs.org #CompChem
@acscomp.bsky.social · last yr.Mark your calendars for the ACS COMP *SUNDAY* Social on August 17, 2025! Free German 🥨&🍻 for COMP members, sponsored by OpenEye + Cadence 💻 RSVP link dropping soon in all ACS COMP members' email inboxes :)
Well the NIH has cancelled the Women's Health Initiative, the largest study of women in history It has been running continuously since 1991 and has provided massive key knowledge about diseases in women Unreal www.science.org/content/arti...
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
science.org
Register Now for Crash Course: Python For Cheminformatics-Driven Molecular Docking This free virtual course will demonstrate the power and flexibility of python on May 1, 2025 pdb101.rcsb.org/news...
PDB101: Register Now for Crash Course: Python For Cheminformatics-Driven Molecular Docking
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb101.rcsb.org
@fionachembot.bsky.social opened up linkedin to this, and honestly, i can't help but immediately see a mucin rendering next to this depressing news headline... 😂
People/organizations with means and a vision for the future of biomedical science - we need an “Arc Institute” equivalent in the DMV area to sponge up all the incredible talent, opportunity of a lifetime for a visionary entrepreneur, I will help! @mcuban.bsky.social
Read: OpenAI raised $40B—i.e., the entire NIH budget.
TechCrunch@techcrunch.com · last yr.OpenAI announced that it closed one of the largest private funding rounds in history. According to a blog post on the company’s website, OpenAI raised $40 billion in a round that values the company at $300 billion post-money. Read more here: tcrn.ch/4lbbzCf
If you love drug candidates but weren't able to attend the #FirstTimeDisclosures symposium at #ACSSpring2025, check out my story about the session for @cenmag.bsky.social - with lots of cool-looking molecules. cen.acs.org/acs-news/acs...
12 drug candidates debut in San Diego
Structures unveiled during first-time disclosures symposium
cen.acs.org
🚨 PLEASE RT 🚨 Are you a comp chem trainee attending Spring ACS in San Diego? Would you like to expand your network with mentors in industry & academia at the COMP Mentor Lunch? Fill out this form if you are interested in attending! forms.gle/Sq79TJihHnFW...
forms.gle
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Unassigned nitrogens in nmr data often indicate biologically relevant motion in proteins, and this can be used train deep learning models of protein dynamics! Hannah Wayment-Steele @ginaelnesr.bsky.social @sokrypton.org www.biorxiv.org/content/10.1...
This was a massive team effort and I'm forever grateful for the full list of authors helping me to drive this one into the endzone! Thank you to Anthony Bogetti, Carla Calvó-Tussell, @mackevinbraza.bsky.social, @lcasalino88.bsky.social, Amanda Gramm, Sean Braet, @miarosenfeld.bsky.social,... (1/2)
Dr. Fiona@fionachembot.bsky.social · last yr.Nevertheless, we persisted ❤️ 📣 NEW BIORXIV ALERT!! 🚨 Using WE MD, linguistic pathway clustering, dynamical network analyses, and HDXMS we reveal a hidden allosteric network within the SARS2 spike S1 domain and predict how the D614G mutation impacts this network! www.biorxiv.org/content/10.1...
thrilled I got to plan this year's ACS COMP social in my science home town 🌊♥️💻🧪 hope to see y'all there!!!
@acscomp.bsky.social · last yr.Mark your calendars for the ACS COMP Saturday Social on March 22, 2025! Free 🌮 & 🍻 for COMP members! If you didn’t get the RSVP link in your email inbox, DM us with a screenshot of your COMP membership and we’ll shoot you the RSVP link 😁 #ACSSpring2025 #chemsky
This stupid SOB is practically rooting for the measles virus. He will apparently do almost anything to avoid vaccination:
RFK Jr.: It Would Be Better if ‘Everybody Got Measles’
“The measles gave you lifetime protection against measles infection,” Robert F. Kennedy Jr. told Sean Hannity on Fox News.
thedailybeast.com
reality of ML+bio research: real methodological innovation is rare, expert application is common. & that's okay! most progress comes from skillfully using existing tools. lets be honest abt contributions & stop repackaging established methods with domain expertise as "novel computational frameworks"
What's easier to learn: cryo-EM or MD simulations? Ben Orlando and I couldn't decide, so we are accepting post-doc applications from both fields! Come work with us to explore the intersection between cryo-EM and MD at Michigan State! careers.msu.edu/jobs/researc...
Research Associate-Fixed Term - East Lansing, Michigan, United States
Position Summary A Postdoctoral Research Fellow position is available in the Department of Biochemistry and Molecular Biology (BMB) at Michigan State University. The fellow will work at the interface ...
careers.msu.edu
Mentioned in the below article, Science is running a "Trump tracker" that's attempting to keep up with the ongoing firings at scientific agencies within the US: www.science.org/content/arti...
Trump Tracker: Firings, lawsuits and U.S. science in chaos
Follow President Donald Trump’s impact on U.S. research and science globally
science.org
Derek Lowe@dereklowe.bsky.social · 2y agoHere’s the latest in the Continuing Crisis series - there will, unfortunately, be more:
@biophysicalsoc.bsky.social you need to be sharing at the conference this week like our lives depend on it. Because they do. Speak up. Stand up. Get out there and protect out democracy
Stand Up for Science!@standupforscience.net · 2y agoWelcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
If anyone has the resources to resist, its HHMI. Ending this program with no notice and literally scrubbing evidence it ever existed from the website is shocking and dosappointing
Viji@vijisathy.bsky.social · 2y ago
i’m hiring! come work with our amazing neuralplexer development team at iambic therapeutics to help increase the conformational accuracy of our protein structure predictions! pls share with folks you think may be interested, & feel free to reach out with questions jobs.ashbyhq.com/iambic-thera...
Graduate Research Intern - Machine Learning for Protein Structure Prediction
JOB SUMMARY We are seeking a graduate student for a research internship at Iambic Therapeutics to contribute to the development of NeuralPLexer, our protein structure prediction platform. This intern...
jobs.ashbyhq.com
An example of how the limited and biased availability of data narrows the range of functional biology PLMs tap into for prediction and design research.arcadiascience.com/pub/result-p...
The known protein universe is phylogenetically biased
Many protein prediction and design models rely on evolutionary comparisons. We show that popular databases are phylogenetically biased, influencing the statistical utility of the known protein univers...
research.arcadiascience.com
Seemay Chou@seemaychou.bsky.social · 2y agoAnother way to structure data is thru lens of evolution. People forget this was a key unlock for protein predictions (MSAs). There's not enough data/compute/$ for big AI promises without. Why I've devoted all my energy to old school, open evo tools @arcadiascience.com -- that's "big bio" IMO
move over ligand RMSD < 2 Å 😤 ConfBench is on the scene! if you're interested in the evaluation of conformational accuracy of structure prediction methods, take a look at our first stab at a systematic conformational benchmark in the NP3 technical report below! 🧵 www.iambic.ai/post/np3-tec...
Friends don't let friends make bad graphs repo has been updated! Friends don't let friends use boxplot for binomial (bimodal) data. Is your box plot hiding something from you? #DataVisualization github.com/cxli233/Frie...
Three BioML starter packs now! Pack 1: go.bsky.app/2VWBcCd Pack 2: go.bsky.app/Bw84Hmc Pack 3: go.bsky.app/NAKYUok DM if you want to be included (or nominate people who should be!)
SARS-CoV-2 NTD variants that escape host immunity possibly by introducing new epitope-blocking glycosylation sites #glycotime @cobarnes27.bsky.social
TRAstonDrs@castltrastondrs.medsky.network · 2y ago#MedSky🧪 #IDSky #Immunosky in this study the variant XEC exhibits extensive immune evasion, and its new NTD mutations, which may introduce new glycosylation, can cause potency reduction of anti-RBD antibodies, probably through allosteric effects @yunlong_cao www.thelancet.com/journals/lan...
@ my san diego comp chemists! december SAGIM event was announced! looking forward to connecting with fellow comp chemists and modelers over craft beers at new english brewery this december 5th - drop by between 4-7pm www.meetup.com/southern-cal...
December SAGIM Happy Hour, Thu, Dec 5, 2024, 4:00 PM | Meetup
Join us for a SAGIM happy hour at New English Brewery. Connect and network with other San Diego based computational chemists, modelers and informaticians working in biotech
meetup.com
Two BioML starter packs now: Pack 1: go.bsky.app/2VWBcCd Pack 2: go.bsky.app/Bw84Hmc DM if you want to be included (or nominate people who should be!)
Kevin K. Yang 楊凱筌@kevinkaichuang.bsky.social · 2y agoI tried to make a bioml starter pack. DM if you want me to add or remove you? go.bsky.app/2VWBcCd
