A new Science study shows that bumble bees can position a ball underneath a fake “flower” to reach a reward, suggesting they can exhibit spontaneous problem-solving and challenging the notion that such advanced cognitive abilities are exclusive to large-brained vertebrates. https://scim.ag/4vs08dC

We are very proud of our @uni-saarland.de B.Sc. student Smilla @smillakoy.bsky.social for winning the Euro #Cilia2027 image competition. A well-deserved recognition of her amazing work. We're lucky to have such talent in the lab!

EuroCilia2027@eurocilia.bsky.social · 2mo ago

🏆 GRAND PRIZE WINNER 🏆 Congratulations to Smilla-Maria Koy (BSc Student, Mick Lab, Saarland University, Germany) for winning our Image Competition! 🔬 "IMCD3 Spheroid with Cilia" captures primary cilia emerging into the lumen to show cell polarity. #FluorescenceFriday #Cilia #ConfocalMicroscopy

I am hoping that all companies who are selling antibodies will take this very seriously.

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

Please check this out! Great technical improvement. Congrats Bas and Helge!

Ewerslab@ewerslab.bsky.social · 3mo ago

New paper out! Left-handed DNA cannot bind to natural, right-handed DNA. This leads to lower background if it is used as a probe in DNA-PAINT. Using Fluorigenic DNA-PAINT with left-handed DNA allows for low background, fast 3D DNA-PAINT! Congrats, Bas! skeetorial: 1/x pubs.acs.org/doi/full/10....

Had a fantastic visit at our friends at the IFIB @unituebingen.bsky.social, where I presented our iAPEX technology and how we use it to study primary cilia dynamics. @for5547.bsky.social Fun discussion with the #biochemistry M.Sc. students after the talk and a lovely dinner. Thanks for the invite!

Finally got around to reading this fantastic work on in vitro reconstitution of plasmodium #microtubules, highlighting the importance of lattice interactions. Congrats all! It was a fun read.

Simone Reber@simonereber.bsky.social · 5mo ago

In vitro reconstitution is powerful: we can rebuild Plasmodium microtubule architectures from purified components and recapitulate what cells actually do 🤩 Thanks to an incredible team that made this possible 🙌 @carolynmoores1.bsky.social in particular rdcu.be/e7eM2

Also our froggies had a fantastic time at our @for5547.bsky.social retreat on primary #cilia dynamics. This one was amazed about all the discussions and progress in each single project. So many potential new research directions. Go team #xenopus! @walenteklab.bsky.social @kerstinfeistel.bsky.social

Great start of @for5547.bsky.social PI retreat with primary #cilia and 🌞😎

Exciting to see this out in its final form! Wonderful work led by @probablycarmen.bsky.social. Want to know why protrusions are better at initiating immune signaling in #Tcells? Look no further. Link to Carmen’s 🧵 on the preprint bsky.app/profile/prob...

The EMBO Journal@embojournal.org · 4mo ago

Revised role for actin-rich protrusions in T-cell activation: @franbottanelli.bsky.social @probablycarmen.bsky.social et al reframe them as sites of enhanced receptor activation by exclusion & clustering dynamics, rather than pre-enrichment of signaling components link.springer.com/article/10.1...

We'll be back for our @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social 56th e-symposium August 25th 2026- register: www.eventbrite.co.uk/e/bscb-genso... Sign-up to speak: forms.gle/yNtr4AKpXowD... #UKCilia2026 /fin

BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series

BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series

eventbrite.co.uk

Great lineup again at the DGZ Focus Workshop tomorrow. Can't wait!

DGZ.bsky.social@dgz.bsky.social · 4mo ago

Join us for the next DGZ Focus Workshop, next week Tuesday, organized by Franziska Lautenschläger & Anne Straube, featuring topics around #cytoskeleton and #molecularmotors. Talks by @lilianpaty.bsky.social , Rhoda Hawkins, Roman Podhajecky & Kanako Iwasaki

The 2026 Otto Warburg Medal winner Maya Schuldiner received the medal from @volkerhaucke-lab.bsky.social after a moving laudatio by Christian Ungermann Thanks to @elsevierconnect.bsky.social for the continuous support!

SAVE THE DATE - our next DGZ International Meeting will take place March 14-17,2027, in Bonn, Germany. Stay tuned!

𝗠𝗲𝗲𝘁 𝗼𝘂𝗿 𝗸𝗲𝘆𝗻𝗼𝘁𝗲 𝘀𝗽𝗲𝗮𝗸𝗲𝗿𝘀 𝗳𝗼𝗿 #𝗖𝗶𝗹𝗶𝗮𝟮𝟬𝟮𝟳! We are grateful for their participation and look forward to welcoming the cilia community on 8-12, March 2027. Wishing you all a happy and inspiring 2026! 🎉 #Cilia #Milan

Another fantastic technology development paper by @davidbreslowlab.bsky.social. Being able to perform microscopy-based CRISPR screens on fixed cells is big. And TZMP1 is a fascinating transition zone proteins. We may be missing many more of these #microproteins. Congrats to all authors!

David Breslow Lab@davidbreslowlab.bsky.social · 9mo ago

Ever wanted to do a genome-scale CRISPR screen for a microscopy phenotype? Pooled CRISPR screens are amazing, but hard to combine with imaging... Excited to share our latest work in Dev Cell on a technology platform for imaging screens and applications to primary cilia: www.cell.com/developmenta...

Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...

An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems - Nature Communications

Proximity labeling allows proteomic mapping of subcellular structures. Here, Sroka et al. develop in situ APEX activation (iAPEX) to overcome limitations of labeling specificity and H2O2 toxicity, app...

nature.com

"... the species of trees we choose to nurture may be just as important as the number of trees we plant." Read the blog post behind the paper by Yao et al. regarding the role of #tree species in the #climate impact of European #forests. communities.springernature.com/posts/rethin...

Rethinking Europe’s Forests: Why Tree Species Matter for Climate Cooling

Yao et al. show that in Europe, forestation’s climate benefits depend on tree species. Converting conifers to broadleaves can reduce summer heat extremes and reverse warming effects of afforestation, ...

communities.springernature.com

Amazing work by the Breslow lab. Super excited to finally see this published. Unbiased CRISPRa screening reveals a novel and unexpected cilia disassembly pathway associated with neurological disease (focal cortical dysplasia). Must read for both #cilia and screening technology enthusiasts.

David Breslow Lab@davidbreslowlab.bsky.social · 9mo ago

Excited to share our latest work on a new cilia disassembly pathway and a link between this pathway and the neurological disorder focal cortical dysplasia: www.science.org/doi/10.1126/... Brief summary: we used a genome-wide CRISPRa GOF screen to identify negative regulators of ciliary signaling...

It was a lot of fun to write this review on cilia proteimics with Bernhard Schermer @cilib.social.cologne.ap.brid.gy and Ronald Ropeman, and we are excited to see it published in the @jcellsci.bsky.social special issue on Cilia and Flagella: from basic Biology to Disease.

Bernhard Schermer@cilib.bsky.social · 9mo ago

📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏 Hope we didn’t miss anything important - apologies if we did! #cilia #ciliopathies #proteomics @theracilproject.bsky.social @for5547.bsky.social tinyurl.com/yc8ztn5v

Interesting connection between primary #cilia and energy #metabolism in #mitochondria. www.biorxiv.org/content/10.1...

Loss of ciliary proteins IFT20 and IFT88 results in defective phagocytosis and metabolism in the RPE

A major proportion of retinal disease-causing genes are related to the primary cilium, a microtubule-based signalling organelle essential for multiple developmental pathways. Previous work has shown t...

biorxiv.org

Very much looking forward to our next focus workshop on #cilia and #centrosomes. We'll have fantastic speakers again.

DGZ.bsky.social@dgz.bsky.social · 10mo ago

The next #DGZ Focus Workshop on #Cilia & #Centrosomes will take place November 25 (end of October is our DGZ meeting in HD). Join us for a great speaker line-up, and big thanks to David Mick @mick-lab.bsky.social & Dagmar Wachten @wachtenlab.bsky.social for organizing!

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend. mpl.mpg.de/news/article... @fau.de 📸 Stephan Spangenberg

New findings in mice cast light on the pathways behind the growth of painful bone tumors in hereditary multiple osteochondroma and suggest that these mechanisms could be targeted to slow the disease’s progression. Learn more in #ScienceSignaling: https://scim.ag/46VRSIp

An ectopic Hedgehog signaling axis drives directional tumor outgrowth in a mouse model of hereditary multiple osteochondromas

Redeployment of a developmental program drives the outgrowth of bone tumors in an inherited disease.

scim.ag

We’re renewing our collaboration with Google DeepMind! We'll keep developing the AlphaFold Database to support protein science worldwide 🎉 To mark the moment we’ve synchronised the database with UniProtKB release 2025_03. www.ebi.ac.uk/about/news/t... 🖥️🧬 #AlphaFold @pdbeurope.bsky.social

Today is the #BBSGlobalDay — an opportunity to raise awareness of this rare condition and offer support to everyone living with BBS and their loved ones 🌍 🌎 🌏 www.img.cas.cz/2025/10/8758...

First pizza lunch after a whirlwind week moving into our brand-new research building. Exhausted, but absolutely thrilled by the incredible facilities & lab space. Can’t wait to dive back into science. A few benches are still waiting for curious minds: PhD students and postdocs, come join us! 😉

'This story shows that it is possible to establish a multibillion-dollar industry purely by letting scientists communicate their research, exchange information and share materials.' www.nature.com/articles/d41...

Monoclonal antibodies revolutionized biomedical science and health care

The story of the discovery of these molecules 50 years ago shows how the free exchange of ideas can lead to life-changing treatments.

nature.com

Science doesn’t need to be pretty and go according to plan; it just needs to lead to a discovery. If doesn’t have to be done alone or together with someone else; there just needs to be a discovery. It doesn’t need to happen fast or slow; just as long as there’s a discovery, then everybody is happy.

Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️ ➡️ www.nature.com/articles/s41... Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Head of the Cell Biology and Biophysics Unit

The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

embl.wd103.myworkdayjobs.com