What in the world am I looking at here? @Nikon? www.nikonsmallworld.com/galleries/20...

Abnormal beating of airway cilia from a child with Primary Ciliary Dyskinesia (PCD) | 2026 Small World in Motion Competition

Ning Xu - Abnormal beating of airway cilia from a child with Primary Ciliary Dyskinesia (PCD), a genetic disorder affecting respiratory function.

nikonsmallworld.com

Millions of beating cilia keep airways clean. At the base of each is the transition zone (TZ), a gate that controls which proteins enter and leave. In our paper out today in Science, we used cryo-FIB-ET to image the TZ inside human airway cells www.science.org/doi/10.1126/...

In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia

The ciliary transition zone (TZ) regulates ciliary proteome composition, yet its molecular architecture, protein content, and contribution to motile ciliopathies remain poorly defined. We applied in situ cryo-electron tomography and subtomogram averaging ...

science.org

Deadline coming up - 22nd Sept

Kat Toropova@kattoropova.bsky.social · 2mo ago

This is a fantastic opportunity, I started my lab through this scheme and the support throughout is phenomenal, please share.

Last call: registration for the 9th Austrian Cryo-EM (ACE) Symposium closes tomorrow, 1 September. 24-25 Sept at the IMP, Vienna BioCenter. Eight invited speakers, selected talks, poster session. events.vbc.ac.at/imp_events/c... #cryoEM #cryoET

Cryo-EM Symposium 2026

Register here for the Cryo-EM Symposium 2026, 24-25 September at the IMP, Campus-Vienna-Biocenter 1, 1030 Vienna.Please select the applicable registration fee and add it to the cart. Please click on t...

events.vbc.ac.at

This is a fantastic opportunity, I started my lab through this scheme and the support throughout is phenomenal, please share.

The Dunn School, Oxford@dunnschool.bsky.social · 2mo ago

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...

Congrats to @clarede-ath.bsky.social and @sujeetkumar.bsky.social (Ruiz lab) on their joint paper. We reveal that YdbL modulates the YdbH-YnbE periplasmic spanning bridge, implicated in lipid transport to the outer membrane. It came out while we were together at GRC journals.asm.org/doi/10.1128/...

Congratulations to the Dunn School postdocs starting new PI positions! Carolin will be joining the University of Birmingham Aakash will be joining the University of Cambridge Rebecca will be joining the St Vincent's Institute of Medical Research (Australia) www.path.ox.ac.uk/news-article...

Dunn School postdocs start new PI positions - Dunn School

Applications are now open to apply for our four year, fully-funded PhD programme in Molecular Cell Biology in Health and Disease.

path.ox.ac.uk

Great opportunity for a fully-funded PhD (UK students) with the brilliant @aakash89.bsky.social at Cambridge Deadline 31st July for Jan 2027 start. Apply here: www.findaphd.com/phds/project...

Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4). www.nature.com/articles/s41...

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 5mo ago

The hidden rules behind mRNA transport. A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs. Read more: mrclmb.ac.uk/news-events/... #LMBNews @cellbiol-mrclmb.bsky.social 🧪

Arsenal are Premier League champions! 🏆

We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

Postdoc position open at the Dunn School, University of Oxford #cryoEM #teamtomo #cilia #postdoc, come join us! Deadline 15th May. www.jobs.ac.uk/job/DRC546/p...

Postdoctoral Research Assistant in Structural Biology at University of Oxford

Looking for a new job opportunity in academia? Check out this job opening for a Postdoctoral Research Assistant in Structural Biology on jobs.ac.uk!

jobs.ac.uk

"The [blue plaque] in the red brick building just behind me celebrates the birth of the age of antibiotics" Prof Chris Tang speaks to the BBC World Service about the world-changing research that took place here in the Dunn School in the 1940s. Listen now: 🎧https://www.bbc.co.uk/programmes/w3ct6sxh

BBC World Service - Discovery, Superbugs: Resistance rising, part 1

Antibiotic resistant bacteria is rising - is a great global crisis on the horizon?

bbc.co.uk

I hadn't seen this before. This is pretty remarkable. Earth and Moon in one NASA photo. ht @astrokatie.com

🥁Calling all Cilia & Centrosome enthusiasts! Registration for the UK Cilia & Centrosome Network Spring meeting in Leeds is open. A homecoming to the place where '9+2' was discovered! Great opportunity for trainees + ECRs to share work + get community feedback. www.eventbrite.co.uk/e/uk-cilia-c...

UK Cilia & Centrosomal Network Meeting Spring Meeting 2026

Join us for the annual in-person meeting of the UK Cilia & Centrosomal Network meeting, which for 2026 will be at the University of Leeds!

eventbrite.co.uk

Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience

Wow! www.nature.com/articles/s41...

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature

Cas9 structures explain topology sensing and off-target activation.

nature.com

New online: A proteome-wide dependency map of protein interaction motifs

A proteome-wide dependency map of protein interaction motifs

Nature Structural & Molecular Biology, Published online: 06 March 2026; doi:10.1038/s41594-026-01762-2Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicted SLiMs required for normal cell proliferation.

dlvr.it

A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...

Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...

Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6... Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

Very proud!

Oxford Biochemistry @oxfordbiochemistry.bsky.social · 10mo ago

Alex Cook @alexandercook.bsky.social in the Matt Higgins @parasitematt.bsky.social lab here @ox.ac.uk has been awarded a Wellcome Career Development Award to start his own laboratory @york.ac.uk . Congratulations Alex! We are delighted for your success but will be sad to see you go. 🏆🎉👏👏👏

Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome! Read the press release here: https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/

very unusual - a tRNA regulated anion channel

cryoEM papers@cryoempapers.bsky.social · 9mo ago

Structural insights into the coordinated regulation of the SLAH family in Arabidopsis thaliana pubmed.ncbi.nlm.nih.gov/41407702/ #cryoEM

Toropova-Roberts lab Christmas lunch 🎄, a joy to work with this lovely bunch!

Many congratulations Teresa! Teresa Thurston was awarded the 2025 Pettenkofer Prize, recognising her contributions to identifying how different bacterial effectors impact the outcome of infection. www.path.ox.ac.uk/news-article...

2025 Pettenkofer Prize awarded to Teresa Thurston - Dunn School

The award by the Pettenkofer Foundation recognised Teresa’s contributions to identifying how different bacterial effectors impact the outcome of infection.

path.ox.ac.uk

A new study by @thurstonlab.bsky.social reveals how a small virulence protein from Salmonella uses molecular mimicry to reprogramme host kinase specificity. Find out more: www.path.ox.ac.uk/news-article...

Converting a kinase through molecular mimicry - Dunn School

Published in EMBO Reports, a new study by the Thurston Group reveals how a small virulence protein from Salmonella called SteE, uses molecular mimicry to reprogramme host kinase specificity.

path.ox.ac.uk

We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22. biochem.weill.cornell.edu/join-our-fac...

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary