Our 3rd #StemGastro conference is just around the corner, and is set to be our biggest series yet. Full of networking, collaboration & the latest research, dont miss out! There's still time to join us this November➡️ bit.ly/4y64skB

Excited to share new work led by outstanding former grad student Kübra Akkaya! We show that Stearoyl-CoA Desaturases (SCDs) regulate intestinal stem and progenitor cell proliferation by balancing fatty acids, sustaining epithelial homeostasis and regeneration.

excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!

bioRxiv Cancer Bio@biorxiv-cancer.bsky.social · 2y ago

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1

Good Sunday, all. What a wonderful collection of papers in #cancermetabolism and #mitochondrialbiology this is! Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social Happy holiday season to you all! "Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski

bart simpson is talking to santa claus who is laying in a chair

ALT: bart simpson is talking to santa claus who is laying in a chair

media.tenor.com

Thrilled to see this paper out!! 🧪 Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors! Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social! rdcu.be/d33uQ 🧵

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...

rdcu.be

Pleased to announce the publication of our new manuscript, "Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging" in Nature Aging today! www.nature.com/articles/s43... Free link: rdcu.be/d1DGk

Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging - Nature Aging

Yeh et al. explore the effects of restricting dietary protein, or isoleucine specifically, in aged mice. They uncover benefits to metabolic health and certain indicators of aging and a sexually dimorp...

nature.com