#fluorescencefriday microglia (yellow) and Abeta plaques (magenta) in our AD mouse model in 3D from a cleared 🧠 using @lifecanvastech.bsky.social SHIELD Courtesy of @shahrzadbahrampour.bsky.social and @nadiahaghbinphd.bsky.social with @mind-western.bsky.social and @neuroak.bsky.social Low-res.

Is it candy? Nope, it is a spooky 👻 cleared mouse 🧠 used for #fluorescencefriday movies

Had a great time at the @mind-western.bsky.social Lightsheet Meeting Series this week, an amazing, interactive talk led by Christopher Pfeiffer-Kelly of LifeCanvas Technologies Inc. @braincanada.bsky.social @maximoprado.bsky.social🔬🖥️🤩

This is what we do!

Marco A. Maximo Prado@maximoprado.bsky.social · 10mo ago

#fluorescencefriday Side by side comparison of alpha synuclein S129 (magenta), a marker of #parkinson’s , in M83 hemyzigous mice injected with human pre formed fibrils @shahrzadbahrampour.bsky.social Vlad Novikov clearing with SHIELD @lifecanvastech.bsky.social imaged at MIND platform @westernu.ca

The things we can do @westernu.ca thanks to platform support grant funding from @braincanada.bsky.social And #NFRF

The MIND Platform @ Western@mind-western.bsky.social · 10mo ago

#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social

#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social

we also thank all talented colleagues @touchscreencog.bsky.social @tridentpct.bsky.social @mind-western.bsky.social @westernubrainscan.bsky.social and support from the #WestonFamilyFoundation #NFRF @braincanada.bsky.social @westernu.ca @schulichmeddent.bsky.social

Marco A. Maximo Prado@maximoprado.bsky.social · 11mo ago

On #worldalzheimersday our team is thrilled with our efforts to understand how amyloid (magenta) interacts with blood vessels (green) and how better 🐁 models and translational approaches will help the fight to #endalz And 🙏 @alzassociation.bsky.social for the support

If you are interested in great #fluorescencefriday videos, images and anything microscopy or MRI related follow our new account for the MIND platform @mind-western.bsky.social @neuroak.bsky.social @touchscreencog.bsky.social @tridentpct.bsky.social

Great news just announced. @neuroak.bsky.social is leading a new funded @braincanada.bsky.social platform that promises to revolutionize the study of neurodegeneration by tackling Patho-connectomics Merging MRI and lightsheet analysis in new models of disease www.schulich.uwo.ca/about/news-e...

Researchers launch brain imaging platform with $2.9M boost from Brain Canada - Schulich School of Medicine & Dentistry - Western University

A new high-resolution imaging platform is revealing the brain in extraordinary detail – and sharing the data with scientists worldwide.

schulich.uwo.ca

#fluorescencefriday blood vessels and amyloid plaques in a 🐭 model of AD. courtesy of @shahrzadbahrampour.bsky.social Luke Smolders and Arash Salahinejad @tridentpct.bsky.social @touchscreencog.bsky.social We will be 🔜 opening up for external services and collaborations via MIND @westernu.ca

late for #fluorescenceFriday. Here are our efforts to look at blood vessels in the 🧠 and of course Abeta plaques @touchscreencog.bsky.social @tridentpct.bsky.social

Our new interest: blood vessels and amyloid plaque interactions after lecanemab treatment of an ApoE4 AD mouse line #fluorescenceFriday @arashsalah.bsky.social and @shahrzadbahrampour.bsky.social for credits

It is #fluorescencefriday and the MIND platform @touchscreencog.bsky.social @tridentpct.bsky.social invites you to see brain blood vessels stained with CD31 and imaged by lightsheet. 🐁 🧠 cleared with SHIELD . thanks as always to @shahrzadbahrampour.bsky.social @arashsalah.bsky.social and company.