Tessera
Folgen

Miro Astore

@miroastore.bsky.social

Postdoc @rockefeller. Making cryoEM into a tool for RNA biophysics one molecule at a time.

37 Posts458 Follower533 Folgt
Miro Astore@miroastore.bsky.social · 3mo ago

Responses to this work have been great. I want to specifically highlight the contributions of Robert Clark tinyurl.com/5dmm5yns. He started this project as an intern and made it into a rigorous study. He's starting to look for postdocs and I cant recommend him highly enough. Please reach out to him!

Have a look at my paper! I have had an amazing time working on this and I'm really proud of the outcome. I want to say thank you in particular to Miro Astore, Sonya Hanson and Pilar Cossio for the...

Have a look at my paper! I have had an amazing time working on this and I'm really proud of the outcome. I want to say thank you in particular to Miro Astore, Sonya Hanson and Pilar Cossio for the int...

tinyurl.com

Rrobbieclark.bsky.social@robbieclark.bsky.social · 3mo ago

Had so much fun with this work! Check it out!

Structural Biology@actacrystd.iucr.org · 7mo ago

Alexandre G. Urzhumtsev: Quantifying distributions of cryo-EM projections #CryoEM #AngularDistributionOfViews #NonUniformDistribution ... #IUCr https://journals.iucr.org/paper?S2059798325011611

Quantifying distributions of cryo-EM projections

We propose a numerical measure to quantify the deviation of a distribution of cryo-EM 2D views from the uniform distribution. This approach allows the traditional two-dimensional projection diagrams to be complemented with quantitative characteristics and simple, easily generated curves that are straightforward to analyze.

journals.iucr.org

Miro Astore@miroastore.bsky.social · 9mo ago

Hello world! It's been a true joy to work on this with Michael. Both him and cryoJAX are things to keep an eye on. They're going to make amazing things happen in cryo and beyond.

Michael O’Brien@m0bri3n.bsky.social · 9mo ago

hey bsky! excited to share what i've been working on for a few years now. cryoJAX: A Cryo-EM Image Simulation Library In JAX www.biorxiv.org/content/10.1... cryoJAX is a modular framework for implementing forward models of cryo-EM image formation. these can be used to build powerful data analyses!

Oli Clarke@olibclarke.bsky.social · 11mo ago

This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 11mo ago

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles https://www.biorxiv.org/content/10.1101/2025.09.08.674935v1

Khaled_Selim Lab@selimlab.bsky.social · last yr.

The results of the first #cryoEM heterogeneity challenge are up on biorxiv! www.biorxiv.org/content/10.1...

The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge

Despite the rise of single particle cryo-electron microscopy (cryo-EM) as a premier method for resolving macromolecular structures at atomic resolution, methods to address molecular heterogeneity in v...

biorxiv.org

Miro Astore@miroastore.bsky.social · last yr.

That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv! biorxiv.org/content/10.110

Lander Lab@landerlab.bsky.social · last yr.

That’s a wrap on the 2025 Cold Spring Harbor CryoEM course! Huge thanks to the amazing students for your enthusiasm, the TAs for your dedication, and the invited lecturers for sharing your expertise. Keep pushing the boundaries of single particle EM - excited to see what you all accomplish next!

Bild