We are delighted to share a new open-access study by Dr Micol Falabella & colleagues, published in @natcomms.nature.com Nature Communications: "COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy" Paper: www.nature.com/articles/s41...

#Training: Our new 2-day Using Conditional Transgenic Models course is designed for anyone using or planning to use conditional models and will equip trainees with a clear understanding of how these models function biologically, as well as the practical ways in which they can fail. Join us in June:

Using Conditional Transgenic Models | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

har.mrc.ac.uk

Catch up on the session "Introduction to Mitochondrial Diseases & Where We Are with Models" delivered by MitoCluster at Queen Square Advances in Mitochondrial Medicine 2026. Link to online recording available via the London Mitochondrial Centre.

London Mitochondrial Centre@londonmito.bsky.social · 3mo ago

Fantastic to have so much of the Mitochondrial Research and Clinical community together at the Queen Square Advances in Mitochondrial Medicine 2026 symposium last week. If you missed it, a recording is available on YouTube. Looking forward to the next meeting! www.youtube.com/watch?v=XbYe...

Excited to share results from the first Business Engagement Fund from the MRC, supporting #academia-#industry collaboration. Work from Nick Greene and Outfox Bio shows LNP-mRNA delivery works effectively in an NKH mouse model—proof of concept for therapeutic mRNA. nmgn.mrc.ukri.org/news/a-busin...

A Business Engagement Fund project to test Lipid Nanoparticle (LNP)-mediated mRNA delivery and efficacy | National Mouse Genetics Network

The Medical Research Council provided £750K in funding for the National Mouse Genetics Network’s Business Engagement Fund with a call for applications in early 2023. The Business Engagement Fund suppo...

nmgn.mrc.ukri.org

Looking forward to seeing you soon at Queen Square Advances in Mitochondrial Medicine 2026! We hope you'll join us for the day, plus the networking reception after (drinks and snacks provided). UCL/UCLH staff & students - contact us via email for your free registration code: bit.ly/QSmitomed2026

Queen Square Advances in Mitochondrial Medicine 2026

The London Mitochondrial Centre is hosting a one-day symposium.

bit.ly

London Mitochondrial Centre@londonmito.bsky.social · 4mo ago

Just over a month to go! Register now to secure your place 👉 bit.ly/QSmitomed2026

Interested in Pre-clinical Mitochondrial Disease Models? MRC MitoCluster is delivering a session this May at Queen Square Advances in Mitochondrial Medicine 2026. Register now to join! #MitochondrialDisease #MitochondrialMedicine #mtDNA #GeneticEngineering #PreclinicalResearch #RareDisease

London Mitochondrial Centre@londonmito.bsky.social · 4mo ago

Just over a month to go! Register now to secure your place 👉 bit.ly/QSmitomed2026

Stealth BioTherapeutics has today announced an award from our Business Engagement Fund to support a new collaboration to evaluate the effects of their compound SBT-589 on biomarkers of disease in a mouse model of Leigh syndrome, a rare mitochondrial disorder: nmgn.mrc.ukri.org/news/busines...

Business Engagement Fund award to support mitochondrial disease research | National Mouse Genetics Network

Stealth BioTherapeutics, a commercial-stage biotechnology company focused on the discovery, development, and commercialisation of novel therapies for diseases involving mitochondrial dysfunction, have...

nmgn.mrc.ukri.org

#mito @mrc-mbu.bsky.social @taylorlabncl.bsky.social @londonmito.bsky.social @mitonewcastle.bsky.social

The Lily Foundation@lilyfoundation.bsky.social · 5mo ago

#RareDiseaseDay is one day each year dedicated to increasing awareness of the 3.5 million people living with a rare disease. Please help to raise awareness and help The Lily Foundation put mito on the map 🗺️ this rare disease day!

Our Best Models Working Group can offer advice on the use of a range of model systems. The next in our series of #MeetTheExpert posts features Laura Greaves, whose group investigates the role of age-related mitochondrial DNA mutations in cancer biology nmgn.mrc.ukri.org/working-grou...

Great two days in York with the MRC National Mouse Genetics Network. Always a pleasure to be invited to share MitoCluster's work, thank you! @mrcmousenetwork.bsky.social @jellevda.bsky.social @lauragreaves.bsky.social @robpitceathly.bsky.social

Our Best Models Working Group can offer advice on the use of a range of model systems. Over the coming weeks, we will be highlighting the diverse expertise of our Working Group, starting with Julia Cordero, an expert in the use of Drosophila to study intestinal biology. #MeetTheExpert

📢 PhD Opportunity with Dr Christopher Carroll at City St George's School of Health & Medical Science, "Advancing genotype-phenotype correlations with Multiplex Assays of Variant Effect". Read more: mrc-lid.lshtm.ac.uk/2026-27-proj... Apply: mrc-lid.lshtm.ac.uk/apply/

✍️ Apply now! Clinical Fellowship in imaging for evaluation of mitochondrial disease severity, progression, and treatment response, in our excellent & supportive team at UCL Queen Square / UCLH NHS Highly Specialised Service for Rare Mitochondrial Disorders shorturl.at/jaSke

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

#Training: Our new Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in February: www.har.mrc.ac.uk/training/cou...

Laboratory Skills for Animal Technicians | Mary Lyon Centre

Having the knowledge and confidence to work safely in the laboratory is a valuable skill for all animal technicians. This course will cover basic theoretical and practical laboratory skills including following COSHH risk assessments, best laboratory practice, use of fume hoods/biosafety cabinets, centrifuges and other laboratory equipment, pipetting skills, using balances and preparing reagents and […]

har.mrc.ac.uk

Our first session of today's #OrganoidsAreUs2025 is dedicated to organoid models in cancer research. We go with ✨ Vincenzo Corbo ✨ Ben Dwyer ✨ Maximilian Reichert ✨ Chiara Braconi Another packed session for a critical and fast-developing field!

Second session on #StemCells #regeneration and #cancer. We start with 🧪 Phil Jones from the @sangerinstitute.bsky.social 🧪 Followed by Suet Yu Leung from Hong Kong Uni and 🧪 Eleanor Earp from @edinburghuni.bsky.social , ✨ First keynote lecture by Helmuth Gehart from @ethz.ch #OrganoidsAreUs2025

Opening session sponsored by @stemcell.com and OLS with a welcome from Director Owen Sansom @cruk-si.bsky.social and Elizabeth Vincan @unimelb.bsky.social . Our plenary speaker Prof Hans Clevers from @utrechtuniversity.bsky.social talks about human epithelial organoids. #OrganoidsAreUs2025

We are ready to go at the CRUK Scotland Institute, @cruk-si.bsky.social, for this exciting meeting, bringing together a huge wealth of new technologies and scientific advances. First session this afternoon. Watch this space! #OrganoidsAreUs2025

It's World Mitochondrial Disease Awareness Week 💚 Since we couldn't #LightUpForMito this year the team's looking lit in green to raise awareness instead! Read more here: www.thelilyfoundation.org.uk/charity/get-... #mitoaware #mitochondrialdisease #worldmitoweek2025 @lilyfoundation.bsky.social

On 14th November, we are once again holding our Network Science Day in York, which is an exciting opportunity for Network members and non-members to engage and develop new collaborations! The meeting is free to attend. Find out more and register by emailing us at Genetics_Network@har.mrc.ac.uk.

Looking for a Clinical Research Fellow to join our team! Please share and apply below by 7th August 👇

Department of Neuromuscular Diseases, UCL QSION@uclqsneuromuscular.bsky.social · last yr.

We are pleased to share an exciting new research opportunity for a clinician with a neurology background to join the London Mitochondrial Team, focusing on innovative MRI techniques in mitochondrial disease: www.ucl.ac.uk/work-at-ucl/...

Join us for Organoids Are Us 2025, a symposium featuring organoids, stem cells, cancer, inflammatory disorders and infectious disease. 📆23 - 26 September 2025 📍Glasgow, Scotland Early bird registration extended to 18th July. Register below! 👇 www.crukscotlandinstitute.ac.uk/events/organ...

Organoids Are Us 2025

Further information about this event including our invited speakers and conference programme are available in the tabs below. If you have any questions, please contact organoids-are-us@crukscotlandinstitute.ac.uk

crukscotlandinstitute.ac.uk

Delighted to share our latest work looking at the role of the RNA-binding proteins Clu1 (yeast)/Clu (flies) in regulating the translation of #mitochondria proteins. Really interesting regulator of mito biology. Huge, long-running effort by PDRA Leonor Miller-Fleming 👏 dx.plos.org/10.1371/jour...

Clu1/Clu form mitochondria-associated granules upon metabolic transitions and regulate mitochondrial protein translation via ribosome interactions

Author summary Mitochondria are essential cellular organelles that perform many important roles in regulating metabolism. They are dynamic in form, function and composition which is crucial to maintai...

dx.plos.org

📢 Exciting 3-year funded PhD opportunity 🧠 Prof Bobby McFarland and Dr Laura Smith are advertising for a PhD student to join their lab at the Newcastle Mitochondrial Research Group. 📅 Closing date: 16th July 2025 ⏰ Start date: 15th September 2025 To apply: www.findaphd.com/phds/project...

PhD studentship - Understanding the causes and identifying treatments for Alpers’ syndrome at Newcastle University on FindAPhD.com

PhD Project - PhD studentship - Understanding the causes and identifying treatments for Alpers’ syndrome at Newcastle University, listed on FindAPhD.com

findaphd.com

10 years ago, The Lily Foundation stood at the heart of the campaign to legalise #mitochondrialdonation. Today, research confirms it’s working, giving families the chance to have healthy, genetically related children 💗 Read more and please share! www.thelilyfoundation.org.uk/news/breakth...

We're proud to announce our work developing a ground-breaking mitochondrial donation IVF treatment has now seen eight healthy babies born 👶 Find out more 👇 www.ncl.ac.uk/press/articl... #WeAreNCL #Health #News #Mitochondria

Eight babies born after Mitochondrial donation

The UK’s pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has seen eight babies born, published research shows.

ncl.ac.uk

We spent a great afternoon at the House of Lords for the launch of the @lifearc.bsky.social Centre for #Rare #Mitochondrial Diseases, supported by @mdukcharity.bsky.social The event centre hosted staff, dignitaries, patients, MPs & those involved in rare disease policy & research. We even unveiled…

Last chance to join us for the Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee @faseborg.bsky.social

FASEB@faseborg.bsky.social · last yr.

Last call for genetics scientists to save $150 at #MDNASRC 2025 with a can't-miss keynote presentation from Thomas Langer from @mpiage.bsky.social ... Save your seat by May 12: buff.ly/A12895w

#Training: Our Mouse Genetics and Colony Management for Animal Technologists course introduces animal technicians and ECRs to the background of mouse genetics, genetic crosses, and calculations of breeding numbers. Book a place on our July course now www.har.mrc.ac.uk/training/cou...

Mouse Genetics and Colony Management for Animal Technologists

This course covers topics such as Mendelian gene inheritance and genetic crosses, as well as important colony management aspects

har.mrc.ac.uk

Fantastic symposium at #BNA2025 @britishneuro.bsky.social highlighting the work the MRC National Mouse Genetics Network and friends! @mrcmousenetwork.bsky.social