🧠🎉 Our new preprint uncovers how a decline in autophagy drives neuronal decay in brain ageing via microtubule cytoskeleton modifications. Thanks to my team @livuni-ismib.bsky.social Funded by BBSRC. #Neuroscience #BrainAgeing #Autophagy #cytoskeleton biorxiv.org/content/10.64898/2026.05.29.728680v1
Natalia Sanchez-Soriano
@natsansor.bsky.social
Drosophilist, Cell biologist, neuroscientist, cytoskeleton, development and ageing University of Liverpool
Now on the GREAT SCIENCE SHARE: Reaching thousands of primary schools across the UK and far beyond talking about the importance of the fruit fly #Drosophila youtu.be/7Q1cOtzMcqk?...
Most important animal - fruit flies
YouTube video by Science & Engineering Education Research & Innovation Hub
youtu.be
I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵
Can anybody tell us, what this all will mean for research at universities? There are two pillars of scientific innovation in our society: industry and universities. Each should be allowed to play at their strengths to have maximal gain. We lose this perspective! www.ukri.org/news/open-le...
Open letter from Ian Chapman to research and innovation community
UKRI Chief Executive outlines changes to UKRI investment approach, addressing concerns about research funding and the financial position of STFC.
ukri.org
Funded 4-year BBSRC NWD PhD to advance neuroscience through vCLEM techniques. 🧠 Are you passionate about EM, neurons, ageing, neurodegeneration? Come and join us! 🙏repost this project with @ianprior.bsky.social @natsansor.bsky.social @aliemliv.bsky.social www.findaphd.com/phds/project...
(BBSRC NWD) Developing a vCLEM pipeline for high-resolution analysis of neurons of the Drosophila brain at University of Liverpool on FindAPhD.com
PhD Project - (BBSRC NWD) Developing a vCLEM pipeline for high-resolution analysis of neurons of the Drosophila brain at University of Liverpool, listed on FindAPhD.com
findaphd.com
More evidence that the UK government (or at least one part of it) is doing everything in its power to destroy the country's scientific base.
The costs of the UK’s Global Talent Visa looks a trifle high in comparison to competitor countries - largely through the Immigration Health Surcharge (which critics say is a form of double taxation as they contribute to the NHS through normal tax on their earnings)
John Gurdon en.wikipedia.org/wiki/John_Gu..., beacon of a generation that tackled head on the deepest question of biology: the development of an organism. The best tribute to him and his peers should be to remember and follow the path they forged for how to do Science in form and content.
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
janelia.org
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research. By @claudia-lopez.bsky.social www.thetransmitter.org/community/ha...
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
thetransmitter.org
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
philanthropy.cam.ac.uk
If you need a simple introduction to axonal cell biology and neurodegeneration for your students, here you go: Shields, Silverdale, Prokop (2024) Understanding the underlying causes of degenerative neural diseases. InnovAiT, 17557380241298477 -- doi.org/10.1177/1755... (OA: tinyurl.com/5dysx3d3)
By popular demand: the Axon Degeneration starter pack. Definitely incomplete so let me know who I missed. go.bsky.app/5BH6mBE
Axon degeneration
Join the conversation
go.bsky.app
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Good news for Kirsty (Biochemistry) and Marisa (MCCM) - Springboard Award winners. Congratulations to both! @livuni-ismib.bsky.social
On #WorldHealthDay, we're celebrating #TeamLivUni biomedical researchers, Dr Kirsty McMillan and Dr Marisa Merino, who have been awarded prestigious Springboard Awards from the Academy of Medical Sciences! 👏💙 🔗 Read more: news.liverpool.ac.uk/2025/04/07/s...
Paper alert! 🚀very happy to have been involved in this collaboration @livuni-ismib.bsky.social where we developed pexophagy reporters for use in Drosophila research. Great work from @drbaronefg.bsky.social royalsocietypublishing.org/doi/10.1098/rs
royalsocietypublishing.org
📢 New Publication! Excited to share my latest research in Open Biology! @royalsocietypublishing.org We developed live Drosophila models to track whole organism and neuronal pexophagy - the selective autophagy of peroxisomes - in vivo. 📄 Full paper: royalsocietypublishing.org/doi/10.1098/... 🧵👇
‘There is a worldwide shortage of scientists and because it’s a worldwide shortage, there’s worldwide competition,' says our Foreign Secretary Professor Alison Noble, as she warns that the UK's visa process and costs could put off scientists from moving to the UK: www.dailymail.co.uk/news/article...
High visa fees putting skilled scientists and entrepreneurs off the UK
Leading scientists have now called on ministers to review the upfront costs that must be paid by workers in science, technology, engineering and maths fields.
dailymail.co.uk
🚀 Hot off the press! Our team findings @livuni-ismib.bsky.social on brain ageing unveil a novel connection between oxidative stress, neuronal microtubules, and the cytoskeletal protein EB1 driving neuronal atrophy. 🎉 A huge thank you to the fantastic team! www.aginganddisease.org/EN/10.14336/...
Oxidative Stress Promotes Axonal Atrophy through Alterations in Microtubules and EB1 Function
<p>Axons are crucial for transmitting neurochemical signals. As organisms age, the ability of neurons to maintain their axons declines; hence, aged axons are more susceptible to damage or dysfunction....
aginganddisease.org
There is still time to apply to this PhD opportunity funded BBSRC NWD PhD. Come join us at @livuni-ismib.bsky.social to study novel roles of Tau and Ribonucleoprotein (RNP) granules in neuronal ageing in Drosophila. Deadline: 31/1/2025. www.findaphd.com/phds/project...
BBSRC NWD: Investigating the nexus between Ribonucleoprotein (RNP) granules and Tau during neuronal ageing at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD: Investigating the nexus between Ribonucleoprotein (RNP) granules and Tau during neuronal ageing at University of Liverpool, listed on FindAPhD.com
findaphd.com
Funded BBSRC NWD PhD to study novel interactions and roles of Tau and Ribonucleoprotein (RNP) granules in neuronal ageing. Join the Sanchez-Soriano and Ashe (@markashe.bsky.social) lab. Interested? Please email for details. Deadline: 31/1/2025. Please share🙂 www.findaphd.com/phds/project...
We are delighted to announce that we have been awarded a Gold #AthenaSwan Award from @advancehe.bsky.social! Thank you to the ISMIB Athena Swan Team who made this all possible! #GenderEquality | #TeamLivUni bit.ly/4jcgcew
It's @biologists.bsky.social Centenary and I am really looking forward to their Biologists@100 meeting in Liverpool. For cell biology folk, the @bscb-official.bsky.social annual meeting is incorporated and there are lots of great speakers. See you there?
This is a serious problem in science (and I would bet other professions, too). The profession cannot afford to lose such a wealth of talent.
“women in the largest discipline (BIO) are 23.26% more likely to leave science after 10 years and 39.74% more likely to leave science at the end of the study period…Our data show that with the passage of time, women disappear from science in ever-larger proportions compared to men” 🧪 #AcademicSky 👩🏽🔬
A brief history of The Company of Biologists - 100 years of supporting scientists!👍👏 journals.biologists.com/jcs/article/...
The Company of Biologists: celebrating 100 years
Summary: As we begin celebrating our 100-year anniversary, we reflect on our extraordinary story so far, consider the Company's current support for our communities and prepare for some inspiring activ...
journals.biologists.com
Okenve-Ramos, P., Gosling, R., Chojnowska-Monga, M., Gupta, K., Shields, S., Alhadyian, H., Collie, C., Gregory, E., Sanchez-Soriano, N. (2024). Neuronal ageing is promoted by the decay of the microtubule cytoskeleton. PLoS Biol, 22(3):e3002504 journals.plos.org/plosbiology/...
Funded BBSRC NWD PhD to study novel interactions and roles of Tau and Ribonucleoprotein (RNP) granules in neuronal ageing. Join the Sanchez-Soriano and Ashe (@markashe.bsky.social) lab. Interested? Please email for details. Deadline: 31/1/2025. Please share🙂 www.findaphd.com/phds/project...
BBSRC NWD: Investigating the nexus between Ribonucleoprotein (RNP) granules and Tau during neuronal ageing at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD: Investigating the nexus between Ribonucleoprotein (RNP) granules and Tau during neuronal ageing at University of Liverpool, listed on FindAPhD.com
findaphd.com
Now official: our next @embl.org course on #Drosophila Genetics & Genomics will be held 3-8 Aug '25. Send in your applications! @bsdb.bsky.social @gensocuk.bsky.social @flybase.bsky.social @fly-eds.bsky.social @socdevbio.bsky.social @the-node.bsky.social @virtualflybrain.bsky.social
Hi Bluesky community! 👋 Are you looking forward to 2025 as much as we are? 👀 We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look! ➡️ s.embl.org/poster-bl #EMBLEvents #molecularbiology #lifesciencetraining
PhD alert!! (MRC DiMeN) in Barsukov and Sanchez-Soriano labs on novel roles of Shank3 with a unique approach: protein structure and cell biology in vivo 🧠 in Drosophila. Deadline Friday 13th December at 5pm (UK time) Interested? www.findaphd.com/phds/project...
Are you aware of our collection of #Drosophila #history articles? Feel free to suggest more!!!!!!!! droso4public.wordpress.com/history/