We invite you to submit your latest research to our upcoming special issue: Proteostasis. This issue will be coordinated by two of our Academic Editors: Pedro Carvalho and Tamotsu Yoshimori. journals.biologists.com/jcs/pages/pr...
Michael Way
@drmichaelway.bsky.social
Cell Biologist working at Crick Institute @crick.ac.uk - Cytoskeleton, Arp2/3 iso-complexes, Signalling and Vaccinia Virus. Editor-in chief Journal Cell Science - @jcellsci.bsky.social - comments are my own opinion
How do poxviruses initiate infection after getting into the cytoplasm? With Tom Calcraft, @miguel-virus-cells.bsky.social & Peter Rosenthal, @crick.ac.uk we solved the structure of the vaccinia virus portal that mediates viral assembly and early mRNA and subsequent genome release. rdcu.be/fwGTn
In situ structure of the poxvirus portal complex
Nature - Cryo-electron tomography uncovers the structure of a conserved hexameric ‘portal complex’ that spans the core wall in vaccinia virus, and shows how it is associated with viral...
rdcu.be
Scientists at the Crick have identified three crucial proteins that make up the ‘portal complex’ in the vaccinia poxvirus. The finding could lead to new ways of treating other poxviruses like mpox which have similar portal complexes. https://bit.ly/45vMhbi
Tuning into the channel helping poxviruses replicate
Uncovering the structure of the poxvirus ‘portal complex’, a channel used by the virus to release its genetic material into infected cells, could help develop new antiviral treatments.
bit.ly
Journal of Cell Science @jcellsci.bsky.social invite you to submit your latest research to their upcoming special issue: Proteostasis. This issue will be coordinated by two JCS Academic Editors: Pedro Carvalho and Tamotsu Yoshimori. Find out more at tinyurl.com/2s3uk7rz
A genuinely nice guy and brilliant scientist who is great to hang out with......we will miss you Jim!
Legendary myosin researcher Jim Sellers retires after many years of making significant contributions to the field and being an unfailingly generous to colleagues - alway sharing materials, insights and wisdom. A symposium honoring Jim will be held in Sept. www.nhlbi.nih.gov/events/2026/...
Pei-Shang Wu, Todd Fallesen and Frank Uhlmann @crick.ac.uk use super-resolution microscopy and semi-automated measurements to dissect chromosome size determinants in fission yeast. journals.biologists.com/jcs/article/... #CellBio #nucleus
Delighted to share our latest preprint "NucleiSky enables cross-scale multimodal registration of microscopy data using nuclei constellations" www.biorxiv.org/content/10.6... Code and App: github.com/CellMigratio...
🔬 Your tax dollars once paid a physicist whose own colleagues told him he was wasting the university's money. In 1951, Charles Townes sat on a D.C. park bench and worked out, on the back of an envelope, how to force molecules to release coherent radiation. 🧵 1/5
In our latest editorial @amjeve.uk & I take on the dreaded impact factor Like Monday mornings no one likes them but you can't ignore them & they keep coming around However there are things we should all do as authors, reviewers & editors journals.biologists.com/dev/article/...
The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
journals.biologists.com
Not to ignore how upsetting and unethical this is, but there is some dark humor in the western blot GIF, or? To me, it pairs well with a jingle like www.youtube.com/watch?v=NNv2...
Circus Theme Song
YouTube video by solo tu radio fm
youtube.com
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)
Is this the future of peer review? New from @biologyopen.bsky.social: expanded Fast & Fair trial paying reviewers £220 per paper The result: rapid peer review with no drop in quality or change in acceptance rate Paying referees makes peer review faster & fairer www.biorxiv.org/content/10.6...
biorxiv.org
Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a totally wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins. forbetterscience.com/2026/06/02/m...
Best shot ever of mobila rays? INSANE FOOTAGE (Aidan Bedford) Annual migration in the sea of Cortez WOW Why do we destroy our oceans and nature everywhere? #WarOnNature #Metacrisis
Most amusing: my name as one of the possible answers on the Portuguese version of “Who wants to be a millionaire?” 😂
Almost at the end of our Japanese adventure - but Mount Fuji decided to put on a show…
New paper out today in @jcellsci.bsky.social on telling statistical from biological significance. I asked Gemini to make a "podcast" summary of it - a bit silly and generic, but not bad. Then again, I'm not much of a podcast person. doi.org/10.1242/jcs.... @lankylaste.bsky.social @crick.ac.uk
One of my role models in academia, combining brilliance with humility-Noboru Mizushima, & I like him even more now ❤️ “If I was given the chance to repeat my research career, I think I would choose to study plant biology.” journals.biologists.com/jcs/article/...
Interview with Noboru Mizushima – President of the Japan Society for Cell Biology
Noboru Mizushima is Professor of Biochemistry and Molecular Biology at the University of Tokyo, Japan, where he runs a laboratory studying the mechanisms and physiological functions of autophagy and o...
journals.biologists.com
Excited to highlight some exciting findings from our recent paper that uncovers how an unusual molecular motor, Myosin F, powers actin dynamics in Toxoplasma gondii. journals.biologists.com/jcs/article/...
Molecular features of myosin F adapted for driving actin flows in Toxoplasma gondii
Highlighted Article: MyoF regulates actin organization in T. gondii by assembling into an oligomeric complex that contains multiple motor domains.
journals.biologists.com
Our most recent paper "Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility" is now out in @jcb.org! Check it out here: rupress.org/jcb/article/...
Wow and no AI involved. The universe is truly stunning.
NASA has unveiled one of the closest images ever captured of Jupiter—and the detail is truly stunning. CREDIT:NASA
Totally deserved!
Sorry for the cliché: not sure how to avoid it... I am very honoured to join such an illustrious list of previous winners And – of course – the credit largely belongs to the fabulous people I have been lucky enough to work with @dunnschool.bsky.social and earlier @mrclmb.ac.uk
Can a single viral protein change how you think 🧠🧐? We think so! Our new preprint shows how herpes simplex virus protein pUL56 turns off neuronal electrical activity. www.biorxiv.org/cgi/content/... 🟦🧵👇
biorxiv.org
How do proteins find their way to the cell's leading edge? @jimgalbraith27.bsky.social & @cathygalbraith.bsky.social break down how bleach line, FLOP, single-particle tracking, FCS & iPALM reveal intracellular fluid flow and an actin-myosin compartment barrier. doi.org/10.1038/s414...
Why is publishing so expensive? In this Editorial, we (@katherine-brown.bsky.social @drmichaelway.bsky.social & @seemagrewal.bsky.social) provide details and context on JCS's finances, and hope to dispel some of the myths around the economics of publishing. journals.biologists.com/jcs/article/...
Crick evolutionary biologist @margaridamcm.bsky.social is working with conservation charity ZSL to investigate an enduring mystery: how the placenta has evolved with incredible variation across species. Read the full story: www.crick.ac.uk/news/2026-03...
SPIN90 modulates the architecture of lamellipodial actin in an ARPC5L dependent fashion. www.biorxiv.org/content/10.6...
biorxiv.org