Boosted by grant, Montreal research seeks to prevent dormant cancer cells from reawakening

Montreal researchers who are studying how ovarian cancer cells can reawaken after going dormant are ultimately trying to prevent cancer from coming back after treatment. The project, led by Dr. Franci...

montreal.citynews.ca

Guidelines for minimal information on cellular senescence experimentation in vivo

This primer introduces the “minimal information on cellular senescence experimentation in vivo” (MICSE) guidelines, which aim to address the challenges in identifying and characterizing senescent cells. It provides an overview of senescence markers in various systems and offers a practical toolset to enhance our understanding of cellular senescence in vivo.

cell.com

Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint - Nature Cell Biology

Hervé, Scelfo et al. show that chromosome mis-segregation induces mTORC2- and ATR-mediated p53 activation through a mechanosensitive checkpoint at the nuclear envelope triggered by altered heterochrom...

doi.org

Immune evasion through mitochondrial transfer in the tumour microenvironment

Nature - Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired...

rdcu.be

Radiothérapie : des mécanismes secrets régulent son efficacité

Les années lumière | Ça fait plus de 70 ans qu’on utilise la radiothérapie pour traiter des tumeurs cancéreuses. Malgré tout, la méthode conserve encore certains mystères. Des scientifiques australien...

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