The MITOtalk of June 2026 takes place this week due to the Euromit meeting next week. And our speaker Heidi McBride will take us to a recently discovered role of mitochondria: peroxisome biogenesis! This thursday (May 28!), usual time and place. See you there?
@nunoraimundo.bsky.social
More organelle conversations! www.sciencedirect.com/science/arti...
Mitochondrial dysfunction triggers a maladaptive peroxisomal response driving lipid accumulation
Mitochondria and peroxisomes communicate to maintain lipid homeostasis, but how the latter adjust to mitochondrial dysfunction remains unclear. Here, …
sciencedirect.com
Looking forward to present at the Organelle Pharmacology conference in Oxford this April! This 2-day event highlights the paradigm shift toward treating diseases by precisely targeting the dysfunction of specific organelles. Registrations still available: my.bps.ac.uk/events/detai...
Event Details
my.bps.ac.uk
March 5th, not february. We sometimes bring the future to the present, but don't travel to the past.
We talk a lot about mitochondrial stress, but how about how do they keep themselves balanced? Good thing our speaker @nieminm.bsky.social knows everything about that, and will tell all on the next MITOtalk. Usual time and place. See you there?
We talk a lot about mitochondrial stress, but how about how do they keep themselves balanced? Good thing our speaker @nieminm.bsky.social knows everything about that, and will tell all on the next MITOtalk. Usual time and place. See you there?
Very cool meeting on "Organelle Pharmacology: A new frontier for drug discovery" taking place this April in Oxford, UK. @britpharmsoc.bsky.social my.bps.ac.uk/events/detai...
Academic seminar reminder! BSRA members, details in your inbox. Non-member and want to attend? See here - bsra.org.uk/events/2026-... We'll have @nunoraimundo.bsky.social from @pennstateuniv.bsky.social on Organelle communication in ageing and age-related diseases. 📅26th Feb ⏲️4pm (GMT) 📍online
Travelling to the future again. This thursday, we will be nosy and learn about mitochondria and their friendships.
Good Sunday, mitolovers. Here is the weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology, with truly remarkable papers: lnkd.in/e7HDuVuU @biomednews.bsky.social #keepreading "Attention is the rarest and purest form of generosity."-Simone Weil
Thinking about remodeling? Mitochondria do that too... and our speaker knows all about it. This thursday, usual time and place. See you there?
5 years of MITOtalks! Feels like it was yesterday when @wanrooij20.bsky.social and @nunoraimundo.bsky.social opened the first MITOtalk to introduce @frezzalab.bsky.social. But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers. Onwards and upwards!
The MITOscience of tomorrow is back. Three short mitochats presented by Débora Santos Rocha @deborasrocha.bsky.social , Valentin L’Hôte @valentinlhote.bsky.social and Marijana Croon @marijanacroon.bsky.social Visit mitotalks.org for zoom link details. Will you time travel with us?
In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation. This thursday, usual time and place. See you there?
Last MitoTALK of 2025! Ewa Warczak @bomba_ewa From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins Thursday, December 4, usual time. See you there? mitotalks.org
New roles for lysosomes... and maybe new targets for Batten disease? Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling | EMBO reports www.embopress.org/doi/full/10....
Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling | EMBO reports
imageimageLoss of Batten disease-associated lysosomal protein CLN3 leads to DNA damage and activation of c-Abl-YAP1-dependent pro-apoptotic signaling which underlies increased apoptosis susceptibility...
embopress.org
The 2025 @embo.org Contact Sites meeting was extraordinary. Congratulations to Michelangelo Campanella and Mélanie Paillard meetings.embo.org/event/25-mem... Marta Giacomello and I are already working to make the 2027 meeting memorable. Keep in touch (like a contact site). It will be 🔥 🔥 🔥
Membrane Contact Sites: Methodology, Biology & Pathology
Intracellular organelles are connected through regions of close apposition known as membrane contact sites (MCS). The growing understanding of MCS’ biology and function has dramatically changed the t…
meetings.embo.org
The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...
(2/2) And from January 2026 onwards: Jan 08 Peter Kim Feb 05 Robin Klemm March 05 Natalie Niemi April 02 Henry Higgs May 07 Eija Pirinen June 04 Heidi McBride usual time and place. See you there?
Now that the summer season is over, it's time for some MITObusiness. (1/2) Oct 02 Kostas Tokatlidis Nov 06 Hiromi Sesaki Dec 04 Ewa Bomba-Warczak
Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
vai.org
MITOtalks and especially MITOchats have been playing with time travel. This week, instead of bringing the future over, we will get there faster: our speaker will tell us all about a mitochondrial progeria syndrome. Usual time and place.
Two mtDNA papers of ours in one PNAS issue: #1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund #2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab www.pnas.org/toc/pnas/122...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
Excited to share our latest paper in Science Advances! We finally dissected a new pathway for mitochondrial quality control upon mtDNA replication stress! Let’s start a short thread! 🧵 www.science.org/doi/10.1126/...
Retromer promotes the lysosomal turnover of mtDNA
Lysosomal uptake of mtDNA controls mitochondrial quality.
science.org
Great chance for Canadian researchers to attend a great scientific meeting in Canada!
Missed the deadline for the abstract submission for the CSMB meeting on Protein Homeostasis – From Basic Science to Human Health? Well the deadline was extended until April 15th! event.fourwaves.com/csmb-prince-...
A reliable and selective AMPK inhibitor - really important tool for AMPK research, congratulations to the team
Pleased to share our new preprint describing mechanistic insights and cellular selectivity of the AMPK inhibitor.
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.