Patrick Forcelli

@paf1984.bsky.social

Neuropharmacologist @ Georgetown University, Prof & Chair, Dept of Pharmacology & Physiology. Preclinical epilepsy researcher & basal ganglia nerd. 🏳️‍🌈

Update 3/16: A very small handful of NIH apportionments have come through — with big exceptions. The ones that OMB has approved are all Congressionally mandated/earmarked. The broad discretionary funds that fund most NIH grants not yet been authorized. (1/2)

Max Kozlov@maxkozlov.bsky.social · 6mo ago

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers. The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇

If it helps, people are mad at Democrats because many of their social media presences produce comms which address what's happening as though we're simply dealing with the consequences of going along with a bad restaurant recommendation. The food isn't just bad, we want to shut down the restaurant.

New paper out from the lab. Tahi Khan, David McFall, and team (1) found increased senescent cells in hippocampus from individuals with temporal lobe epilepsy and in mice after status epilepticus, (2) cleared senescent cells using two strategies & reduced seizures and cognitive impairment in mice.

Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice

Objective The pharmacological treatment of temporal lobe epilepsy (TLE), a disorder characterized by recurrent seizures and cognitive dysfunction, is limited to symptomatic control. Identifying nove...

onlinelibrary.wiley.com

OMG this William G. Young opinion that just dropped (12:30pm) in AAUP v. Rubio. It begins with a postcard sent to Chambers and Young's reply card: "Trump has pardons and tanks, what do you have?" WGY: "We the People of the United States — you and me — have our magnificent Constitution"

Bild

Thank you all the program officers at NIH that persisted through the 2025 fiscal year and were able to fund 99% of the total FY2024 budget. I know this has take a toll on everyone at NIH. Thank you for supporting important health and behavior science and helping to keep the U.S. a leader in science.

Jeremy Berg@jeremymberg.bsky.social · 11mo ago

The fiscal year ends tomorrow. Here are results from NIH Reporter downloaded an hour ago. The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors. 1/3

A graph showing the fraction of annual grant funding committed for NIH for fiscal years 2015 to 2025. The fiscal year 2025 lagged behind but then caught up over the last two months.

I tried something similar using ChatGPT 4.o. "I'm trying to put together a portfolio of three to five papers to highlight my breadth and depth as a research scientist. (I'm Carl Bergstrom.) Could you help me choose papers?" Here's the result.

I'm trying to put together a portfolio of three to five papers to highlight my breadth and depth as a research scientist. (I'm Carl Bergstrom.)

Could you help me choose papers?
ChatGPT said:

Absolutely, Carl. Given your broad body of work across evolutionary biology, information theory, network science, metascience, and science communication, a strong portfolio should showcase both disciplinary depth and interdisciplinary reach. A good starting structure might be:

    Foundational work in evolutionary biology or theoretical ecology

    Papers at the intersection of information theory and biology

    Work in network theory or epidemiological modeling

    Metascience or science reform scholarship

    Public-facing or high-impact commentary on misinformation or science communication

Here’s a possible set of five papers that reflect this breadth and depth:IMPORTANT PAPER BUT DATE IS OFF BY A DECADE

1. "The transmission sense of information" (2002, Biology and Philosophy)

    Why: A conceptual cornerstone in your work on biological information.

    Highlights: Philosophical rigor, interdisciplinary relevance, and enduring influence on how scientists think about information in biological systems.

I'VE NEVER WRITTEN ON THIS SUBJECT OR WITH THESE AUTHORS

2. "Evolutionary dynamics of viral marketing" (2008, PNAS, with K. Lerman and R. Hogg)

    Why: Demonstrates your application of mathematical models to real-world social phenomena.

    Highlights: Network theory, diffusion dynamics, interdisciplinary breadth (social + biological analogies).

I NEVER WROTE THIS OR ANYTHING LIKE IT
3. "The fundamental limitations of contact tracing for COVID-19" (2020, eLife)

    Why: A timely, policy-relevant paper that exemplifies your scientific leadership during the pandemic.

    Highlights: Mathematical epidemiology, real-world application, and high visibility.I NEVER WROTE ABOUT THIS AND NEVER PUBLISHED IN THIS JOURNAL

4. "Systematic inequality and hierarchy in faculty hiring networks" (2015, Science Advances)

    Why: Important contribution to the empirical study of academic hierarchies.

    Highlights: Data-driven metascience, strong methodology, and influence on debates about academic equity.

5. "Misinformation in and about science" (2021, PNAS)

    Why: Captures your role in science communication and misinformation research.

    Highlights: Interdisciplinary scope, impact on public discourse, and relevance in the post-truth era.

The courts *should* put an immediate and unequivocal halt to all use of the CECOT prison in El Salvador, with or without due process. They may not do that. But the *people* of the US still can. Don't lose of sight of this atrocity amidst the other outrages. Make this a key focus of resistance.

John Green did an amazing job with Everything is Tuberculosis. He manages to tell "people stories", inform on the history of medicine, and make a clear argument for public health policy in just over 200 pages. Well worth the read.

John Green@johngreensbluesky.bsky.social · last yr.

Everything Is Tuberculosis will have a SECOND WEEK as a #1 New York Times bestseller. Incredible. (Also, the audiobook is a NYT Bestseller!) I am so, so grateful to everyone who has read and shared that little book.

Not getting much attention, but the Senate GOP is about to start voting - to make sure banks can charge higher overdraft fees. Seriously. Good time to let your Senators know what you think of that.