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PennLINC

@pennlinc.bsky.social

The Lifespan Informatics and Neuroimaging Center at the University of Pennylvannia, headed by @ted-satterthwaite.bsky.social. This account is mostly for announcing new papers, lab members, etc.

23 Posts228 Follower36 Folgt
Steven Meisler@stevenmeisler.com · 4mo ago

Given these scanner differences, harmonization is essential! In unharmonized data, acquisition batch explained up to 70% of microstructural variance. We used cutting-edge longitudinal nonlinear harmonization, which eliminated these effects while preserving developmental effects.

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BIDS (Brain Imaging Data Structure)@bidsstandard.bsky.social · 4mo ago

We are pleased to announce that BIDS Extension Proposal 32 - Microelectrode Electrophysiology is open for community review! github.com/bids-standar... The review period is open from April 20 - May 1. #bids #neuroimaging #electrophysiology

Community Review: BEP032 - Microelectrode Electrophysiology · bids-standard bids-specification · Discussion #2406

We are pleased to announce the community review period for BIDS Extension Proposal (BEP) 032! BEP032 extends the BIDS standard to describe microelectrode electrophysiology data. The draft specifica...

github.com

BIDS (Brain Imaging Data Structure)@bidsstandard.bsky.social · 4mo ago

We are pleased to announce that BIDS Extension Proposal 28 - Provenance is open for community review! github.com/bids-standar... The review period is open from April 20 - May 1. #bids #neuroimaging #provenance

Community Review: BEP028 - Provenance · bids-standard bids-specification · Discussion #2405

We are pleased to announce the community review period for BIDS Extension Proposal (BEP) 028! BEP028 extends the BIDS standard to describe the provenance of BIDS datasets. It introduces new organiz...

github.com

Ted Satterthwaite@ted-satterthwaite.bsky.social · 4mo ago

Huzzah for @stevenmeisler.com, whose preprint on our new fully-processed ABCD dMRI data resource is now out. The super-clear results from this monumental effort will undoubtably change the way we approach studies of white matter development going forward.

Steven Meisler@stevenmeisler.com · 4mo ago

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 www.biorxiv.org/content/10.6...

Neurosynth@neurosynth.bsky.social · 6mo ago

A systematic meta-analysis is hard work—and curation is often the hardest part. Y'all know this better than anyone, and we want to make it easier. What’s one specific piece of information you consistently had to find or extract from every paper? Tell us about it: tally.so/r/QKVbQG #neuroscience

a man is standing in a kitchen with his hands on his chest and asking for help .

Alt: Tom Cruise is standing in a kitchen with his hands on his chest and asking for help, saying "Help me, Help you"

media.tenor.com

Ted Satterthwaite@ted-satterthwaite.bsky.social · 7mo ago

Refreshing this -- we are still reviewing applications for a spring/summer 2026 start date!!!

Ted Satterthwaite@ted-satterthwaite.bsky.social · 8mo ago

#PenNLINC is recruiting a clinical coordinator / lab manager!!! Looking for someone who is good with both people + code, wants to learn to acquire + analyze imaging data. Alumni in this role have written 1st author papers + gone to top grad programs. Website: www.pennlinc.io Job: bit.ly/4ojvCir

Baller Lab@ballerlab.bsky.social · 8mo ago

Excited to share that our new review, "Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis," is out now in Biological Psychiatry! We propose MS as a powerful model for studying how white matter network changes contribute to depression.

Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis

Depression is a common and debilitating psychiatric disorder that is associated with substantial morbidity and mortality. For nearly 40 years, scientists have attempted to localize depression in the b...

biologicalpsychiatryjournal.com

Ted Satterthwaite@ted-satterthwaite.bsky.social · 9mo ago

Truly heroic work by the stellar @cieslakmatt.bsky.social + the HBCD dMRI working group team. Refactored QSIPrep + QSIRecon is the result of nearly 3y of concerted development + testing. It will be a total workhorse for HBCD -- and almost any other dMRI scan. Check it out for your data!!!

Matt Cieslak@cieslakmatt.bsky.social · 9mo ago

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Matt Cieslak@cieslakmatt.bsky.social · 9mo ago

We made numerous updates to the QSIPrep and QSIRecon software packages to better perform on HBCD’s infant/pediatric diffusion MRI. New preprocessing includes partial-Fourier Gibbs unringing, MP-PCA, 2-stage susceptibility distortion correction, SynthStrip/Synthseg and MNIInfant atlases.

A flow diagram describes the preprocessing workflow and additions specifically added for HBCD. Critical additions are Gibbs Unringing, a second stage of distortion correction, MNI Infant support and Synthstrip and Synthseg.
Matt Cieslak@cieslakmatt.bsky.social · 9mo ago

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications

The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...

biorxiv.org

Jonah Padawer-Curry, PhD@jonahpadawercurry.bsky.social · 10mo ago

🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging. 👇🧵 nature.com/articles/s41... #Neuroscience #Psychedelics #BrainImaging

Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function

Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...

nature.com

BIDS (Brain Imaging Data Structure)@bidsstandard.bsky.social · 10mo ago

We are pleased to announce that BIDS Extension Proposal 20 - Eye Tracking is open for community review! github.com/bids-standar... The review period is open from September 29 - October 10. #bids #neuroimaging #eyetracking

Community Review: BEP020 - Eye Tracking · bids-standard bids-specification · Discussion #2218

We are pleased to announce the community review period for BIDS Extension Proposal (BEP) 020! BEP020 extends the BIDS standard to formally specify eye-tracking recordings, which has previously been...

github.com

BIDS (Brain Imaging Data Structure)@bidsstandard.bsky.social · 10mo ago

We are pleased to announce that BIDS Extension Proposal 42 - Electromyogrpahy is open for community review! github.com/bids-standar... The review period is open from September 29 - October 10. #bids #neuroimaging #electromyography #emg

Community Review: BEP042 - Electromyography (EMG) · bids-standard bids-specification · Discussion #2219

We are pleased to announce the community review period for BIDS Extension Proposal (BEP) 042! BEP042 extends the BIDS standard to include electromyography recordings. The draft specification may be...

github.com

Ted Satterthwaite@ted-satterthwaite.bsky.social · last yr.

Check out this stellar work from the one-and-only @valeriejsydnor.bsky.social w/ team at @pennlinc.bsky.social + (many!) friends -- providing new evidence that thalamo-cortical connectivity coordinates the hierarchical progression of cortical plasticity in development. Out in @natneuro.nature.com.

Valerie Jill Sydnor@valeriejsydnor.bsky.social · last yr.

How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...