Got your own (mouse brain-) 3D data from clearing and light sheet imaging, but no idea how to tackle the analysis? We have just the solution for you in Munich: A two-day course on deep learning and VR-assisted segmentation, atlas registration, and so on! Take the course at @erturklab.bsky.social

I entered a contest for a pretty picture! And if you want to help, you can vote for my entry here 😍 awards.helmholtz-imaging.de/site/index.php ("Public Voting" at the top of the site)

Not all brains age the same🧐🧠 Using whole-brain 3D imaging combined with spatial proteomics, @erturklab.bsky.social revealed multiple trajectories of cerebrovascular aging. A fascinating new study: biorxiv.org/content/10.6... I'm always excited to share great work from my colleagues! #Neuroscience

Nature research paper: A deep-learning framework reveals whole-body perturbations at cell level go.nature.com/3Pjox61

A deep-learning framework reveals whole-body perturbations at cell level - Nature

An analysis of diet-induced obesity using MouseMapper—a suite of foundation-model-based deep-learning algorithms—identifies structural alterations of the infraorbital branch of the trigeminal ganglia.

go.nature.com

🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...

happy to share our new protocol paper on wildDISCO for whole-body immunolabeling, tissue clearing & 3D imaging of intact mice at cellular resolution using standard IgG antibodies, for mapping of neuronal, vascular, lymphatic and immune systems across the entire body. www.nature.com/articles/s41...

The Ertürk Lab and me are looking for a motivated and skilled Master's Student (with possible PhD extension)! If you are interested in addiction neurobiology, multimodal brain mapping, proteomics, tissue clearing and 3D imaging, please do not hesitate to apply! tinyurl.com/2esspas6

The Ertürk lab is looking for PhD students. Come work with us in Munich :)

Markus Elsner@markuselsner.bsky.social · 3mo ago

Our lab is looking for a PhD student for a project in cancer biology and neuroimmunology using whole-body imaging, spatial proteomics and (of course) AI. Join us, it will be fun! www.linkedin.com/posts/ali-ma...

Be my colleague! :)

Ali Maximilian Erturk@erturklab.bsky.social · 5mo ago

Hiring in Munich: Staff Scientist / Postdoc in Tissue Clearing and 3D Image Analysis. We’re looking for someone with strong hands-on expertise in tissue clearing, light-sheet microscopy, and quantitative 3D image analysis. Shares and recommendations are very welcome. www.linkedin.com/jobs/view/43...

Oil prices wouldn't be all over the news today if more of our economy was powered by local, secure renewable energy. This isn't an "energy crisis". It's a fossil fuel crisis. 44% of UK electricity came from renewables in 2025. More of that plus an electrified economy => no more oil shocks.

holy shit

❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass

For the record, an earlier version of this post, using Fig 1 from this paper, but without shorts, fell foul of BlueSky's "Adult Content" filter.

PLOS Biology@plosbiology.org · 6mo ago

Why is the human #penis unusually large compared to other primates? @upama.bsky.social @mikejennions.bsky.social &co show that #genital size is a cue for male-male assessment in humans, so #PenisSize likely evolved due to both female choice & male-male rivalry @plosbiology.org 🧪 plos.io/45tjF33

Come work with a great team on one of the big questions at Helmholtz Munich! @helmholtzmunich.bsky.social

Markus Elsner@markuselsner.bsky.social · 6mo ago

We are looking for a PhD student to join our project on developing AI-driven, whole-body multi-omics atlases of mammalian organisms: www.linkedin.com/jobs/view/43...

X/Twitter's rough full volume is around 500 total million posts every day, or 182 (and a half) billion posts per year. By contracts, we found 11.2 million research posts in all of 2025 on there. In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.

Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology

An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.

go.nature.com

Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement. In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.

We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...

💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00. 👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...

Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good

Philip Ruthig@philipruthig.bsky.social · 12mo ago

How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are? In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️ plos.io/4mq5tOy #neuroscience #neuroskyence #whitematter #deeplearning

#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy

How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are? In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️ plos.io/4mq5tOy #neuroscience #neuroskyence #whitematter #deeplearning

Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)

PLOS Biology@plosbiology.org · 12mo ago

#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy

When a microscope facility user asks about how to make a red/green overlay

Our spin-off company is hiring a COO. (Stay tuned for more job offers) www.linkedin.com/jobs/view/42...

bsky.app/profile/matt...

Matthew Parkinson-Bennett@matthewpb.bsky.social · last yr.

“rewrite the entire corpus of human knowledge”

🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer! 💻 Build scalable #bioimaging solutions 🌍 Collaborate globally 🎯 Contribute to open science through #OME #Zarr 📣 Tell your #NGFF friends. Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...

Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...

Karl Deisseroth@deisseroth.bsky.social · 3y ago

The HNC (Human Neural Circuitry) team at our launch celebration at Stanford! Story here: med.stanford.edu/news/all-new...

Signs I am, indeed, living in Munich, pt 1: I just paid 9€ for a pretzel and croissant.

+1000 I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.

Ted Underwood@tedunderwood.com · last yr.

This pattern is going to repeat in one domain after another, and gradually force us to admit that 60% of every job is networking, knowing who to trust, and doing poorly justified risk/benefit assessment.