Tessera
Folgen

Pauline M.L. Coulon

@pmlcoulon.bsky.social

Microbiology, Burkholderia, colony morphotype variation, ECR @AIMI

24 Posts98 Follower99 Folgt
Pauline M.L. Coulon@pmlcoulon.bsky.social · 2mo ago

Excited to be attending #ASMicrobe in Washington, DC! Learn how multi-omics improves understanding of colony morphotype variation in B. pseudomallei and distinguishes true CMV from polyclonal infections. 📍 Poster Board: MECH-FRI-581 Thanks to the Australian ASM ECR International Travel Award.

Pauline M.L. Coulon@pmlcoulon.bsky.social · 7mo ago

I am excited to share that my fourth paper of 2025 is finally out. Perfect timing to conclude the year. journals.asm.org/doi/10.1128/...

Profiling of Burkholderia pseudomallei variants derived from Queensland’s clinical isolates | Microbiology Spectrum

Burkholderia pseudomallei (Bp), the causative agent of melioidosis, is endemic to Australia, Asia, Africa, and the Americas. It predominantly affects Indigenous populations and individuals suffering f...

journals.asm.org

Pauline M.L. Coulon@pmlcoulon.bsky.social · 7mo ago

I am excited to share that my fourth paper of 2025 is finally out. Perfect timing to conclude the year. journals.asm.org/eprint/8YRDZ...

Profiling of Burkholderia pseudomallei variants derived from Queensland’s clinical isolates | Microbiology Spectrum

Burkholderia pseudomallei (Bp), the causative agent of melioidosis, is endemic to Australia, Asia, Africa, and the Americas. It predominantly affects Indigenous populations and individuals suffering f...

journals.asm.org

Pauline M.L. Coulon@pmlcoulon.bsky.social · 8mo ago

Finally out in @PLOSONE! I would like to thank my co-authors and the reviewers for helping us improved the article. journals.plos.org/plosone/arti...

Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland

While investigating colony morphology variation within clinical isolates of Burkholderia pseudomallei (Bp) isolated from a single clinical infection, we identified two distinct strains (based on their...

journals.plos.org

Pauline M.L. Coulon@pmlcoulon.bsky.social · 8mo ago

I have just read Prof E. Peter Greenberg latest editorial paper, explaining why he has been working on P. aeruginosa. That is very refreshing to hear how research is also impacted by interpersonal relationships and personal events. We should hear more about it. doi.org/10.1128/jb.0...

Pseudomonas aeruginosa, my model for research on quorum sensing, biofilms, and opportunistic infections | Journal of Bacteriology

With encouragement from the Journal of Bacteriology Editor in Chief, George O’Toole, I have written this short essay in a style different than Journal of Bacteriology articles on model organisms. It i...

doi.org

Pauline M.L. Coulon@pmlcoulon.bsky.social · 11mo ago

🚨 New preprint out! Proud to share the first reported clinical case of polyclonal #melioidosis infection in QLD—also the first study applying integrative multi-omics at the bacterial level. 🧬 Time to advance diagnosis & build a multi-omics database!

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 11mo ago

Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland https://www.biorxiv.org/content/10.1101/2025.09.09.675021v1

Will Smith@willpjsmith.bsky.social · 11mo ago

Does your lab perform killing assays? TL;DR: we’ve identified a problem that can bias the outcome of killing assays, making antagonism look stronger than it really is. Adding a simple extra step can mitigate this bias!  Out now at #MicrobioJ www.microbiologyresearch.org/content/jour... 1/n

Type VI secretion system activity at lethal antibiotic concentrations leads to overestimation of weapon potency

Competition assays are a mainstay of modern microbiology, offering a simple and cost-effective means to quantify microbe–microbe interactions in vitro. Here, we demonstrate a key weakness of this meth...

microbiologyresearch.org

George O'Toole (he/him/his)@geiselbiofilm.bsky.social · last yr.

A few days ago I had the chance to talk about our work on the gut-lung axis in cystic fibrosis as part of a webinar with The Scientist magazine. You can check it out here (I am the first speaker): www.the-scientist.com/exploring-th...

Exploring the Gut-Lung Axis in Health and Disease

In this webinar, George O’Toole and Jorge Cervantes will discuss how researchers study the communication between the gut and lung in normal and disease states.

the-scientist.com

Victor de Lorenzo (CNB, Madrid)@vdlorenzo.bsky.social · last yr.

The Section of Structural and Synthetic Biology at Imperial College is seeking to support candidates for leading their own laboratory through independent fellowship schemes eg Wellcome Trust, MRC Career Development Award, UKRI Future Leaders Fellowships www.imperial.ac.uk/infectious-d...

Structural and Synthetic Biology

We are interested in understanding molecular mechanisms, especially those that are linked to human disease. We use a multi-disciplinary approach to dissect structures and functions of large macromole...

imperial.ac.uk

Mehrad Hamidian@mehrad-hamidian.bsky.social · last yr.

New paper in Microbial Genomics! Amazing work by @eradah.bsky.social & @liamtobin1.bsky.social & another great collaboration with François Lebreton & Patrick McGann. Here is the link: microbiologyresearch.org/content/jour... #AMR #Acinetobacter @aimi-uts.bsky.social

Phylogenomics, evolution and origin of multidrug-resistant Acinetobacter baumannii ST15

We studied the genomic evolution and transmission dynamics of multidrug-resistant ST15 (Institut Pasteur scheme) Acinetobacter baumannii, examining resistance gene acquisition, clonal diversification,...

microbiologyresearch.org

ASM@asm.org · last yr.

The elimination of federal science and health employees is a direct attack on scientific integrity, expertise and public trust. We stand in support of the career public servants who have dedicated their lives’ work to ensuring U.S. health, safety and security: asm.org/Press-Releas...

ASM Statement on Major Federal Workforce Cuts

ASM stands in support of the career public servants who have dedicated their lives’ work to ensuring health, safety and security in the United States.

asm.org

Scott Delaney@scott-delaney.bsky.social · last yr.

Please please please continue to submit details of your terminated grant using this Google Form 👇 Your submissions continue to be key to understanding patterns of grant terminations and facilitating advocacy and litigation. 💪💪💪

Cancelled NIH grant information submission form

Please use this form to submit information identifying specific NIH grants that have been cancelled for any reason after January 20, 2025. Data from this form will be used to update the Rescinded NIH...

docs.google.com

Pauline M.L. Coulon@pmlcoulon.bsky.social · last yr.

What a great idea! This scheme is already competitive, asking ECRs to have senior researchers’ track records and they want us to secure employment before accessing the scheme while only 2 years postdoc are available if available… What about ECRs going overseas?

ARC Tracker@arc-tracker.bsky.social · last yr.

Here’s a report by John Ross in @timeshighered.bsky.social on ARC Board’s proposal to change grant schemes ▶️ www.timeshighereducation.com/news/arc-gra... [Free login required] Both @scienceau.bsky.social's & I am worried about opportunities & unintended consequences for early-career researchers👇

Excerpt from the article. Black text on white background with a few links in blue text. Excerpt as follows: “Under the ARC board’s proposals, most stand-alone fellowships would be replaced by “embedded fellowships” funded through other grant schemes and capped at two years. “Traditional four-year fellowships concentrate a significant amount of funds on a small number of individual researchers,” a discussion paper explains. Observers fear this could inadvertently deny many ECRs a toehold in academia because current fellowship schemes such as the Discovery Early Career Researcher Award (Decra) and the mid-career Future Fellowships are available to researchers without positions at universities. This could change under the proposals. The discussion paper implies that recipients of embedded fellowships must already be in “the university workforce” – suggesting that ECRs must obtain employment in the sector before gaining eligibility for ARC grants. That is an “unrealistic” expectation, according to Sharath Sriram, president of Science and Technology Australia. “The assumption is all those who apply are already…in academic roles. That might have been true in the 1990s. It’s not the case anymore. “There’s no stability of employment for people until they are six, seven years out of their PhDs. Universities often use success in grants and fellowships to determine who to employ.” A researcher who monitors grant schemes, using the social media handle “ARC Tracker”, was unconvinced that the proposals would improve opportunities for ECRs. They said changes to fellowship schemes needed to avoid closing “pathways” for young researchers and leaving them “overshadowed by the established group leaders”. ARC Board chair Peter Shergold acknowledged the fellowship changes as one of the “stings in the tail” of his proposals, but said a primary goal of his reforms was “contributing to the development of the next generation of researchers”.
Torsten Seemann@torstenseemann.bsky.social · last yr.

🚀🧬 MY former colleague @micamer.bsky.social who I worked with in the early years of my career has released a BLAST service (GUI + API options) which replicates the NCBI services but with faster response times.

@micamer.bsky.social · last yr.

We would love feedback on a new NCBI-BLAST service we are launching today: sky-blast.com Under the hood it's the same BLAST executable and databases provided by NCBI, with a replica of the NIH's interface - providing an alternative to the US gov service that's less congested, faster & more reliable