ProteomicsNews (Ben Orsburn)
@proteomicsnews.bsky.social
Assistant Professor at the University of Pittsburgh. What?? Previous industry CSO. Proteomics researcher with time consuming hobbies in scientific outreach. Opinions are often loud and exclusively my own. www.proteomics.rocks (he/him/his/dude)
Wait. why do I need CoPilot to copy/paste text? Fire up those GPUs in Nebraska, this guy needs to paste unformatted text! Wait. WTF is Auto Rewrite? Is it as stupid as it sounds? What are the Kalshi odds you need to use CoPilot to close a .docx in the next version?
I’m not trying to be political at all. But if people at your work are debating whether you are actually, literally, dead, like totally an unalive corpse being eaten from inside and outside by your own bacterial and fungal flora, maybe you are bad enough at your job that you should be replaced.
Did someone recently describe a cheap labeled protein for a digestion and internal QC? I can't find it anywhere and I could swear I wrote about it somewhere. #proteomics
Missed SCP2026 - here are the published and preprinted highlights - day 1 - proteomicsnews.blogspot.com/2026/07/prep... and day 2 proteomicsnews.blogspot.com/2026/07/prep...
Preprinted data featured in Day 1 at SCP2026!
I've got to start a new page of notes for day 2 or OneNote will definitely crash. Obviously there is a lot of unpublished data here I don'...
proteomicsnews.blogspot.com
#SCP2026 - Luke Khoury with scSeq and SCP on PBMCs - and DRASTICALLY higher data completeness in the latter at 1500-ish proteins. Luke out for this study!
Ginkgo books is adding chatbot interfaces to their automated labs! What could go wrong? rationaloptimistsociety.substack.com/p/the-waymo-...
The Waymo of biotech
The lab that drives itself
rationaloptimistsociety.substack.com
New preprint: Cell-type-resolved spatial proteogenomics, matched genome AND proteome of the same cells. The trick: the flowthrough we normally discard after loading peptides onto an Evotip contains genomic DNA at 85–95% yield. One tip, two molecular layers. www.biorxiv.org/content/10.6...
Cell-type-resolved spatial proteogenomics from matched genome and proteome of the same cells
The genome and proteome of the same cells are rarely measured together, which is especially consequential in cancer, where somatic mutations vary across clones and drive disease. We show that a single...
biorxiv.org
@sufs-paris-rp.bsky.social has an easy to use web portal for submitting comments in response to proposed OMB rule change as well as contacting your representatives: fight2win.standupforscience.net?utm_source=o...
Stand up for Science
Stand up for Science
fight2win.standupforscience.net
Did you write your comment yet on the OMB rules on federally funded science yet? No? Don’t worry, you can do it this weekend. Here are some resources that can help you get started.
We are in the timeline where Taco Bell is leading the response to stop the diarrhea-causing parasite outbreak
Taco Bell Locations Stop Serving Lettuce and Guacamole amid ‘Explosive’ Diarrhea Parasite Outbreak: Report
Some Taco Bell locations in the U.S. are reportedly not serving lettuce, pico de gallo, guacamole and cilantro onion items amid a cyclosporiasis outbreak that’s affected 2,000 people, with Michigan re...
people.com
Tippy tapping-spatial proteomics! proteomicsnews.blogspot.com/2026/07/new-...
New spatial mass spectrometry technology alert - Tippy Tapping-Mode ESI!
Are you interested in getting into spatial mass spectrometry but all the super expensive commercial technologies aren't doing it for you? W...
proteomicsnews.blogspot.com
The LinkedIn algorithm has me dialed in!
Discover new and important motifs in the human proteome with LLMs! It worked for me! proteomicsnews.blogspot.com/2026/07/conv...
Convert protein sequences into text and use language models to reveal all their secrets!
Wow. I'm completely blown away by this one. If you've got VERY GOOD AD BLOCKERS INSTALLED, you can find the popsci article here. Don't cl...
proteomicsnews.blogspot.com
This article is now available in Proteomes: What Are the Practical Applications of Single-Cell Proteomics? @proteomicsnews.bsky.social www.mdpi.com/2227-7382/14... #proteomics #proteomes #proteoforms #MassSpec
Found a fun new preprint on a proteomics web resource, but the portal doesn’t appear to exist - so I emailed the corresponding author …and outlook just informed me that email doesn’t appear to exist. Weird times.
@sciencebob.bsky.social - following because of how sick the suit is that you wore on making impossible items float. Legit impressed.
Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
Heck, the lab might even make things go boom if that's what all you're about
Joshua Sharp@joshuasharp.bsky.social · 2mo agoOne Tomahawk missile = one well-funded research lab working on whatever problem you want for five years.
Ignite Proteomics! Poorly measure 32 proteins for just $2200/sample! Where do you find these knowledgeable investors? I’d love to meet them! www.genomeweb.com/cancer/ignit...
Ignite Proteomics Going Public Via SPAC Deal Valuing the Firm at $150M
The new company, which will list on the New York Stock Exchange, will be named Ignite Proteomics and will be led by Ignite's current management team.
genomeweb.com
The best gif/paper combination I’ve ever lucked into? Possibly! proteomicsnews.blogspot.com/2026/06/scon...
The number of “unified” proteomics algorithms and workflows on preprint servers today
a man says it 's too much while standing in front of a window
ALT: a man says it 's too much while standing in front of a window
media.tenor.com
We preprinted a method of measuring phosphosite stoichimetries (occupancies) in just two mass spectrometry acquisitions, using internal stable isotope labelled controls.
Favorite talk of #ASMS2026 so far has got to be this HIGH SCHOOLER presenting in the drug discovery session!!
Excited to introduce MIRA-MS, a real time artificial intelligence prediction tool for analysis of MHC peptides! If you are at ASMS, check out poster 459 on Thursday. www.biorxiv.org/content/10.6...
biorxiv.org
Stopping Vought’s proposed rule will be critical to save science and future cures. @standupforscience.net created an action center to help you comment and contact Congress. Time to get loud! fight2win.standupforscience.net
Stand up for Science
Stand up for Science
fight2win.standupforscience.net
Calling all Scientists! Research Administrators! Deans! Fans of Science! No one is coming to save us. Here is your assignment. I have written a step by step, easy to understand "how-to" document to help you comment on the proposed OMB rule. elizabethginexi.substack.com/p/what-we-ne...
What We Need to do NEXT: OMB’s Proposed Federal Financial Assistance Rule (OMB 2026-10817)
What OMB’s Proposed Federal Financial Assistance Rule Means in Practice
elizabethginexi.substack.com
