After 10 fantastic years at the @mrc-mbu.bsky.social, @cam.ac.uk, it is time for our lab to move to France!! I am delighted to announce that we will begin a new adventure at the @institutimagine.bsky.social in Paris in September 2026!!
LabPrudent
@prudentlab.bsky.social
Mitochondrial Cell Biology group at @MRC_MBU and @Cambridge_Uni. We study Mitochondrial membrane remodelling, mtDNA dynamics and Membrane Contact Sites. All tweets are from Julien.
Congrats @jellevda.bsky.social and all the team for this exciting study! Thanks for the great and fun collab! 🔥🎉
Visualising heteroplasmic mitochondrial DNA variants in situ? Now out as #mtDNA-smFISH in @cp-devcell.bsky.social! We find purifying selection against pathogenic mtDNA variants through genetic bottlenecks in the germline and the developing brain. www.cell.com/developmenta...
Was indeed pretty fun !
Wonderful and honoured to write a perspective with @prudentlab.bsky.social @mrc-mbu.bsky.social on such an intriguing and cool observation of beautiful mitochondrial biology! Amazing work on how pearling allows mitochondrial genome organisation by @jclandoni.bsky.social @sulianamanley.bsky.social!
Really nice to see this work published!! Huge congrats to @jellevda.bsky.social and all the team!! 🥳👏
Really pleased to see this out @natsmb.nature.com: www.nature.com/articles/s41.... MitoPerturb-Seq combines #singlecell #CRISPR screening with whole-cell Multiome, to identify nuclear modifiers of mtDNA dynamics. @mitocamb.bsky.social @mrc-mbu.bsky.social @prudentlab.bsky.social and Stephen Burr
A bit late to the party, but delighted to share our mini-review on the mitochondrial (mt)DNA life cycle, highlighting emerging mechanisms of mtDNA degradation! Always a pleasure to work with the fantastic @lctabara.bsky.social !!! Have a look 👇 www.nature.com/articles/s41...
Emerging mechanisms of genome degradation during the mtDNA life cycle - Nature Cell Biology
Mitochondrial DNA (mtDNA) is not static but undergoes a regulated ‘life cycle’ that encompasses replication, maintenance, spatial distribution and turnover. Here, we update emerging mtDNA degradative ...
nature.com
Fantastic paper from the McBride lab @mitodynamics.bsky.social ! Congrats Heidi and the whole team!! 🥳🥳
New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org. rdcu.be/eKKz1 🇨🇦
Looking forward for this exciting meeting in Malta!!! Would be fun with lot of exciting Science!!
@prudentlab.bsky.social we are looking forward to your presentation at #IOSCD25 in Malta🌞 Please share with your followers to let them know early bird registration & talk submission close on 01 May! Find out more: bit.ly/IOSCD25_Talk...
@prudentlab.bsky.social we are looking forward to your presentation at #IOSCD25 in Malta🌞 Please share with your followers to let them know early bird registration & talk submission close on 01 May! Find out more: bit.ly/IOSCD25_Talk...