Exciting discovery by @iqbalhamzalab.bsky.social and colleagues! “These findings reveal intercellular heme sharing and identify HRG1 as a potential therapeutic target in hemoglobinopathies.”
Red blood cells don't always make their own heme - under stress, they scavange it from neighbors. Our new paper in @ScienceMagazine reveals a cell-nonautonomous heme acquisition pathway essential for erythroid hemoglobinization. #heme #erythropoiesis #anemia www.science.org/doi/10.1126/...