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Pablo Strobl-Mazzulla

@pstrobl.bsky.social

Developmental Biology. INTECH (Argentina)

43 Posts182 Follower203 Folgt
John Wallingford@jbwallingford.bsky.social · last yr.

Cilia Alert! So excited to finally have this paper on the CPLANE complex out in @natcomms.nature.com! We show that RSG1 is a human ciliopathy protein and links CPLANE to the transition zone. 1/n www.nature.com/articles/s41...

The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture - Nature Communications

The CPLANE complex is essential for ciliogenesis, and mutations to all but one subunit have been associated with ciliopathies. Here they identify three familial mutations in the final subunit, RSG1, t...

nature.com

Pablo Strobl-Mazzulla@pstrobl.bsky.social · last yr.

🧬 New preprint! We’ve identified core microRNAs that orchestrate neural crest delamination and condensation in chick embryos, key for trigeminal ganglion formation. ✨ Introducing cranial MET-miRNAs into trunk neural crest cells reprograms them to gain cranial-like differentiation potential

Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion

Cranial neural crest cells (NCCs) undergo dynamic processes during embryonic development, including delamination from the neural tube by epithelial-to-mesenchymal transition (EMT), migration to the pe...

doi.org

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · last yr.

Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion https://www.biorxiv.org/content/10.1101/2025.06.27.661967v1

Rosa Uribe, PhD@uribelab.bsky.social · last yr.

Check out our work using 3D whole gut spatial genomics, where we found spatially-distinct gene expression patterns along the zebrafish enteric nervous system across 4 to 7 days in development www.biorxiv.org/content/10.1...

Whole-gut spatial genomic analysis reveals molecular regionalization of the differentiating zebrafish enteric nervous system

The enteric nervous system (ENS) is the intrinsic nervous system of the gut and controls essential functions, such as gut motility, intestinal barrier function, and water balance. The ENS displays a c...

biorxiv.org

Rosa Uribe, PhD@uribelab.bsky.social · last yr.

What are the 3D spatial molecular patterns of differentiating enteric nervous system (ENS) in vivo? Are there co-expression networks? Are there spatially variable genes? In our preprint www.biorxiv.org/content/10.1... @RodrigoMoreC et al explored 1/4

Crystal Rogers, PhD@rogerslabucd.bsky.social · last yr.

This paper is now published at @diffjournal.bsky.social! Congratulations to all the hardworking students who made it happen! Shout out to authors 1 & 2! MJ is our “axolotl whisperer” and Raneesh is our computational wizard- both DVM/PhD students @ucdavisvetmed.bsky.social! 💫 doi.org/10.1016/j.di...

NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos

Embryonic exposures to non-steroidal anti-inflammatory drugs (NSAIDs) have been linked to preterm birth, neural tube closure defects, abnormal enteric…

sciencedirect.com

Crystal Rogers, PhD@rogerslabucd.bsky.social · 2y ago

Please check out our recent preprint focused on understanding the cyclooxygenase signaling pathway and effects of pharmacologically inhibiting it in axolotl embryos! This work was spearheaded by MJ Marshall (molecular) and Raneesh Ramarapu (computational) in my lab with help from two undergrads.

Moreno-Mateos Lab@crisprscan.bsky.social · last yr.

First seen in Biorxiv and now published and updated with more data in @naturecomms.bsky.social. With this work we have further enhanced CRISPR-Cas RNA targeting in vivo using transient approaches such as RNP or mRNA-gRNA in zebrafish embryos as vertebrate model. www.nature.com/articles/s41...

Enhanced RNA-targeting CRISPR-Cas technology in zebrafish - Nature Communications

CRISPR-Cas13 RNA-targeting systems comprise an invaluable set of tools in the fields of basic and applied sciences. Here, Moreno-Sánchez, Hernández-Huertas, and Nahón-Cano et al. enhanced the use of t...

nature.com

MetaDocencia@metadocencia.org · last yr.

🔍 ¿Planeas postularte a financiamiento en los próximos dos años? @wellcometrust.bsky.social te invita a observar cómo sus comités evalúan solicitudes de financiamiento. Una oportunidad para comprender mejor el proceso antes de presentar tu propia solicitud. 📅 Convocatoria abierta hasta el 14/4.

Apply to observe a Wellcome funding advisory committee | Prepare to Apply | Wellcome

Find out how to observe a Wellcome funding advisory committee. Researchers who are considering applying for Wellcome funding in the next two years can apply to observe a shortlisting committee.

wellcome.org

Wellcome Trust@wellcometrust.bsky.social · last yr.

Are you a researcher planning to apply for Wellcome funding in the next two years? We’re offering researchers the opportunity to observe a Wellcome funding advisory committee and learn how grant applications are assessed. Learn more ⤵️ wellcome.org/grant-fundin...

Alice Godden@alicegodden.bsky.social · last yr.

Pleased to share my latest pre-print from my PhD work 🚨MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos. 🐸🧬 @biouea.bsky.social #miRNA #Xenopus #neuralcrest #ectoderm #RNA-seq www.biorxiv.org/content/10.1...

MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos.

Neural crest (NC) cells form a multipotent stem cell population specified during neurulation, which undergo an epithelial-to-mesenchymal transition (EMT) and migrate extensively in the developing embr...

biorxiv.org

James Briscoe@jamesbriscoe.bsky.social · last yr.

ICYMI: Commentary on "mechanism" in dev bio Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level journals.biologists.com/dev/article/...

A case for broadening our view of mechanism in developmental biology

ABSTRACT. Developmental biologists can perform studies that describe a phenomenon (descriptive work) and/or explain how the phenomenon works (mechanistic work). There is a prevalent perception that mo...

journals.biologists.com