We're looking for mass spectrometry enthusiasts who thrive on quantitative rigor, innovation and enjoy challenges: - Colleagues eager to propel biological discoveries by inventing the technologies of the future.
Ryan Flynn
@raflynn5.bsky.social
RNA, Glycans, Space, Renewable Energy, and all technologies making lives more interesting. PI at Boston Children’s Hospital SCP Associate Professor at Harvard SCRB
First, the Trump regime wants to impose a time limit on F-1 visas, and now it wants to charge $100k for Optional Practical Training (OPT) for F-1 students. This would affect more than 100k OPT students a year, mostly from India and China.
Exclusive | U.S. Weighs $100,000 Fee for Foreign Students Wanting to Work After Graduation
The proposed policy would particularly affect Silicon Valley, Wall Street and universities.
wsj.com
We already do this and companies who want them are happy to pay for PhD student interns. Why do precious and limited NSF funds need to be deployed for this? Most PhD student pursue industry jobs anyways - that has always been true. Use NSF funds to support basic science that industry wont support!
With academic jobs few and far between, the NSF is testing a new approach to graduate education: Giving Ph.D. students industry experience — and dollars — as part of their training. For more, see my latest for @statnews.com. www.statnews.com/2026/07/29/h...
Cool method for nano pore based peptide sequencing, nice use of copper-free click chemistry as well! www.nature.com/articles/s41...
Sequential reading of a stepwise-shortened peptide immobilized on nanopore - Nature
A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymatic digestion to progressively shorten the N terminus one residue at a time,...
nature.com
“If universities oppose the actions of the administration, they need to say so quickly so that their constituents aren’t left wondering whether there’s a plan. The alternative is a community of university scientists adrift and grasping for a lifeline.” www.science.org/doi/10.1126/...
University science in the US needs a coherent plan
The Trump administration continues to degrade America’s scientific establishment, causing widespread harm to the country’s broader interests and well-being. Last week, the Association of American Univ...
science.org
America's scientific leadership was built on Vannevar Bush's vision that investing in fundamental research creates tomorrow's breakthroughs. Abandoning this vision risks weakening the engine that has driven U.S. prosperity, innovation, and health for generations. 1/
My lab at #Yale has two #riboswitch research openings: 1. Postdoc with mammalian gene manipulation experience (tinyurl.com/zzb269em); 2. Postdoc (or BS, MS) with bioinformatics skills (tinyurl.com/3j73jfcn). Send your cv to me or to Kavita at kumari.thakur@yale.edu.
Postdoctoral Associate in Eukaryotic Cellular Molecular Genetics and RNA Biology — Department of Molecular, Cellular and Developmental Biology (MCDB)
tinyurl.com
Our July Journal club ⬇️🧪 "4D force patterning enables spatial control of angiogenesis" www.pnas.org/doi/10.1073/... #scisky #academicsky
1. The new Trump / Kratsios plan for US science appears explicitly designed to destroy US universities. Diverting money to tech donors is probably just a bonus. Gift link.
Trump’s Plan for Science: More Money for A.I., Less for Universities (Gift Article)
Michael Kratsios, President Trump’s science adviser, proposed overhauling how the government funds research. Democrats said Mr. Trump’s actions had weakened science.
nytimes.com
🎉 36 early-career scientists just joined Pew's biomedical research community, and the challenges they're tackling range from brain aging to memory issues to cancer. Here's what the new Pew scholars and fellows are working on—and why it matters 👇
Congratulations @peterszijj.bsky.social! A new dimension to ADC design that expands the ADC-able proteome 👏
I am happy to share that the main work from my postdoc in the Bertozzi lab is now available on ChemRxiv. chemrxiv.org/doi/abs/10.2... We set out to enhance the internalization of antibody–drug conjugates (ADCs) in a cancer-selective manner.
Yesterday the US Administration supercharged its explicit effort to bar international students from staying in the US after graduation. All Americans should know: 1/3 of *all* STEM PhDs working in the US are immigrants who graduated from US universities, then stayed. www.piie.com/index%2Ephp/...
Trump / Miller are now limiting student visas to 4 years. PhD programs typically run 5-6 years in many disciplines.
Trump administration tightens visa rules for foreign students
Students will need federal permission to stay longer than four years in the US and universities will lose the power to extend visas.
bbc.com
Every single day of this administration, I have thought of my late professor Joe Nye and his work on soft power. Every single day of this administration, Trump finds a new way to hemorrhage soft power from a country that once had more to spare than any in the world.
Isn't it amazing when a fresh new preprint is out on Friday? 😎🥳 Check out the fabulous work by @beatricetropea.bsky.social who gives us a clear mechanistic explanation behind the 'peculiar' structure of the LLO donor preferentially chosen by eukaryotic OST 🤓😍 doi.org/10.64898/202...
New paper! While it has been known that DMS encodes more information than secondary structure, it has never really been characterized. So we did the first large study to look: 7,500 RNAs, all with known 3D structures. We found a lot of cool structural relationships. doi.org/10.1093/nar/...
Thinking on the timescale of days & weeks, progress can feel frustratingly slow. Shifting to the timescale of years, the progress is spectacular: Often faster than expected. The arc of technology development has been awesome. The best is yet to come 🚀 annualreviews.org/content/jour...
🧬 Thrilled to share our latest @biorxiv-microbiol.bsky.social preprint! Here we find that Retron-IX build crazy supramolecular rings scaffolded by DNA molecules that sense phage infection! www.biorxiv.org/content/10.6... Read more below🧵! (1/X)
1/10 🚨Preprint! One RING to rule them all (phages)👑💍⚔️ Bacteria build giant DNA-scaffolded RNase rings (larger than the ribosome!) to shut down viral infection🧬🧵👇 biorxiv.org/content/10.6...
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86 news.mit.edu/2026/mit-pro... #neuroscience
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86
Susumu Tonegawa, a renowned MIT professor of biology and neuroscience and a Nobel laureate, has died at the age of 86. His discovery of how the immune system generates many different antibodies earned...
news.mit.edu
Wow, removing 150 tonnes of CO₂ per year out of thin air! That's a time machine that takes a year to bring us back to an atmosphere we had 0.1 second ago (i.e., less time than it took to read this post).
Ucaneo opens Germany's largest direct air capture plant
Berlin start-up Ucaneo has opened Germany's largest direct air capture plant — 150 tonnes of CO₂ a year, filtered with electricity. Why it matters for Power-to-X.
power-to-x.swiss
We can now steer blood vessels with dynamic forces and even re-direct vessels as they're growing! Great MIT News feature on our new paper in PNAS, outlining how a chance encounter with @ardemp.bskyverified.social helped us identify the role of PIEZO1 in this process: news.mit.edu/2026/mit-eng...
On the neurological basis of cheating/dishonest behavior affected by social normalization and conformity, very a propos to current political climate
Immoral behavior can be contagious. This #fMRI study by Benistant, Dreher &co shows that dishonest contexts lead to learned valuation biases and increased cheating, engaging the lPFC; while the pSTS encodes others’ cheating behavior. 🧪 #AcademicSky #morality plos.io/44jIaPc
@sufs-paris-rp.bsky.social has an easy to use web portal for submitting comments in response to proposed OMB rule change as well as contacting your representatives: fight2win.standupforscience.net?utm_source=o...
Stand up for Science
Stand up for Science
fight2win.standupforscience.net
The story of Grace Science, the Wilsey family who launched this mission to develop gene therapy treatment for NGly deficiency, and the struggles along the way - some inherent to ultrarare disease and some frustratingly imposed by regulatory demands www.statnews.com/2026/07/09/m...
The quest to save Grace — and clear the way for rare disease patients everywhere
How a father’s quest may shape the future of rare disease gene therapy.
statnews.com
Want to direct vessels in a particular direction? No problem, just stretch them! Excited to have been able to help on this super cool work. Among my favorite results are in Figure 5 --> you can make 90 degree junctions by precisely controlling the stretch direction across time.
Out today in PNAS: We show that dynamic "4D" forces can spatially pattern angiogenesis in a PIEZO1-dependent manner. Excitingly, changing force patterns over time enables redirecting sprouting trajectories, forming complex branched geometries: www.pnas.org/doi/10.1073/... #TissueEngineering
New preprint from the group, comparing CRISPRko and CRISPRi via a Perturb-seq readout: www.biorxiv.org/content/10.6...
Direct comparison of CRISPR knockout and interference with Perturb-seq
CRISPR knockout (CRISPRko) and CRISPR interference (CRISPRi) are two workhorse technologies for loss-of-function studies, yet direct comparisons between the two are scant relative to their widespread ...
biorxiv.org
Happy 4th! Just remember what we fought for: the right to choose our own system of weights and measures. youtu.be/JYqfVE-fykk?...
Washington's Dream - SNL
YouTube video by Saturday Night Live
youtu.be
Every morning, this critically endangered Red Ruffed Lemur spreads its arms and sunbathes for up to 40 minutes to warm up instead of burning internal energy. Only 2,500 left in the wild.