Jose Miguel Ramirez

@ramirezjmiguel.bsky.social

PhD in Bioinformatics | Transcriptomics, Genetics, Epigenetics and Data Science

1/ Everything that could go wrong in paper publishing… did. A story of patience, absurdity, and persistence 🌀 <1min From Alfonso Valencia’s lab and a very stubborn PhD student (me).

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🔴Nuevo estudio del BSC y @Universidade do Porto revela que fumar 🚬 imita y acelera el envejecimiento en muchos tejidos del cuerpo humano ⭕Se trata del 1r análisis exhaustivo y multitejido que demuestra que el tabaquismo no sólo perjudica a órganos específicos 📄En Genome Medicine: bsc.es/Zt2

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Do you work in 💫human genetics💫? Have you ever worried about what’s inside your gene annotation GTF⁉️ WELL, YOU SHOULD! 😱 Especially when studying a genetically diverse 🌍 cohort! 🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses! Don't miss this thread🧵⬇️ 1/13

Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation

Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...

biorxiv.org