Our latest preprint, led by PhD student Jacob Cavon, is online: "Multivariate determinants of wearable-measured sleep quality across a large observational cohort: roles of physical activity, gut microbiome, blood analytes, and lifestyle factors." 🦠😴🏃⚕️ www.medrxiv.org/content/10.6... 🧵...

Multivariate determinants of wearable-measured sleep quality across a large observational cohort: roles of physical activity, gut microbiome, blood analytes, and lifestyle factors.

Emerging evidence links the gut microbiome to sleep quality, yet measuring sleep at scale remains challenging. Commercial wearables, such as Fitbit, capture objective sleep and activity data in natura...

medrxiv.org

Our new manuscript, by lead author Gargi Mishra, shows that the IFN-I locus in pDCs is poised for rapid interferon production, as PU.1 and IRF8 establish an open chromatin architecture. #Immunology #Interferons #InnateImmunity #Epigenetics

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells

Plasmacytoid dendritic cells (pDCs) produce robust type I interferons (IFN-I) within hours of viral sensing, while epithelial cells at mucosal surfaces mount a delayed response dominated by type III i...

urldefense.com

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells https://www.biorxiv.org/content/10.64898/2026.06.05.730516v1

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells https://www.biorxiv.org/content/10.64898/2026.06.05.730516v1

Our new manuscript, by lead author Gargi Mishra, shows that the IFN-I locus in pDCs is poised for rapid interferon production, as PU.1 and IRF8 establish an open chromatin architecture. #Immunology #Interferons #InnateImmunity #Epigenetics

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells

Plasmacytoid dendritic cells (pDCs) produce robust type I interferons (IFN-I) within hours of viral sensing, while epithelial cells at mucosal surfaces mount a delayed response dominated by type III i...

urldefense.com

Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.

White-faced Ibis at Nisqually Wildlife Refuge: A treat for bird watchers, as they are rarely spotted there. #wildlife #Ibis #birds #pnw #photography

Hummingbird feeding the chick #birds #hummingbird #mothersday #PNW #Nisqually #photography

Ospreys building a home to start a family. #birds #osprey #pnw #photography

Baby hummingbirds #pnw #birds #hummingbirds #photography #wildlife

📈 Elevate your expertise from foundational to advanced. AAI Summer Immunology Courses offer the ultimate path to mastery. Whether you're refreshing the basics or diving into cutting-edge breakthroughs, our sequential curriculum builds the deep knowledge you need to lead. 🔗 https://ow.ly/tnUn50YLw3O

Join us in Copenhagen, Denmark, for #HCVFlavi2026! The international conference on Hepatitis C Virus, Flaviviruses and Related viruses. 🗓️ Dates: September 14–17, 2026 ⏳Abstracts: May 12, 2026; Early Registration: June 14, 2026 hcv-flavi2026.org #Antivirals #HCV #Flavivirus #Vaccines

Did you know the Santa Cruz Developmental Biology Meeting has an entire session just for NEW PI Talks? And a New PI Keynote Talk? It does! These will be chosen from the abstracts. New PIs, sign up! @socdevbio.bsky.social @rashmi-priya.bsky.social @lowelab.bsky.social scdb2026.sites.ucsc.edu

A male wood duck at lake union. #birds #pnw #seattle #photography #wildlife

Nature! Blue heron getting its dinner. #birds #pnw #ridgefield #photography

J. Michael Bishop, Nobel Prize Winner for Cancer Research, Dies at 90 www.nytimes.com/2026/03/22/o...

J. Michael Bishop, Nobel Prize Winner for Cancer Research, Dies at 90

nytimes.com

Come work with me at Penn State on the dynamics of pathogen elimination. We're hiring up to two positions to support our work on measles/rubella and foot and mouth disease elimination @ciddpsu.bsky.social

Postdoctoral Scholar - Ferrari lab

APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

psu.wd1.myworkdayjobs.com

Sunday is #Stunday! A sunset near Vancouver, Canada from the Trans-Canada Highway. #ColorADay #OrangeSun #photography #ECK #WestCoastKin #PhotographersUnited

Unapologetic leisure, a strong argument that these creatures have the right idea about work life balance. Gloomy Friday in Seattle. #wildlife #photography #PNW guy #CA #priorities

Per @robcrank68.bsky.social, the theme for #BirdOfTheDay is #RuffledFeathers with the alt being #Brown. Here's a wild turkey on the trail in Texas USA this past weekend. #Birds #BirdsSeenIn2026 #WildlifePhotography #Nature #Photography #Texas

A short‑eared owl drifting over the Skagit fields is one of the most extraordinary sights in the Northwest. Every winter these owls return to the Skagit area, turning open farmland into a stage for some of the most graceful hunting flights in nature. #owls #PNW #birds #photography #wildlife #skagit

Short eared owl near Edison, WA. #owls #photography #birds #PNW #wildlife

bioRxiv continues to grow – a brief spike and lag in the pandemic (details of which are included) but a steady increase in submissions since then. % revisions, license choice, etc. all fairly constant. 0.1% withdrawal rate is comparable to journal retraction rates 2/n

As I hauled myself upstairs this morning, I wondered what my ortho would do if he got to try my body on for size for a day. Like would he then believe me when I tell him how much it hurts, even if I don't show it? Based on this I think he'd collapse in a puddle: www.science.org/doi/10.1126/...

Monocyte-derived IL-10 drives sex differences in pain duration

Peripheral monocytes and IL-10 are associated with shorter pain duration in males in both mice and humans.

science.org

Red foxes at Friday Harbor, blending into the island’s fields and forests with their bright coats and curious personalities. Though not native, they’ve settled in over the years. #FridayHarbor #SanJuanIsland #RedFox #WildlifeWatch #PNW #photography

This short‑eared owl is ready for kickoff—eyes sharp, wings steady, and fully locked in. Go Hawks! #SuperOwl #SuperbOwlSunday #gohawks #birds #nfl #football

#GOHAWKS #superbowl #nfl #football #sports #seahawks #seahawksnation #12thman #osprey This osprey has been out here practicing interceptions all morning.

A brief burst of sun in the Skagit Valley and suddenly everything came alive—owl Harrier fights, wings flashing, fields glowing. Sunset hit different tonight. #Skagit #PNW #birds #photography #wildlife

Neil H. Shubin has been elected as the next NAS President! A leading evolutionary biologist and science communicator, Shubin will succeed Marcia McNutt on July 1. The Academy also named Cherry Murray as International Secretary and elected new councilors. Read more: www.nasonline.org/news/2026_pr...