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Rafael Dai Prá

@rdaipra.bsky.social

🇧🇷🇺🇸 PhD in Cellular and Molecular Physiology @yale 26'. Interested in the extreme adaptations of animal physiology. Empowering young brazilian scientists @iniproxima. 📍 New Haven, CT

6 Posts187 Follower351 Folgt
Yale Neuroscience@yaleneuro.bsky.social · last mo.

A new role for the "little brain" of the heart: a team of researchers led by @yaleneuro.bsky.social graduate student Qian Xu & associate professor Rui Chang identified two types of cardiac neurons, essential for heart function and resilience under stress. 🫀🧠

The intrinsic cardiac nervous system is essential for cardiac function and survival

The intrinsic cardiac nervous system (ICNS) is a key node in heart-brain communication and an emerging target for cardiac therapy, yet its physiologic…

sciencedirect.com

Jason Shepherd@jasonsynaptic.bsky.social · 2mo ago

Very excited for our new paper, now out in @cellcellpress.bsky.social! /🧵 The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...

Arc mediates intercellular tau transmission via extracellular vesicles

Tau pathology spreads cell to cell, but the mechanisms of intercellular tau transmission remain unclear. We find that the neuronal gene Arc is critica…

authors.elsevier.com

@canaztekin.bsky.social · 5mo ago

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

science.org

Yale University@yale.edu · 6mo ago

From campus to New Haven streets to the Connecticut shoreline, this storm left behind scenes that feel both stark and beautiful, especially in black and white. Swipe through a few scenes from this week's storm. 📷: Kyle Hurley & Bronwen Pailthorpe

A black and white image depicts a snowy pier leading out to a frozen body of water. Several seagulls are flying overhead. The scene is serene and wintry, with overcast skies.A serene, snowy landscape of an icy body of water with scattered birds on the surface. Faint outlines of distant land and structures are visible under a cloudy sky. A solitary bird is flying, adding dynamic contrast to the stillness.A black and white image of a snowy street lined with trees, branches covered in snow. Four people walk in the distance. Buildings are visible on the left, and the street is tranquil and empty.A black-and-white photo shows a snow-covered street between historical buildings, with a prominent arched bridge connecting them. Bare trees line the street, and a few people walk along the snowy path.
Rafael Dai Prá@rdaipra.bsky.social · 8mo ago

I had the wonderful opportunity to be part of Rising Stars Symposium this year and it was amazing! Great science, great people and a great place!! It was one of my highlights of this year! If you are a neuro grad student, I highly encourage you to apply! ✨

Jim Heys@jim-heys.bsky.social · 9mo ago

Neuro grad students! Applications for the 6th annual - Rising Stars in Neuroscience - due Jan 9! Don’t miss this chance to present research, sharpen science communication skills and connect with peers & faculty. Plus you’ll get to experience stunning Utah! medicine.utah.edu/neurobiology...

Nature Portfolio@natureportfolio.nature.com · 9mo ago

Seahorses have a unique sex role reversal with male pregnancy involving the brood pouch, an evolutionarily novel organ. A study in Nature Ecology & Evolution uses single-cell genomics and in-vivo experiments to reveal the mechanisms of pouch development in seahorses. 🧪

Cellular and molecular mechanisms of seahorse male pregnancy - Nature Ecology & Evolution

Seahorses have a unique sex role reversal with male pregnancy involving the brood pouch, an evolutionarily novel organ. This study uses single-cell genomics and in vivo experiments to reveal the cellular basis and molecular mechanism of pouch development and diversity in seahorses.

go.nature.com

Jan Siemens@jansiemens.bsky.social · 2y ago

My inaugural post on Bluesky - quite fittingly, I'm thrilled to share our first study on heat acclimation, which identifies a neuronal mechanism that drives heat tolerance in mice. (www.nature.com/articles/s41... ) Here is the gist 🧵 (1/n):

Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance - Nature Neuroscience

Ambroziak, Nencini, Pohle and colleagues identify a slowly emerging plasticity mechanism in a discrete set of hypothalamic preoptic neurons that is triggered by long-term heat exposure and that drives...

nature.com