Francisco De La Vega

@ribozyme.bsky.social

Geneticist & Computational Biologist. All opinions are my own.

NEJM editors highlight 3 aspects of recently proposed rule changes as particularly striking: decisions on research funding would be made by political appointees, funding could be cut off midway through a grant period, and foreign interactions would be limited. Learn more: https://nej.md/43yBIUb

A quote on a blue background from The New England Journal of Medicine reads: "A nonscientific, political process for determining what is scientifically sound has not worked in the past and will not work now... Erratic funding would fundamentally undermine innovation and dramatically impair America's ability to address today’s health challenges." It is attributed to "The Editors." The journal's logo is visible at the bottom.

"Defending against emerging diseases is literally a matter of life & death. Our government’s negligence endangers us" I do think RFK Jr & Bhattacharya killing mRNA vaccine R&D, & Bhattacharya killing federal funding for pandemic research & pushing for no preparedness at all, were unforgivable acts

Elizabeth Jacobs, PhD@elizabethjacobs.bsky.social · 3mo ago

I want to share the new OpEd that @jimalwine.bsky.social and I wrote about the dangerous lack of pandemic preparedness in the United States. It doesn’t matter how the outbreak begins. We are not ready, and the only things we can be sure of are death, taxes, and another pandemic.

The FCC is now threatening ABC's broadcast licenses, days after Donald Trump and Melania Trump demanded they fire Jimmy Kimmel. This is straight out of the authoritarian playbook. Mr. President: Read the Constitution. Freedom of speech is the First Amendment for good reason.

Despite the obvious superiority of fresh-frozen material for genomics, many samples are still stored in FFPE and remain challenging to characterize with Whole-genome sequencing. But here comes our solution:

bioRxiv Bioinfo@biorxiv-bioinfo.bsky.social · 5mo ago

An explainable boosting machine model for identifying artifacts caused by formalin-fixed paraffin embedding https://www.biorxiv.org/content/10.64898/2026.03.10.710815v1

"All of these things frighten me, and they should frighten you as well. I made the decision to create a life for myself here, because I viewed this as a place that rewarded determination, hard work, and integrity. It still has a chance to be that place again." open.substack.com/pub/ofthebra...

I’m a Nobel Prize-winning immigrant. I can no longer recognize this country.

Attacks on science and immigrants are destroying America.

open.substack.com

Deadline for abstracts for a chance of a talk at #HiTSeq26 and #ISMB26 is tomorrow- please send your abstracts!

HiTSeq 2026 Conference@hitseq.bsky.social · 4mo ago

Abstract deadline approaching for #HitSeq26 at #ISMB2026: April 9 ⏰🧬💻 If you are developing new algorithms, methods, or tools for high-throughput sequencing data, please submit an abstract for a chance to present a talk or poster at the meeting in Washington, DC, July 12-16.

Delighted to share our latest research from the 23andMe Research Team, just published in @nature.com ! We looked at data from >27,000 participants to uncover how human genetics influences weight loss efficacy and side effects of GLP-1 medications like semaglutide. A short thread 🧵👇

#HitSeq is the annual ISCB gathering focused on high-throughput sequencing algorithms, and about 50% of talks are selected from submitted abstracts. This year’s keynote speakers are Christopher Mason, Mihaela Pertea, and Andre Kahles 🤖

Five Reasons Why It Still Wasn't a Lab Leak Time for some of that civil disagreement that the NIH Director can't get enough of rasmussenretorts.substack.com/p/five-reaso... Dr. A. Rasmussen took the time to put this together, to set the record straight. @angierasmussen.bsky.social Worth reading!

Five Reasons Why It Still Wasn't a Lab Leak

Time for some of that civil disagreement that the NIH Director can't get enough of

rasmussenretorts.substack.com