So happy to be part of this distinguished community! Thank you to all colleagues @embo.org who voted for me!

EMBO@embo.org · last mo.

Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026

Week-end reading? Check out our new review on development and regeneration of glandular epithelia! With two fantastic co-authors: @robinjournot.bsky.social and @candice-merle.bsky.social ! 🤗 authors.elsevier.com/sd/article/S...

Shared molecular and cellular programs during regeneration of glandular epithelia

An emerging concept across multiple adult tissues implies that regeneration involves the transient reactivation of developmental programs, rather than…

authors.elsevier.com

I’m happy to receive this prize, and I thank @gensocuk.bsky.social for the invitation. This achievement belongs to the entire @frelab.bsky.social at @institutcurie.bsky.social Grateful to all team members, collaborators and funding bodies who made it happen!

Genetics Society UK@gensocuk.bsky.social · last mo.

Roger Cox, from the Mouse News Letter Ltd, presents @robinjournot.bsky.social with his Bruce Cattanach Prize for his outstanding PhD thesis related to the use of non-human in vivo animal models!

Glad to receive a PhD prize from the @gensocuk.bsky.social for the work I lead on the origin and diversification of stratified epithelia. Thanks to @frelab.bsky.social , the lab, and all collaborators involved. Special thanks to @candice-merle.bsky.social for her help throughout the project.

Genetics Society UK@gensocuk.bsky.social · 7mo ago

Congratulations to Dr @robinjournot.bsky.social, the winner of our 2026 Bruce Cattanach Prize for his PhD research into the genetic and evolutionary basis of epithelial stratification! genetics.org.uk/medals-and-p...

My time at @institutcurie.bsky.social is done! Over the past months, I completed my PhD, published my first first-author paper in DevCell (www.cell.com/developmenta..., and submitted my first last-author manuscript to bioRxiv (www.biorxiv.org/content/10.1...).

1. Excited to share CONCORD, out in @NatureBiotech, an ML framework for single-cell analysis addressing integration, dimensionality reduction, and denoising in one go by @qinzhu1.🔗 www.nature.com/articles/s41... Check out this CONCORD model of worm development resolving differentiation trajectories:

*New preprint alert* uncovering a mechanical pacemaker that synchronizes nephron formation with branching of the kidney's epithelial tubule tree. Read below to learn about this twisty journey lead by Sam Grindel and Sachin Davis in the lab. [Movie by Nils Lindstrom] www.biorxiv.org/content/10.1...

Check out our beautiful story on tumour clonal dynamics with barcodes, performed in the @frelab.bsky.social by my super talented post-doc @candice-merle.bsky.social and @ivanditerlizzi.bsky.social from @rulands.bsky.social lab! #barcodes #plasticity

bioRxiv Cancer Bio@biorxiv-cancer.bsky.social · 8mo ago

Genetic barcoding of individual cells links cancer evolutionary trajectories and prognostic outcomes https://www.biorxiv.org/content/10.64898/2025.12.01.691488v1

An amazing preprint on molecular evolution (p63-Notch) of Epithelial Multilayering Cross-organ (14 in🐭), Cross-species (7🪰🐟x2🐸🐥🐭👤) single-cell transcriptomics p63+Jag2+ basal signal sendor▶️ p63-Hes1+ suprabasal receivers🐭 bioRxiv 2025 www.biorxiv.org/content/10.1...

🚨 New preprint! We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework. www.biorxiv.org/content/10.1...

The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social www.cell.com/developmenta...

Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila

Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...

cell.com

Our paper is on the cover of @cp-devcell.bsky.social . Image: embryonic murine salivary-gland explants stained for fate determinants; p63 (cyan) and HES1 (yellow). Thanks to everyone involved. doi.org/10.1016/j.de...

🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China

Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq - Nature Genetics

This study introduces single-cell transcription factor (TF) sequencing, a single-cell barcoded and doxycycline-inducible TF overexpression approach that reveals dose-sensitive functional classes of TFs and cellular heterogeneity by mapping TF dose-dependent transcriptomic changes during the reprogramming of mouse embryonic multipotent stromal cells.

nature.com

"Contractile fibroblasts form a transient niche for the branching mammary epithelium." Now out: rdcu.be/eIIKD A great contribution from Jakub Sumbal, showing how stromal cells, and diverse fibroblast subsets, regulate branching morphogenesis. @sumbalovakoledova.bsky.social @frelab.bsky.social

From a FACS-contaminating cell population to a multi-organ project — learn the Behind the Story of our work on conserved signals in epithelial organogenesis 👉 www.sciencedirect.com/science/arti...

Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration

Organ development relies on molecular cues that guide stem cells to differentiate within precise spatial arrangements. After injury, restoring these p…

sciencedirect.com

the Node@the-node.bsky.social · 11mo ago

Geometry first: how positional cues dictate fate in bilayered epithelia Read @robinjournot.bsky.social's behind the paper story featuring the Hippo/YAP and Notch signalling pathways. thenode.biologists.com/geometry-fir...

Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included. training.institut-curie.org/courses/deve...

🧵Just out ! We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration. Here’s the story👇 authors.elsevier.com/c/1lM285Sx5g... Work done in @frelab.bsky.social at ‪ ‪ @institutcurie.bsky.social

Notch1 activation in basal cells triggers a progressive basal-to-luminal cell-fate switch in the mouse mammary gland but also in adult cells of the lacrimal, salivary and prostatic glands Silvia Fre and coworkers @frelab.bsky.social @institutcurie.bsky.social www.embopress.org/doi/full/10....

I am very excited to share our most recent work on how ‘Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration’ ☺️ Thanks a lot to @silviabarbiero.bsky.social @davidbrueckner.bsky.social @priscaliberali.bsky.social @ehannezo.bsky.social and all the co-authors!

Prisca Liberali@priscaliberali.bsky.social · 2y ago

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...

@thejohnnyyu.bsky.social, @therealnima.bsky.social , Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t

A new platform, a new post! Our #Stemcell #DevBio and #Regeneration story by Silvia Fre's lab at InstitutCurie is on biorXiv. Link: tinyurl.com/2uspcd3u We reveal how 4 epithelia self-organize during embryonic development and regeneration.