A big — if preliminary — win for #AAP and pro- #vaccine policy today. A court has ruled Robert Kennedy's reconstitution of #ACIP and his department's rewriting of the childhood vaccination schedule are likely illegal. Developing story. www.statnews.com/2026/03/16/k...

Federal judge stalls health secretary RFK Jr.’s overhaul of vaccine policy

Breaking: A federal judge on Monday stalled major parts of health secretary Robert F. Kennedy Jr.’s campaign to remake vaccine policy in the U.S.

statnews.com

Amidst the discussion of measles reestablishment in the US, the risk of rubella provides an instructive example of long-term delayed consequences that could resonate for decades ... or be stopped by coming to our senses 1/

An ‘off-the-shelf’ neoantigen #vaccine shows safety and immunogenicity in people with #Lynchsyndrome, advancing hopes for preventive cancer vaccines. News & Views from Zsofia Stadler, Yonina Murciano-Goroff @ Memorial Sloan Kettering Cancer Center https://www.nature.com/articles/s41591-026-04248-2

Preventive vaccines for hereditary cancer syndromes - Nature Medicine

An ‘off-the-shelf’ neoantigen vaccine shows safety and immunogenicity in individuals with Lynch syndrome, further advancing hopes for preventive vaccines for hereditary cancer syndromes.

nature.com

A doozy of a quote in this profile of the "godfather of vaccines" by @helenbranswell.bsky.social, as he watches his field trend in the wrong direction “All I can say is that I’m beginning to regret having lived so long — because we’re going downhill,” www.statnews.com/2026/03/02/s...

A titan of vaccine development sees his field’s achievements slip away

Stanley Plotkin, the 93-year-old "godfather of vaccines," is watching his field’s achievements slip away.

statnews.com

State vaccine requirements for school entry are absolutely essential if we have any hope of maintaining herd immunity. It is madness for states to repeal these requirements. And vaccine exemptions should not be permitted unless for a documented medical contraindication.

The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system www.nature.com/articles/s41...

First evidence that healthy donor fecal microbiota transplant, added to immunotherapy, can enhance efficacy vs cancer 3 clinical trial reports (renal, small cell lung, melanoma) nature.com/articles/s41... nature.com/articles/s41... nature.com/articles/s41... Holy 💩!

Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial - Nature Medicine

In a phase 2 trial evaluating healthy donor fecal microbial transplantation plus either anti-PD-1 in patients with non-small cell lung cancer or anti-PD-1 and anti-CTLA-4 in patients with melanoma, en...

nature.com

Tomorrow’s front page of the Minnesota Star Tribune: Jan. 23, 2026

Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers. Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social

US science after a year of Trump: what has been lost and what remains

A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.

nature.com

A vaccine to prevent colon cancer. Proof-of-concept for strong immune response and safety via neoantigens given to people carrying mutations for Lynch syndrome nature.com/articles/s41...

Nous-209 neoantigen vaccine for cancer prevention in Lynch syndrome carriers: a phase 1b/2 trial - Nature Medicine

In a phase 1b/2 trial, an off-the-shelf vaccine using gorilla adenoviral and modified vaccinia Ankara vectors with over 200 mutated peptides known to be present in persons with mismatch-repair-deficie...

nature.com

This study should never have been greenlit but glad it's been cancelled. @boghuma.bsky.social and The Guardian article below nicely summarize the key issues. Leaked protocol with more discussion of all the problems with this trial: insidemedicine.substack.com/p/scoop-the-...

BK. Titanji@boghuma.bsky.social · 8mo ago

One of the most valuable lessons my father taught me was to use my voice to speak up whenever I see wrong doing. Thanks to every researcher who spoke up against this unethical study and for every reporter who amplified. Advocacy matters. @melodyschreiber.com www.theguardian.com/us-news/2026...

My kitchen table issue is “don’t shoot people at their kitchen tables”

Did slashing multiple vaccines from the childhood vaccine schedule bring the US in line with other countries? In a word, no. The US now recommends all kids be protected against fewer diseases than South Korea, Israel, Saudi Arabia, Taiwan & many more. www.statnews.com/2026/01/09/c...

When it comes to vaccine schedules, the U.S. is now the outlier

A STAT analysis of vaccine recommendations in 38 countries suggests the U.S. is now an outlier.

statnews.com

We saw Jan 6, 2021 and Jan 7, 2026 with our own eyes. This is not Orwell's 1984.

The planned hepatitis B birth-dose trial in Guinea-Bissau raises serious ethical concerns. Withholding a proven, life-saving vaccine from newborns to answer speculative questions is an absence of equipoise with real downstream harms for trust in vaccines. bktitanji.substack.com/p/how-unethi...

How Unethical Research Seeds Medical Mistrust

The absence of equipoise can turn research into harm

bktitanji.substack.com

💯The mainstream media's coverage has contributed to how we got to this point.

Gregg Gonsalves@gregggonsalves.bsky.social · 9mo ago

I am begging reporters to heed @jessicacalarco.com's warning here. There is too much equivocation even in articles that highlight RFK Jr's anti-vaccine zealotry. These articles juxtapose a claim he offers, with "other experts say." It is a pernicious tic of mainstream journalism and has to stop.

Three studies that leverage blood-based gene expression data identify host response signatures in #sepsis and critical illnesses, opening a pathway to mechanism-anchored #precisiontherapy. News & Views from Robert Stevens and Carl Harris @jhu.edu https://www.nature.com/articles/s41591-025-04005-x

Unlocking host response signatures in sepsis and critical illnesses - Nature Medicine

Three studies that leverage blood-based gene expression data identify molecular and cellular host response signatures in sepsis and critical illnesses, opening a pathway to mechanism-anchored precision therapy.

nature.com

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

📰 Please read this important news feature in @natmed.nature.com written by @marianneguenot.bsky.social It is impossible to reconcile this administration's alleged commitment to "Gold Standard Science" with their harmful actions against important biomedical research www.nature.com/articles/s41...

The damage done - Nature Medicine

When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.

nature.com

Ever since I learned about this study enrolling I have been eagerly awaiting the results. Researchers in Uganda took a centuries-old cultural practice mothers carrying babies on their backs in cloth wraps and turned it into a public health tool. You got to love it! www.nejm.org/doi/full/10....

Permethrin-Treated Baby Wraps for the Prevention of Malaria | NEJM

Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged the traditional practice of mothers carrying children on their backs in cloth wraps to assess whether treating t...

nejm.org

SO the people actively sowing distrust in vaccines (i.e. many of the people in RFK's new ACIP) are also saying that we need to change safe and highly effective vaccine schedules because of this same lack of trust. Make it make sense!

Atul Gawande@agawande.bsky.social · 12mo ago

Finally, an answer came back: we must make changes because trust in vaccines has decreased. “The signal that is prompting this is not one of safety, but one of trust,” said member Robert Malone. 3/

ACIP voted 7-3 to NOT recommend MMRV combo vaccine for kids <4yo. Then in a confusing second vote (1 yes, 8 no, 3 abstentions - some citing confusion), they kept VFC coverage for the same vaccine they just said not to use. This chaos matters for every family. 1/8

Here's the upshot on hepatitis B vaccination at birth: - it's extremely safe - the earlier it's given, the better it protects against transmission from mother-to-child - screening fails to capture many cases and is not done at all in many cases - perinatal HBV infection is catastrophic

A horrible horrible decision with NO rationale.

Alex Wayne@aawayne.bsky.social · 12mo ago

NEWS: By vaccinating babies at birth, the U.S. nearly eradicated hepatitis-B in children. Kennedy's vaccine advisory panel is expected this week to recommend delaying the shot, opening a window for kids to be infected. Exclusive by @jackie-fortier.bsky.social kffhealthnews.org/news/article...

On the Trump administration's cruel disbanding of the Pediatric Brain Tumor Consortium: my op-ed @statnews.com My 12-year-old son died from brain cancer. This research would have helped children like him www.statnews.com/2025/09/15/p...

The Trump admin’s cruel disbanding of the Pediatric Brain Tumor Consortium

My 12-year-old son died from brain cancer. The defunding of the Pediatric Brain Tumor Consortium will deny treatments to children like him.

statnews.com

Do NOT allow them to rewrite history with disinformation. #COVID vaccines worked remarkably well and allowed us to come out of a global pandemic. A picture is worth a thousand words.

🌟Proud to publish these exciting data in #NatureMedicine -- final results from a phase 1/2 trial + a case series show strong efficacy of GD2 CAR-T cells in children with high risk #Neuroblastoma #immunotherapy #OncSky #PedSky @natureportfolio.nature.com www.nature.com/articles/s41...

GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/phase 2 trial - Nature Medicine

In the final analysis of a phase 1/phase 2 trial of autologous GD2-targeting CAR T cells in pediatric patients with high-risk metastatic, relapsed or refractory neuroblastoma, treatment was overall we...

nature.com

AAP's immunization recommendations are based only in the science, the needs of children, and the care that pediatricians have for the children in every community. If you have any questions about our recommended schedule, reach out to your pediatrician. aao.org

New and important #NatureMedicine correspondence on the health consequences of forced displacement in Gaza "These proposals are not humanitarian...Every effort must center on the health, humanity and rights of Palestinians, not their removal." www.nature.com/articles/d41...

🌟NEW in #NatureMedicine: Results from a phase 2 trial suggest that anti-PD-1 #immunotherapy should be the preferred treatment choice for patients with unresectable desmoplastic #melanoma -- complete response rate of 37% and a post hoc ORR of 89% (!!) #OncSky #MedSky www.nature.com/articles/s41...

Anti-PD-1 therapy in unresectable desmoplastic melanoma: the phase 2 SWOG S1512 trial - Nature Medicine

In cohort B of the phase 2 SWOG S1512 trial, pembrolizumab monotherapy in patients with unresectable desmoplastic melanoma elicited a complete response rate of 37% and an objective response rate of 89...

nature.com