Our 💻x🧫 collaboration @saravasconcelos.bsky.social @uhnresearch.ca with ATOMS lab @utoronto.ca is out on @pnasnexus.org. We showed the correlation ⛓️ between the local variability of interstitial flow🚰 and the dimensional variability of microvessel 🪢 across different size scale in vitro. Enjoy 📖!
In the quest to engineer large tissues for transplants, preserving flow conditions during vasculature scale-up can be tricky. A computational–experimental framework can help predict interstitial flow, allowing effective pre-vascularization. In PNAS Nexus: https://ow.ly/sja050ZzWfq