Zaven Sargsyan
@sargsyanz.bsky.social
Internist at Baylor College of Medicine, Houston
~ 1895 Heidelberg, Germany ~ Scientist: Yo Herr Nissl what should we call the microscopic anatomy you discovered. German neuropathologist Franz Nissl (wearing the head mirror upside down): uh call it fucking a- Nissl’s fucking uhhhhh…. UHHhHh- Substance
Last week was full of lies and misinformation. Let’s start this week with data. open.substack.com/pub/insideme...
One graph to shut RFK Jr. up.
The best argument against his nonsense is data. Here it is...
open.substack.com
Astonishing. RFK Jr. adds 8 members to a 6 member FDA advisory panel. 6 of them were sellers of peptides, and the 7th a compounding pharmacist. In an 8-6 vote with all 8 votes coming from these new panel members, the panel approved 4 peptides against the objections of FDA scientists.
FDA Panel Supports Lifting Restrictions on Four Peptides (Gift Article)
In an all-day hearing, the agency’s scientists argued against allowing broad access to unproven drugs that the agency had banned three years ago.
nytimes.com
This was a great study evidence.nejm.org/doi/full/10....
A Randomized Trial of Interval Likelihood Ratios for Clinical Decision-Making
Dichotomized reporting of diagnostic test results may oversimplify test characteristics. Interval likelihood ratios (ILRs), test characteristics across a range of values, offer a nuanced alternativ...
evidence.nejm.org
"We describe the case of a 42-year-old woman who self-treated undiagnosed Addison's disease for several years with soy sauce and liquorice sticks. [...] Our patient described an unusual diet of liquorice sticks and soy sauce, consuming around 46 g of salt per week."
Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease - PubMed
Addison's disease is a relatively common disorder to endocrinologists, but is rare and potentially fatal when presenting acutely. Treatment now involves replacement of glucocorticoids and mineralocort...
pubmed.ncbi.nlm.nih.gov
Reading some one star user reviews for the Draft Kings app:
A 47-year-old man with heart failure with a reduced ejection fraction and an ICD for the primary prevention of sudden cardiac death presented with an unheralded syncopal event, which had been captured by video surveillance at work. Read the full case details: https://nej.md/4w1yfJM
Dear all companies, Sending me a satisfaction survey after you sell me a service or goods is a great way to make me suddenly dissatisfied. Thanks, Most customers
So much we need to learn about tick-related infections, so this effort by HHS is welcome. But I worry deeply about the company they keep in their announcement. More here: #IDSky #Medsky voices.nejm.org/doi/full/10....
Lyme Disease Deserves Better — But Better Starts with Better Evidence
A recent federal announcement to combat tick-borne disease has a promising premise but deserves scrutiny.
voices.nejm.org
accidentally put two diagnoses of exclusion on my differential and now i don’t know what to do
YOU’RE LISTENING TO SISYPHUS FM, THE HOME OF NON-STOP ROCK
too many stupid people have money; that's why I'm launching protein cigarettes
Making a case for bedside rounds on day one of service
I genuinely think the best way to deal with this shit is to run nonstop psa's showing cows being milked and how much shit is involved. actual shit
CNN@cnn.com · 4mo agoBackers of raw milk are pushing to make the potentially dangerous product more widely available and easier to obtain, even as a new outbreak — one of at least five in the past year — sickens US children.
People seem pretty upset about this #onhere but as someone who works in this hood and bikes most days, this is more functional as a bike lock than the median commenter seems to think. Also I get a dad-joke chuckle out of it as a bicyclic bicycle lock (a bicycle to which you can lock your bicycle 🥁)
Only In Boston@onlyinbos.bsky.social · 4mo agoKendall Square has a bike rack shaped like a caffeine molecule. ☕🐸
hobby: pasting text into the URL bar and then copying it again to launder it of weird formatting
jumping onto a tram and frantically telling the driver to follow that other tram
Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
I did some research to try and figure out when my death date would be if there had been no treatment for my cancer. I don't know why I assumed it would be some date in the future, but, in fact, I passed the middle of the "no treatment survival" bell curve more than a year ago. Thanks chemo.
