Journal club article by @tomikostevc.bsky.social & @sawitzkilab.bsky.social discussing a recent #preprint from @sciencekyle.bsky.social that uses a synthetic cytokine receptor to simultaneously induce inflammatory and phagocytic phenotypes in a macrophage rdcu.be/ftTPx

Excited to share a highlight that Birgit Sawitzki and I wrote about a recent preprint on fine-tuning macrophage polarization using synthetic cytokine receptors from the @sciencekyle.bsky.social Lab! @preprintclub.bsky.social

Happy to pitch our findings and ideas at the Bioengineering Symposium by @mdc-berlin.bsky.social today

From 25 to 27 June 2026, the 15th Translational Immunology School (TIS) of the #DGfI brought together early-career researchers and leading international experts in Potsdam. 😊 dgfi.org/akademie-fue... Chair: B. Grimbacher, Co-Chair: @sawitzkilab.bsky.social @efis-immunology.bsky.social #immunology

Inspiring exchange of ideas and experiences with the next generation of translational immunologists at the Translational Immunology School by @dgfi-org.bsky.social 💡

Great meeting the ME/CFS community last week in Berlin and sharing our latest findings!

ME/CFS Research Foundation@mecfsresearch.bsky.social · 3mo ago

Zwei Tage #MECFSConf2026 sind vorbei. Danke an alle Speakers, an alle, die dabei waren — im Saal, im Stream, in den Betten — und an alle, die zum Gelingen beigetragen haben! Aufzeichnungen folgen bald. #MECFSConf2026 #MECFS #LongCovid #PostCovid

Inspiring week at Utrecht University for our team! Our PhD Adrian joined fellow TopGut DCs, and our PI Birgit Sawitzki was there too. A great mix of science, collaboration & new ideas - leaving with fresh perspectives, strong connections & motivation ✈️ Thanks to #HorizonEU & #MSCA DN! #TopGut #PhD

The new research institute Si-M (Der Simulierte Mensch/The Simulated Human), a joint Charité-TU Berlin venture, officially opened!   We are excited to be a part of this new space, combinining biology, data science and engineering to model human physiology and accelerate medical translation! 🧬

Excited to share our new study showing that CD4⁺ and CD8⁺ T cells communicate via the AICL–KLRF1 axis to sustain cytokine production in precursor exhausted T cells. This support is disrupted in tumors, potentially promoting CD8⁺ T cell exhaustion. 🔗 link.springer.com/article/10.1...

Two of our lab members, Christina Iwert and Lev Petrov, have recently successfully defended their PhD theses! Congrats and wishing you both loads success in your careers! 🎓 @woodenrobo.bsky.social

Halloween in Sawitzki Lab 🎃🧙🕸️

We are at the #EMBLSpatialBiology: Melting Pot in beautiful Heidelberg this week! Exciting poster session today where also Matthias and Adrian shared their work. #ESSB2025

Excited to share our new study on how age-related changes in STAT signaling impact antiviral responses and hyperinflammation in COVID-19! 🧵 Explainer thread by the first author Lev Petrov linked below ⬇️

Rewired type I IFN signaling is linked to age-dependent differences in COVID-19

Petrov et al. identify an age-dependent shift in interferon signaling during SARS-CoV-2 infection, with older individuals favoring a STAT3-driven inflammatory response. This mechanistic insight helps ...

cell.com

📣 We are looking for a master student to join us at the @bihatcharite.bsky.social to work on an exciting project in the field of #cancer and #spatialbiology! 🔬 #singlecell #multiomics

Adrian and Birgit are in Porto this week for a meeting of the TOP-GUT #MSCA Doctoral Network. Lots of fun sharing recent discoveries, planning collaborations and getting hands-on training on organoid culture. 🙌

Waking up our sleeping beauty! Super excited to have Xenium and PhenoCycler now running in the same room 🤩 #SpatialOmics #SpatialBiology #SpatialProteomics #SpatialTranscriptomics #Immunology

📣 Job alert! 📣 We are are looking for a talented bioinformatician to join us at the Berlin Institute of Health at Charité to analyze multiomics data in post-COVID-19 and ME/CSF syndrome research. Please share and come join us! ⬇️ #ImmunoSky #Bioinformatics #Immunology #ComputationalBiology #MedSky

Computational Scientist (d/f/m) in Translational Immunology

Vollzeit | 16.04.2025 | BIH Berlin Mitte

bihealth.org

We’re excited to be a part of the Swarm Learning Initiative, working to accelerate immune response analyses in infectious diseases! Anika, Lev, and Birgit joined the 1st Swarm Learning Symposium at @dzne.science, where Anika shared innovative concepts for ex vivo functional analyses. 📈

Exciting to see this story out — showing that children with MIS-C have high levels of TGFβ, which weakens T cells and reactivates EBV. Blocking TGFβ reversed this effect, making this a potential treatment option! Proud to have contributed our part!

TGFβ links EBV to multisystem inflammatory syndrome in children - Nature

Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.

nature.com

Visited two events with a focus that was new to me - on tech- and methodology. Helpful, technical input and discussions that are often lacking in broader events! ⛰️📊 German Mass Cytometry User Forum - Jena, Germany 1️⃣0️⃣❎️ Single Cell & Spatial Discovery Symposium by 10X Genomics - Munich, Germany

Happy Valentine's Day! 🫶 #FluorescentFriday #SpatialProteomics #Microscopy

As part of BIH Diversity Month, Katherine Deane visited the BIH@Charité and stopped by our lab. Katherine is a renowned expert on accessibility and inclusivity, and we had great time discussing ways to make our lab and the broader scientific community more inclusive!

Lucas @lucasarendholz.bsky.social is presenting his project on post-COVID syndrome (long COVID) at the 8th German Mass Cytometry User Forum in Jena, Germany! 🙌

We're thrilled that the CURE-ME project received funding from the German Federal Ministry of Education and Research! Together with experts from Charité and @tumuenchen.bsky.social, we are investigating the role of Epstein-Barr virus (EBV) in triggering autoreactivity and post-infectious #MECFS.

EBV may trigger autoreactivity and cause ME/CFS – BIH-led CURE-ME research project awarded federal funding - News - BIH at Charité

The consortium project CURE-ME (Characterizing AUtoimmuneREsponses and Defining Targets in ME/CFS) between the Berlin Institute of Health at Charité (BIH), Charité –Universitätsmedizin Berlin and the ...

bihealth.org

Protesting budget cuts for research and education in Berlin! #SaveBrainCity

Congratulations to Julia Stein for earning her Dr.rer.nat. degree from the @freieuniversitaet.bsky.social with a stellar PhD defence last week! Well done, Dr. Stein! 🎓 #Immunosky #PhD #SciSky

Very exciting week for Sawitzki Lab! 🎉 We moved into brand-new lab spaces at the Rahel Hirsch Center for Translational Medicine (BIH & Charité). Plus, we made the leap to Bluesky! 🚀