Sheila Roitman

@sheilaroitman.bsky.social

Moving from Sci-Fi to Science 🔬📚🪴🤿🏕️🇦🇷 🇮🇱 Post-doc at WeigelWorld 🇩🇪, Plants & microbes Past: PhD at Beja Lab, Marine microbiology

📣 A new preprint by noashima.bsky.social! 📣 How does ocean warming affect viral infection? Infection of algae by a giant virus is arrested intracellularly under elevated temperature, with the late replication stage blocked. Infection can later resume, revealing a reversible arrest state 🌊

Reversible inhibition of viral life cycle in response to elevated temperature in a bloom-forming alga

Ocean warming is expected to reshape microbial interactions and community composition, with profound consequences for marine biogeochemical cycles. Host virus dynamics are central to these processes, ...

biorxiv.org

A new paper from the lab on virus-like particles called eCISs www.nature.com/articles/s41... How bacteria evolved thousands of precision nanoinjectors? Some bacteria don’t secrete toxins — they inject them using phage-derived machines called extracellular contractile injection systems (eCISs).

A comprehensive catalogue of receptor-binding domains in extracellular contractile injection systems - Nature Communications

Extracellular contractile injection systems (eCISs) are bacteriophage tail-derived toxin delivery complexes that are present in many prokaryotes. Here, the authors present an analysis of eCIS tail fib...

nature.com

This is such a cool paper as it experimentally addresses the role of the auxiliary metabolic gene nblA in cyanophages showing a large benefit of NblA to the cyanophage and a negative effect on the host photosynthetic apparatus and host photosynthesis www.nature.com/articles/s41...

Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis - Nature

Viral NblA accelerates the cyanophage infection cycle, directs degradation of the host phycobilisome and other proteins, and reduces host photosynthetic light-harvesting efficiency.

nature.com

1/5 🚨🚨 preprint alert! 🚨🚨 I wish to introduce CARDIB, not the singer, but the protein. CARDIB=CARD Inhibitory Binding protein. In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals. www.biorxiv.org/content/10.1...

An ancient anthozoan protein reveals an alternative evolutionary path of antiviral signaling

How antiviral immunity first arose in animals is a central question in evolutionary biology. Using the sea anemone Nematostella vectensis, we identify CARDIB, a previously uncharacterized gene located...

biorxiv.org