Excited to share our new preprint! biorxiv.org/content/10.6... We know that mitochondria make contacts with organelles, but determining whether these contacts establish functionally distinct mitochondrial populations has been challenging.

A Modular Platform for Purification of Organelle-associated Mitochondria Reveals Functional Specialization at Organelle Contact Sites

Mitochondria perform diverse metabolic and signaling functions, yet how these activities are spatially organized within the mitochondrial network of cells remains poorly understood. Organelle contact ...

biorxiv.org

Job alert! I'm recruiting a new post-doc to work on mechanisms of co-translational quality control in the ER. Looking for expertise in ribosome biology and yeast genetics/cell biology. Please reach out to me with any questions. www.dundee.ac.uk/work-for-us/...

Postdoctoral Research Assistant - UOD2336

Closing date: Thursday 27 August 2026, 23:59

dundee.ac.uk

New preprint from the lab, led by the ever-talented grad student Tessa Lochetto @tlochetto.bsky.social! We find that loss of our favorite phosphatase Pptc7 decreases lean mass, induces skeletal muscle dysfunction, and causes metabolic derangements in adult mice: doi.org/10.64898/202... /1

Sustained loss of Pptc7 triggers variable skeletal muscle dysfunction and diminished body mass through dysregulation of BNIP3

The mitochondrial phosphatase PPTC7 is required to sustain mammalian metabolism, as its global knockout (KO) triggers hypoketotic hypoglycemia and perinatal lethality in mice. However, the extent to w...

doi.org

DOJ Launches Criminal Investigation Into All Women — theonion.com/doj-launches...

DOJ Launches Criminal Investigation Into All Women

theonion.com

New fact check of Director Bhattacharya, this time regarding multi-year funding... 27unihted.substack.com/p/fact-check... 1/2

Fact Check, Part 2: NIH Director Conceals the Harmful Consequences of Multiyear Funding Transition

NIH Director Jay Bhattacharya oversells benefits, ignores harms from the rapid transition to multiyear funding during the March 17, 2026 House Appropriations Committee Hearing

27unihted.substack.com

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1 rupress.org/jcb/article-...

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Hurwitz et al. leverage a novel FRET-based approach to quantify conformational dynamics of Mfn1, a member of the dynamin superfamily that mediates mitochon

rupress.org

It’s out! Huge thanks to our reviewers and the editors at JCB! This collaboration was so fun and Sophie Hurwitz was a science rock star 🌟This story is about the mitofusin paralogs (Mfn1 and Mfn2) - large GTPases in the dynamin superfamily. Their primary role is to mediate outer membrane fusion.

Hurwitz, @shoppins.bsky.social and colleagues leverage a powerful FRET system to uncover novel insights into the energetic landscape and conformational dynamics of mitofusin, the mitochondrial outer membrane fusion machine. rupress.org/jcb/article/... #Mitochondria

I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join for talks from @zakbaker.bsky.social (from @pagliarini-lab.bsky.social) and Sara Wong (from Adam Hughes' lab) on the intersection of mitochondria and lipid metabolism! Register here: www.asbmb.org/meetings-eve...

Lipid Research Division Seminar Series

April 9, 2026 | 12 p.m. Eastern

asbmb.org

Our @statnews.com survey of NIH-funded researchers drew nearly 1,000 responses from 45 states (plus DC and Puerto Rico). Here's a short thread on 5 scientists' whose labs and lives have been deeply impacted by federal policies 🧵

A grad student in my lab wrote this article sharing her growth in grad school. Amy is fantastic and I am lucky to work with her. www.asbmb.org/asbmb-today/...

The tortoise wins: How slowing down saved my Ph.D.

Graduate student Amy Bounds reflects on how slowing down in the lab not only improved her relationship with work but also made her a more productive scientist.

asbmb.org

Giving the gift of negative data 🥰 Since I joined @lsajournal.org I have handled several stellar manuscripts that report null results. These papers do very well and reviewers almost always appreciate them! Thanks @rockefeller.edu news team for the article! www.rockefeller.edu/news/38829-t...

The value of publishing negative data - News

Scientific journals love news-worthy results. Editors want to publish studies with novel data that scientists will eagerly read and cite in their own work. Because of this desire for novelty, studies ...

rockefeller.edu

Had a great time at #ascb2025! I learned a lot and connected with fantastic scientists. I appreciate the thoughtful member organizers for great sessions and trainees for sharing your science. Finally, thanks for your service @marymunson4.bsky.social - you’re the best.

@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"

Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...

Structural insights into GTP-coupled conformational changes in Mfn1 revealed by time-resolved transition metal ion FRET.

Outer mitochondrial membrane fusion is mediated by the mitofusin paralogs Mfn1 and Mfn2. Nucleotide-driven self-assembly and conformational changes are required for regulated membrane fusion activity,...

urldefense.com