Congratulations to Cole Jensen, MPH, a PhD Student in Computational Biology & Bioinformatics and a member of the @skleinstein.bsky.social Lab at @yalemedicine.bsky.social, on being chosen for a prestigious National Institutes of Health (NIH) F31 Award bit.ly/4bWbFtB
Steven Kleinstein
@skleinstein.bsky.social
Computational immunologist; Professor at Yale School of Medicine; Co-Director, Computational Biology & Biomedical Informatics; B cell receptor sequencing analysis, http://immcantation.org + multi-omics signatures of infection, vaccination & autoimmunity.
🚀 Registration is now OPEN for AIRR Community Meeting VIII: Decoding and Recoding Immunity! Join us June 8–11, 2026 at Yale University (USA) or attend virtually. 💸 Early-bird rates available until April 15! 🔗 Register: tinyurl.com/airrcmeeting8 #AIRRC8 #immunosky
AIRR Community Meeting VIII.
tinyurl.com
Immcantation.org user or interested in #Bcell & #Tcell repertoire analysis? #AIRRseq 🚨Register now for the "2026 Immcantation Users Group Meeting" 🗓️FREE virtual meeting on January 22, 2026 from 10AM – 1:30PM ET. 🔗Program & registration: immcantation.github.io/users-meetin...
Immcantation.org user or interested in #Bcell & #Tcell repertoire analysis? #AIRRseq 🚨Register now for the "2026 Immcantation Users Group Meeting" 🗓️FREE virtual meeting on January 22, 2026 from 10AM – 1:30PM ET. 🔗Program & registration: immcantation.github.io/users-meetin...
Interested in pursuing a PhD in Computational Biology and Biomedical Informatics (CBB) at Yale? Join us for a CBB PhD Virtual Open House Tuesday, November 11 | 8:00–9:00 PM ET 👉 Register here: yalesurvey.ca1.qualtrics.com/jfe/form/SV_... @yalecbb.bsky.social
excited to announce that this January we are relocating to Yale to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI): @yalecsei.bsky.social looking to hire 2 postdocs to join us in this endeavor. more details can be found here: sites.google.com/uw.edu/statp...
SPE - join us
Postdoctoral position: In January 2026, we are relocating to Yale university to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI). We are looking for talented postd...
sites.google.com
Interested in pursuing a PhD in Computational Biology and Biomedical Informatics (CBB) at Yale? Join us for the CBB PhD Virtual Open House Tuesday, October 21 | 8:00–9:00 PM ET 👉 Register here: yalesurvey.ca1.qualtrics.com/jfe/form/SV_... @yalecbb.bsky.social
TODAY is the deadline for abstract submission for the 2026 Immcantation Users Group Meeting! immcantation.github.io/users-meetin...
2026 Immcantation Users Group Meeting
immcantation.github.io
🚨 Immcantation.org user or interested in #Bcell repertoire analysis? 🗓️ Join the FREE virtual 2026 Immcantation Users Group Meeting 📅 Jan 22, 2026 | ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2025 🔗 immcantation.github.io/users-meeting/2026 #AIRRseq #Immcantation
🚨 Immcantation.org user or interested in #Bcell repertoire analysis? 🗓️ Join the FREE virtual 2026 Immcantation Users Group Meeting 📅 Jan 22, 2026 | ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2025 🔗 immcantation.github.io/users-meeting/2026 #AIRRseq #Immcantation
🚨 One week left! 🚨 Don’t forget to submit your 250-word abstract by October 1st! Share how you use Immcantation and contribute to building a supportive, collaborative research community. 🔗 2026 Immcantation Users Group Meeting immcantation.github.io/users-meeting/2026 #airrseq #immunosky
🚨 Immcantation.org user or interested in #Bcell repertoire analysis? 🗓️ Join the FREE virtual 2026 Immcantation Users Group Meeting 📅 Jan 22, 2026 | ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2025 🔗 immcantation.github.io/users-meeting/2026 #AIRRseq #Immcantation
Our condolences to family and friends of our long collaborator Atul Butte. Word of his death came from Euan Ashley of @stanfordmedicine.bsky.social #memorial www.linkedin.com/posts/euanas...
Atul Butte died yesterday. | Euan Ashley
Atul Butte died yesterday. The world lost a giant. A big bear of a man. With a huge smile. With love for everyone. With energy that could power a room. I loved everything about Atul. I loved how he wa...
linkedin.com
Our collaborators @camilahcoelho.bsky.social @vivianasimonlab.bsky.social (+ others) show that monovalent XBB.1.5 vaccines recall mostly cross-reactive antibodies to ancestral SARS-CoV-2, not robust de novo responses. @lancetmicrobe.bsky.social #ImmuneSky www.thelancet.com/journals/lan...
Mapping of human monoclonal antibody responses to XBB.1.5 COVID-19 monovalent vaccines: a B cell analysis
Our findings offer key molecular insights into whether strain-specific boosters elicit sufficient protection against SARS-CoV-2 emerging variants. This knowledge can inform decisions on booster design...
thelancet.com
Next week, we are hosting an international scientific workshop focused on the pathogenesis of #LongCovid at @yalemed.bsky.social. Please join us on May 15th to learn about what we know and what we need to investigate next to get to the root causes to accelerate therapies 👇🏼👇🏼
Don’t forget! 🌺🧪 Our HIPC symposium is happening tomorrow — join us for a great lineup of talks from @bjoernpeters.bsky.social, @lungdrc.bsky.social, @settelab.bsky.social, Victoria Zyulina & Thomas Hagan Tues May 6th | 8:30-10:30 am | Room 313C #Immunology #AAI2025 #HIPC
Come get our #immune data, free #FAIRsharing is at @immportdb.bsky.social - from @columbiauniversity.bsky.social @icahn.bsky.social @yalemedicine.bsky.social @stanfordimmunology.bsky.social @benaroyaresearch.bsky.social @lji.org MIT, Seattle Children's #AAI2025 #ImmuneSky #IDsky
What if LLMs could “read” & “write” biology? 🤔 Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝 🔗 Blog: research.google/blog/teachin... 🔗 Preprint: biorxiv.org/content/10.1...
Teaching machines the language of biology: Scaling large language models for next-generation single-cell analysis
research.google
Below, from earlier today, confirmed @statnews.com www.statnews.com/2025/04/18/n...
NIH said to have halted awarding of new grants to more top universities
Universities whose NIH funding has been frozen may face further strain as the agency holds off awarding new grants to at least a half dozen of them, according to an internal email.
statnews.com
Per source, NIH has been instructed to hold off from issuing ALL awards to Harvard, Cornell, Columbia, Brown, and Northwestern (including med schools) Agency staff have also been instructed to not speak about this funding freeze to grantees and applicants
Exciting news!! We are happy to announce that we will have a HIPC Symposium at @aai.org on Tues, May 6th. HIPC will also have a Super Booth at #AAI2025 along with @iedb.bsky.social and the iAKC Project. Check out the full Symposia list, and see you there! 🔗: immunology2025.aai.org/guest-sympos...
Guest Symposia - IMMUNOLOGY2025™
Information and details about Guest Symposia to be presented at IMMUNOLOGY2025™!
immunology2025.aai.org
Great to have our latest review "The cellular factors that impair the germinal center in advanced age" out @jimmunol.bsky.social. Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2. doi.org/10.1093/jimm...
WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025
🚨☀️ Hey Bluesky! Know anyone near the following cities that would be willing to help us Stand Up for Science? ☀️🚨 Annapolis, MD Bismarck, ND Boise, ID Charleston, WV Dover, DE Jackson, MS Anchorage or Juneau, AK Montpelier, VT Richmond, VA Send them our way! #standupforscience2025
Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests
New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies
scim.ag
Presentations from the 2025 Immcantation Users Group Meeting are now available on the Immcantation YouTube channel! Thank you to our speakers and participants! www.youtube.com/playlist?lis... #immcantation #airrseq #immunosky
2025 Immcantation Users Group Meeting - YouTube
The 2025 Immcantation Users Group Meeting (https://immcantation.github.io/users-meeting/2025/index.html) took place on January 30th, 2025. It served as a vir...
youtube.com
Our collaborators identify multi-omic factor that predicts #LongCovid Among 50+ authors include @sesmalab.bsky.social @joanndarce.bsky.social @bjoernpeters.bsky.social @slimfourati.bsky.social @droferlevy.bsky.social @leying2024.bsky.social #IDsky #MedSky www.biorxiv.org/content/10.1...
Identification of a multi-omics factor predictive of long COVID in the IMPACC study
Following SARS-CoV-2 infection, ∼10-35% of COVID-19 patients experience long COVID (LC), in which often debilitating symptoms persist for at least three months. Elucidating the biologic underpinnings ...
biorxiv.org
Our collaborators @rgottardo.bsky.social and Ken Stuart (+ others) describe tagtango, an application to compare #single-cell annotations. #bioinformatics academic.oup.com/bioinformati...
tagtango: an application to compare single-cell annotations
AbstractSummary. In this article, we present tagtango, an innovative R package and web application designed for robust and intuitive comparison of single-c
academic.oup.com
Unlocking new insights with nipalsMCIA. This tool speeds up data analysis for big datasets by clustering and visualizing info faster than before. Check it out for both bulk and single cell data on Bioconductor with how-to guides and extras online.
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares.
Published in Bioinformatics (Oxford, England)
doi.org
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares https://www.biorxiv.org/content/10.1101/2024.06.07.597819v1
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares https://www.biorxiv.org/content/10.1101/2024.06.07.597819v1
Motivation: With the increased reliance on multi-omics data for bulk and single cell analyses, the a
biorxiv.org
Interested in B cell receptor repertoire analysis? We have a great set of speakers lined up for the “2025 Immcantation Users Group Meeting!” Check out the UPDATED program and register for this free virtual meeting taking place on 1/30/25 10AM-1:40PM (ET) at: immcantation.github.io/users-meetin...