Neurodevelopment is such a fun field because so much is new to explore and define. But also that means it can be unclear. In our new review out this week @cp-trendsneuro.bsky.social, we try to synthesize the confusing field of neural intermediate progenitors authors.elsevier.com/a/1msKvbotqB...

New work from our team, led by the incredible @emily-hill.bsky.social out today @cp-neuron.bsky.social. Including some exciting additions from our prepint. Thread below! authors.elsevier.com/a/1ms0u3BtfH...

Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...

I've been really hoping to see more manuscript threads here on 🦋, so here comes one!!! This is brand new work from the lab that took us in very unexpected directions and to exciting findings led by the amazing @emily-hill.bsky.social. Preprint here www.biorxiv.org/content/10.1... and 🧵below:

Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.

Immunity@cp-immunity.bsky.social · last yr.

Online now: Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease

Trying my best to focus on some positive science content. We feel so grateful to have our work highlighted on the cover of @naturecellbiology.bsky.social! This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz

This is our future! A PhD on its own is a roller coaster with little stability. These extra hurdles for some of our brightest scientists need to be eliminated--not exacerbated.

Christina Ramelow@christinaramelow.bsky.social · last yr.

Fresh off the press by @thetransmitter.bsky.social on the uncertainties trainees are facing with diversity-based funding. I’m thrilled to share a piece of my story & continue to be a champion for diversity. Ty to the journalists & trainees for their work! www.thetransmitter.org/funding/a-gu...

New preprint! A really fun project spearheaded by amazing graduate student @christinaramelow.bsky.social and a collaboration with Srikant Rangaraju's group. www.biorxiv.org/content/10.1...

Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling

Deep molecular phenotyping of cells at transcriptomic and proteomic levels is an essential first step to understanding cellular contributions to development, aging, injury, and disease. Since proteome...

biorxiv.org

A great opportunity to join this special team! Details below

Emory Brain Organoid Hub@brainorganoidhub.bsky.social · 2y ago

We're excited to announce that the Brain Organoid Hub is hiring! If you, or someone you know, has an interest in working with stem cells and brain organoids as a Research Specialist, please feel free to apply 🔬 www.linkedin.com/jobs/view/41...

Hi #neuroscience community! This is one of my favorite posts ever. In close collaboration with @liddelowsa.bsky.social and Ye Zhang, we've built a new tool that we are eager to share! www.webseq.net

WEBseq

share freely

webseq.net

First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵

Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma

Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...

rdcu.be