🧠‼️ Socioeconomic variables show the strongest associations with the brain out of 649 measures—surpassing cognition and mental health. Grateful for the chance to write a perspective with @ted-satterthwaite.bsky.social about @smarek0502.bsky.social and team's important findings! tinyurl.com/bdhk6bc8

Childhood environments shape the brain

Socioeconomic factors top the list of influences on children’s brain structure and function

science.org

Scott Marek@smarek0502.bsky.social · 2mo ago

What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...

Thanks @ariellekeller.bsky.social ! And yes, please check out the amazing perspective by @lucindasisk.bsky.social and @ted-satterthwaite.bsky.social!

Arielle Keller@ariellekeller.bsky.social · 2mo ago

The evidence is clear: socioeconomic conditions play an *enormous* role in brain development Amazing work by @smarek0502.bsky.social &co doi.org/10.1126/science.aee6213 +perspective by @lucindasisk.bsky.social & @ted-satterthwaite.bsky.social doi.org/10.1126/science.aei3393 #neuroskyence #PsychSky

This is one of the most socially important scientific findings I've ever been a part of. SES has a larger cross-sectional effect on brain function than any other variable. Prediction of IQ from brain data is actually mostly just predicting SES. Mind blowing.

Scott Marek@smarek0502.bsky.social · 2mo ago

What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...

What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

The 6x US memory champion – Nelson Dellis – can memorize a deck of cards in 40 seconds and knows the first 10K digits of pi. To figure out how, he let us peak inside his brain. Here is what we learned in our precision brain mapping study www.biorxiv.org/content/10.6... youtube.com/shorts/MryMq...

how does his brain do it ? #neuroscience #memory #sport Nelson Dellis 6x US memory champion

YouTube video by Roselyne Chauvin

youtube.com

Inter-individual variability of neurotransmitter receptor and transporter density in the human brain | doi.org/10.1007/s004... How do neuroreceptor distributions vary across people?

🚨 New preprint: Objective Quality Assessment for Precision fMRI Precision functional mapping (PFM) enables individual-level brain network studies — but demands more, and better, data. We introduce an objective framework to determine when a dataset truly supports interpretable, replicable PFM.

Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory. n.pr/4kpKWtv

This complex brain network may explain many of Parkinson's stranger symptoms

Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.

n.pr

I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment. www.nature.com/articles/s41...

Check out our new work on the relationship between glioma and system-level functional networks! We identify that nearly all gliomas localize within a common brain functional network, Action-Mode Network (AMN) . biorxiv.org/content/10.64898/2026.01.05.697608v1

This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brain’s attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications! doi.org/10.1038/s414...

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

Alert!!!! “An Action Networks Model for Pain” We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it. 👉 thread below 🧵 osf.io/preprints/ps...

My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!

It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy

Love to see this conversation starting! "Study design features increase replicability in brain-wide association studies" Full article led by Kaidi Kang and Simon Vandekar + awesome News+Views by @roselynechauvin.bsky.social & @ndosenbach.bsky.social! 👇 www.nature.com/articles/s41... #neuroskyence

Study design features increase replicability in brain-wide association studies - Nature

Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association ...

nature.com

Roselyne Chauvin@roselynechauvin.bsky.social · 2y ago

Great conversations with @ndosenbach.bsky.social while preparing this Nature News & Views on the new Kang et al. Ready to have the same with everyone here. Thoughts? What other practice should be investigated to help BWAS reproducibility? www.nature.com/articles/d41...