Double PI act @sorengrubb.bsky.social @amreenmughal.bsky.social continuing in brains with #cilia & #centrosome diversity across microvascular system, with striking species differences on cilia metrics & directionality of spaces sampled. Deep read: www.biorxiv.org/content/10.1... #UKCilia 5/8

Want to know about our latest research on #primarycilia and #centrosomes in #brain #microvasculature? Join this e-symposium tomorrow! 🧪

Mill_lab@cilialab.bsky.social · 7mo ago

We must have been #ExtraNice this year- our #cilia & #centrosome 🧪 community- 🎅 Santa just dropped the 1st session of 2026 line-up @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposia- www.eventbrite.co.uk/e/bscb-genso... See you on the other side! Happy Holidays!

Thanks for a great 2025!🎆🥳🎉 We’re proud to share highlights from this year at Neuroscience Academy Denmark (NAD) – showcasing the incredible work of our PhD students. 👩‍🎓👨‍🎓 A big thank you to @lundbeckfonden.bsky.social for supporting our mission. 🙏 #Neuroscience #PhD #Research #Collaboration 🧪

New on bioRxiv! 🚨 “Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature” This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia! 🔗 www.biorxiv.org/content/10.1... 🧪 🧵1/8

🎥 NAD 2025 Annual Meeting Highlights From Oct 3–5, Neuroscience Academy Denmark hosted: ✅ 400+ participants ✅ 100 posters ✅ Keynotes on precision psychiatry, brain barriers, ultrasound treatments, brain stimulation, sleep & circadian rhythms We look forward to next year! #Neuroscience #NAD2025 🧪

“Well I don’t like that study because it doesn't give me the result I want’

We are excited to report: Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice Vittani et al. PNAS (2025) pnas.org/doi/10.1073/...

The first Master’s student with me as main supervisor graduated today! I’m proud 🥹

🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧪🧵

Playing around with my 3yo daughter and an antique microscope. Looked at some #dandelion petals and a stamen using a Carl Zeiss P.A. 35 microscope using reflected light. 🧪

@pkpd-babe.bsky.social Can I be added to the science post? My orcID: orcid.org/0000-0002-67...

Amazing work out by Hirase Lab 🤩

Hajime Hirase@hajimehirase.bsky.social · last yr.

Vittani, Lee, Wang, Hiraoka, et al. KI mouse expressing red fluorescent blood In situ SpyTag/Catcher attachment of biosensor ECS SpyCatcher to capture BBB leak doi.org/10.1101/2025... We hope this method is useful to a wide range of the biology community.

Join our #PhDcourse on #openscience datasets and tools in #Neurophysiology! We'll dive into #EM, #inVivo #physiology, behavioural analysis tools, and a talk on creating animations from open data! @quorumetrix.bsky.social 📢 Free for NorDoc PhD students, but open to all! Apply now! lnkd.in/dU_fxqqu

Pass it on. #StandWithUkraine

Publications in the past week built substantially on our knowledge of the brain's waste disposal system—glymphatics—and the implications on sleep and brain aging. Featuring exceptional work by Nedergaard Lab and @jonykipnis.bsky.social erictopol.substack.com/p/our-sleep-... open-access

Our Sleep, Brain Aging, and Waste Clearance

How sleep prevents "dirty" brains that age faster

erictopol.substack.com

🤘🏻The study I have been waiting for 30 years! Only Scandinavians can pull this out let alone publish it in a Scandinavian pain journal 🤘🏻 #painscience #physio #painresearch #ignobel2025 www.degruyter.com/document/doi...

SERVICE UPDATE We normally don't ask you to "share like and subscribe" but please distribute this. You are now able to delete the link after it embeds on your post so you can get those precious extra characters, and we will catch your post mentioning research. #AcademicSky #Medsky #HigherEd

Always fascinating these links between heart and brain ilnesses academic.oup.com/brain/advanc... #HeartBrainAxis

Loss of glymphatic homeostasis in heart failure

Heart failure can lead to reduced cerebral blood flow, neurodegeneration, and cognitive decline. In a mouse model of heart failure, Kritsilis et al. show t

academic.oup.com

lymphatics

🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. Read more: e11.bio/news/roadmap

You can generate a #podcast with two hosts discussing a research paper using notebooklm.google.com I have tried it with a couple of papers (including my own 😂), it is a nice way of getting a summary. Try it out!

🧠NON-NEUROCENTRIC STARTER PACKS FOR BRAIN RESEARCH: I this thread 🧵 I will post starter packs for fields of research not directly related to neurons: #meninges, #vasculature, #glia, #immunecells, #dementia, #headache, #microscopy, and resources to get started with #Bluesky.

Here we show how 🧠 #precapillarysphincters react to #CorticalSpreadingDepolarization which is associated with #migraine with #aura 🤕. #CSD has 3 phases: constriction, dilation, and a long lasting constriction that interrupts #bloodflow🩸 to #capillaries (Tinyurl.com/euasfses).

#Neurovasculature changes from the #arterial to the #venular end. Here I have tried to draw the #cell morphologies realistically. #Endothelialcells go from spindle shaped to rhombic shaped and #muralcells from #smoothmuscle to #pericytes. #Astrocytes same shape. www.sciencedirect.com/science/arti...

Here is a #precapillarysphincter. As #arterioles 🟢 dive into the 🧠, they branch to smaller vessels. When larger arterioles (15-25um) branch into #capillaries, they need a #sphincter (3-4um) to reduce #RBC flow⚫️ and pressure in the #capillary. The resistance is provided by #muralcell🔴 encirclement.

Here we show how #microglia contact #pericytes and #endothelialcells in the #venule end of the #capillary bed. Note also how a #primarycilium of an #interneuron invaginates the microglia. But why? 🤔 journals.sagepub.com/doi/full/10.... @gazz4science.bsky.social

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky 1. The importance of stupidity in scientific research Open Access journals.biologists.com/jcs/article/...

Tell me, If you want to join the Migraine @ Headache starter pack. #Migraine #Headache #neuroscience #Neurology #pain go.bsky.app/U8U8wfW

You wanted starter packs to be searchable. Our engineers are busy keeping us online, so in the meantime, an independent developer built a new searchable library of starter packs. This is the beauty of building in the open 🦋

Bluesky Starter Pack@blueskystarterpack.com · 2y ago

blueskystarterpack.com

Here is a starter pack on the #Meninges, #CSF, and #Glymphatics. Please share and let me know if you should be on the list and I will add you! go.bsky.app/NLcabwc