Nicholas Tatonetti, PhD

@tatonetti.bsky.social

Making drugs safer one billion data points at a time. @CedarsSinai Prof, @Stanford BMI, @Columbia DBMI, EiC of BioData Mining, he/they enby 🏳️‍🌈

the most realistic scene in Jurassic Park is when two scientists make a questionable decision — traveling to an undisclosed location with a strange man — on the promise of three years of modest funding

It's time again for the AMIA Translational Bioinformatics Year-in-Review! This year: 2k papers triaged, 600+ reviewed. The final set is wild. Foundation models, multimodal bio, spatial everything, generative proteins, and some pure brain candy. Can't wait to present! #Amplify2026

OnSIDES v3.1.1 is out! 🎉 Updated with drug labels through April 2026 from all four sources (US, UK, EU, Japan): - 41K+ product labels - 6.9M drug–adverse event pairs - 4,097 ingredients Also fixes some bugs — if you're using that., please upgrade. github.com/tatonetti-la...

Release OnSIDES v3.1.1 · tatonetti-lab/onsides

Updated April 2026 with the latest drug labels from all four regulatory sources. Summary Type v3.1.0 v3.1.1 Products 42,268 41,119 Adverse effects 5,472,613* 6,928,666 Ingredients 1,955 ...

github.com

GI fellow Jamil Samaan noticed something odd when using AI ambient scribes and speech transcription tools Clinicians with non-native English accents appeared to confuse the model He and Yassi Fatapour decided to investigate, now out in npj Digital Medicine www.nature.com/articles/s41...

Accent related errors in clinical speech transcription and a LLM-based remedy - npj Digital Medicine

npj Digital Medicine - Accent related errors in clinical speech transcription and a LLM-based remedy

nature.com

I suspect Holly Mitchell is going to find in the coming years that she shares Henry Waxman's legacy as someone who blocked a whole part of the LA region from getting rail for decades due to needless, pointless capitulation to fearmongering. Her time on the Metro Board will not be remembered kindly.

Is "Agent Engineering" the next big thing? Getting so-called "AI Agents" to work together effectively isn't trivial. @moorejh.bsky.social and I discuss the need for rigorous development in our latest editorial in BioData Mining biodatamining.biomedcentral.com/articles/10....

From prompt engineering to agent engineering: expanding the AI toolbox with autonomous agentic AI collaborators for biomedical discovery - BioData Mining

biodatamining.biomedcentral.com

The top three science funders are the US, China, and Japan. The three fund more science than every other country, combined. In 2024, the US funded more scientific research than China and Japan, combined. The US also funds more science than every other country except for Japan and China, combined.

David Shiffman, Ph.D. 🦈@whysharksmatter.bsky.social · 12mo ago

For the eleventy billionth time: Attacks on science funding and science jobs in the United States don’t mean that science will just move elsewhere. It means a lot less science for everyone. There aren’t enough jobs or funding everywhere else )combined) for US scientists to just move.

With the correct rhetorical device you can make complete jibberish sound like poetry. Just ask Shakespeare (or better read Forsyth's The Elements of Eloquence)

Politico@politico.com · last yr.

A new immigrant detention center will be opening in Indiana called the “Speedway Slammer,” modeled after Florida’s “Alligator Alcatraz.” On #playbookpod, Megan Messerly explains why the rhetoric used by the administration to describe these centers is significant. 🎧 Listen here: ow.ly/yY5B50WAzH8

Just came across this fail. Literally everything that's wrong with AI/tech in healthcare. Not only is the patient and doctor buried in their devices, but they're facing AWAY from each other 🤦‍♂️!! Technology should facilitate and center the humanity of healthcare. Not do whatever this is.

From left to right. Patient facing left and looking at their phone. Doctor facing right looking at a tablet.

Excited that our paper on GenAI-based text normalization is out at Journal of Biomedical Informatics! If you ever had a bunch of messy text and need to map it to a controlled terminology, then this is the method for you. www.sciencedirect.com/science/arti... Special 👏 to Jacob Berkowitz!!

Biomedical text normalization through generative modeling

A large proportion of electronic health record (EHR) data consists of unstructured medical language text. The formatting of this text is often flexibl…

sciencedirect.com