A review of 18 studies found no consistently reproducible subtypes of schizophrenia, suggesting that differences in brain structure across patients may reflect a spectrum rather than discrete biological categories.
Neuroimaging-Based Subgroups in Schizophrenia: A Critical Appraisal of Clustering Studies
Efforts to define biologically grounded subtypes of schizophrenia have increasingly leveraged neuroimaging data and clustering algorithms. Such approaches aim to capture patient-level heterogeneity…
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